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ADAMTSL4 and SORBS3
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
ADAMTSL4
SORBS3
Gene Name
ADAMTS-like 4
sorbin and SH3 domain containing 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cellular_component
Interstitial Matrix
Endoplasmic Reticulum Lumen
Nucleus
Cytosol
Cytoskeleton
Focal Adhesion
Molecular Function
Protease Binding
Metalloendopeptidase Activity
Protein Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Transcription Factor Binding
Vinculin Binding
Biological Process
Protein O-linked Glycosylation
Proteolysis
Apoptotic Process
Extracellular Matrix Organization
Protein O-linked Fucosylation
Positive Regulation Of Apoptotic Process
Post-translational Protein Modification
Cellular Protein Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Muscle Contraction
Actin Filament Organization
Cell Adhesion
Cell-substrate Adhesion
Positive Regulation Of MAPK Cascade
Positive Regulation Of Cytoskeleton Organization
Positive Regulation Of Stress Fiber Assembly
Pathways
Post-translational protein modification
O-glycosylation of TSR domain-containing proteins
O-linked glycosylation
Smooth Muscle Contraction
Drugs
Diseases
GWAS
Rhegmatogenous retinal detachment (
23585552
)
HIV-1 control (
20205591
)
Protein-Protein Interactions
106 interactors:
ADAMTSL5
AMMECR1
APOL6
AQP1
ARNT2
ASPSCR1
C19orf66
C6orf165
CATSPER1
CCDC26
CHCHD2
CLEC18A
COL8A1
CPNE7
CREB5
CST2
CTSB
CXCL16
CYP2S1
DGCR6
DIP2A
DLK2
DNPEP
DSCR8
EIF4E2
FAH
FAM124B
FARS2
FBLN1
FBXW5
FHL3
FKBP1B
FLNA
FRS3
GATA2
GIP
GLRX3
GMCL1P1
GNE
GNMT
GOLGA8EP
HGF
HOXA1
KIF1A
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-4
LCE1B
LCE2D
LCE3C
LCE3E
LCE4A
LGALS14
LINC00671
LMO1
LMO2
LONRF1
LRRC29
MAPKBP1
MID2
MORN3
MVP
NATD1
NMUR2
NTF4
NTN4
OLFM3
PID1
PIN1
PLSCR1
PRKAB2
PTGER3
RAB2B
RCHY1
RHOJ
SALL2
SLC23A1
SLC6A20
SMARCC1
SORBS3
SPATA8
SPINK2
SPRY2
STK16
SUSD6
TAPBPL
TCEA2
TMEM150A
TMSB4XP6
TOP3B
TRIM42
TRIP6
TSSK3
TUBGCP4
ZNF417
ZNF587
46 interactors:
ABL1
ADAM15
ADAMTSL4
AKT1
ARNT2
CBLB
CPNE2
CPSF7
DDX17
DIP2A
DLG5
DMRTB1
DVL2
EFS
EIF3H
FAM154A
FASLG
FLOT1
HNRNPK
HNRNPUL1
INPPL1
KIAA0408
KIAA1217
MAPK1
MAPK3
NCKIPSD
NOTCH3
PAK1
PAK2
PAK7
RBMX
SAFB2
SH2D4A
SOCS7
SRCIN1
TBC1D22B
TRIM23
TRIM27
TRIM41
VARS2
VPS37B
VPS37C
ZBED1
ZBTB25
ZBTB7B
ZC4H2
Entrez ID
54507
10174
HPRD ID
18237
11535
Ensembl ID
ENSG00000143382
ENSG00000120896
Uniprot IDs
F8WAD0
Q6UY14
Q9UFG7
O60504
PDB IDs
2CT3
2DLM
2NWM
2YUP
Enriched GO Terms of Interacting Partners
?
Multicellular Organismal Development
Keratinization
Organ Development
Developmental Process
Keratinocyte Differentiation
System Development
Anatomical Structure Development
Epidermis Development
Tissue Development
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Epidermal Cell Differentiation
Sensory Organ Development
Response To Organic Substance
Organic Anion Transport
Positive Regulation Of Neuron Projection Regeneration
Regulation Of Transcription From RNA Polymerase II Promoter
Epithelium Development
Cellular Response To Thyroid Hormone Stimulus
MRNA Transcription From RNA Polymerase II Promoter
Skin Development
Positive Regulation Of Transcription, DNA-templated
Transepithelial Transport
Semicircular Canal Development
Positive Regulation Of Gene Expression
Regulation Of Branching Involved In Salivary Gland Morphogenesis
MRNA Transcription
Response To Thyroid Hormone
Negative Regulation Of Hydrolase Activity
Cell Differentiation
Negative Regulation Of Protein Metabolic Process
Cellular Response To Organic Substance
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Gene Expression
Regulation Of Cellular Amino Acid Metabolic Process
Transcription, DNA-templated
Regulation Of Cellular Ketone Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
RNA Biosynthetic Process
Regulation Of Metabolic Process
Fc Receptor Signaling Pathway
Regulation Of Protein Kinase Activity
Regulation Of Kinase Activity
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Protein Metabolic Process
Regulation Of Cellular Process
Negative Regulation Of Protein Kinase Activity
Intracellular Signal Transduction
Negative Regulation Of Kinase Activity
Regulation Of Protein Metabolic Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
RNA Metabolic Process
Regulation Of Protein Tyrosine Kinase Activity
Biosynthetic Process
Regulation Of Gene Expression
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Innate Immune Response
Response To Insulin
Immune Response
Regulation Of Protein Phosphorylation
Negative Regulation Of Transferase Activity
Response To Epidermal Growth Factor
Immune Response-regulating Signaling Pathway
Positive Regulation Of Protein Kinase Activity
Regulation Of Golgi Inheritance
Negative Regulation Of Protein Phosphorylation
Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Kinase Activity
Regulation Of Cellular Protein Metabolic Process
Caveolin-mediated Endocytosis
Cellular Response To Insulin Stimulus
Cell Morphogenesis Involved In Differentiation
Protein Autophosphorylation
Positive Regulation Of Protein Phosphorylation
Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Protein Tyrosine Kinase Activity
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Phosphorus Metabolic Process
Tagcloud
?
abl
baalc
bcr
cd83
ciita
council
ctnnd1
e2993
gab1
gli1
hubs
il15
irs1
p185bcr
p210bcr
pilrb
ptp4a3
rab21
serpinb9
spp1
spry1
supervised
transcriptomic
tspan16
ukall
underexpressed
unsupervised
xbp1
xii
Tagcloud (Difference)
?
abl
baalc
bcr
cd83
ciita
council
ctnnd1
e2993
gab1
gli1
hubs
il15
irs1
p185bcr
p210bcr
pilrb
ptp4a3
rab21
serpinb9
spp1
spry1
supervised
transcriptomic
tspan16
ukall
underexpressed
unsupervised
xbp1
xii
Tagcloud (Intersection)
?