ADAMTSL4 and LCE3E

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ADAMTSL4	LCE3E
Gene Name		ADAMTS-like 4	late cornified envelope 3E
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Interstitial Matrix Endoplasmic Reticulum Lumen
	Molecular Function	Protease Binding Metalloendopeptidase Activity Protein Binding
	Biological Process	Protein O-linked Glycosylation Proteolysis Apoptotic Process Extracellular Matrix Organization Protein O-linked Fucosylation Positive Regulation Of Apoptotic Process Post-translational Protein Modification Cellular Protein Metabolic Process	Keratinization
Pathways		Post-translational protein modification O-glycosylation of TSR domain-containing proteins O-linked glycosylation
Drugs
Diseases
GWAS		Rhegmatogenous retinal detachment ( 23585552)	Common traits (Other) ( 20585627)
Protein-Protein Interactions		106 interactors: ADAMTSL5 AMMECR1 APOL6 AQP1 ARNT2 ASPSCR1 C19orf66 C6orf165 CATSPER1 CCDC26 CHCHD2 CLEC18A COL8A1 CPNE7 CREB5 CST2 CTSB CXCL16 CYP2S1 DGCR6 DIP2A DLK2 DNPEP DSCR8 EIF4E2 FAH FAM124B FARS2 FBLN1 FBXW5 FHL3 FKBP1B FLNA FRS3 GATA2 GIP GLRX3 GMCL1P1 GNE GNMT GOLGA8EP HGF HOXA1 KIF1A KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2D LCE3C LCE3E LCE4A LGALS14 LINC00671 LMO1 LMO2 LONRF1 LRRC29 MAPKBP1 MID2 MORN3 MVP NATD1 NMUR2 NTF4 NTN4 OLFM3 PID1 PIN1 PLSCR1 PRKAB2 PTGER3 RAB2B RCHY1 RHOJ SALL2 SLC23A1 SLC6A20 SMARCC1 SORBS3 SPATA8 SPINK2 SPRY2 STK16 SUSD6 TAPBPL TCEA2 TMEM150A TMSB4XP6 TOP3B TRIM42 TRIP6 TSSK3 TUBGCP4 ZNF417 ZNF587	19 interactors: ADAMTSL4 HOXA1 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 MDFI NOTCH2NL RGS20 SPRY2
Entrez ID		54507	353145
HPRD ID		18237	13975
Ensembl ID		ENSG00000143382	ENSG00000185966
Uniprot IDs		F8WAD0 Q6UY14 Q9UFG7	Q5T5B0
PDB IDs
Enriched GO Terms of Interacting Partners?		Multicellular Organismal Development Keratinization Organ Development Developmental Process Keratinocyte Differentiation System Development Anatomical Structure Development Epidermis Development Tissue Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Epidermal Cell Differentiation Sensory Organ Development Response To Organic Substance Organic Anion Transport Positive Regulation Of Neuron Projection Regeneration Regulation Of Transcription From RNA Polymerase II Promoter Epithelium Development Cellular Response To Thyroid Hormone Stimulus MRNA Transcription From RNA Polymerase II Promoter Skin Development Positive Regulation Of Transcription, DNA-templated Transepithelial Transport Semicircular Canal Development Positive Regulation Of Gene Expression Regulation Of Branching Involved In Salivary Gland Morphogenesis MRNA Transcription Response To Thyroid Hormone Negative Regulation Of Hydrolase Activity Cell Differentiation Negative Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process	Embryonic Organ Morphogenesis Embryonic Organ Development Optokinetic Behavior Abducens Nerve Formation Inner Ear Morphogenesis Embryonic Skeletal System Morphogenesis Ear Morphogenesis Facial Nucleus Development Embryonic Morphogenesis Rhombomere 4 Development Semicircular Canal Formation Sensory Perception Of Sound Embryonic Skeletal System Development Rhombomere 3 Development Rhombomere 5 Development Sensory Perception Of Mechanical Stimulus Inner Ear Development Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Ear Development Lung Growth Organ Morphogenesis Embryonic Neurocranium Morphogenesis Skeletal System Morphogenesis Regulation Of Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Signal Transduction Outer Ear Morphogenesis Regulation Of MAP Kinase Activity Semicircular Canal Morphogenesis Protein O-linked Fucosylation Rhombomere Development Embryo Development Facial Nerve Structural Organization Pons Development Negative Regulation Of Signaling Facial Nerve Morphogenesis Bud Elongation Involved In Lung Branching Semicircular Canal Development Trophoblast Giant Cell Differentiation Negative Regulation Of Peptidyl-threonine Phosphorylation Parasympathetic Nervous System Development Negative Regulation Of Ras GTPase Activity Anatomical Structure Arrangement Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Cytoplasmic Sequestering Of Transcription Factor Dorsal/ventral Axis Specification Tube Morphogenesis Positive Regulation Of MAPK Cascade Cytoplasmic Sequestering Of Protein Positive Regulation Of Protein Kinase Activity
Tagcloud ?		abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii
Tagcloud (Difference) ?		abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii
Tagcloud (Intersection) ?