ADAMTSL4 and MVP

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		ADAMTSL4	MVP
Gene Name		ADAMTS-like 4	major vault protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Interstitial Matrix Endoplasmic Reticulum Lumen	Nucleus Nuclear Pore Cytoplasm Cytoskeleton Membrane Ribonucleoprotein Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protease Binding Metalloendopeptidase Activity Protein Binding	Protein Binding Protein Kinase Binding Protein Phosphatase Binding
	Biological Process	Protein O-linked Glycosylation Proteolysis Apoptotic Process Extracellular Matrix Organization Protein O-linked Fucosylation Positive Regulation Of Apoptotic Process Post-translational Protein Modification Cellular Protein Metabolic Process	Cell Proliferation Protein Transport Negative Regulation Of Signaling Negative Regulation Of Protein Autophosphorylation ERBB Signaling Pathway MRNA Transport Negative Regulation Of Protein Tyrosine Kinase Activity Protein Activation Cascade
Pathways		Post-translational protein modification O-glycosylation of TSR domain-containing proteins O-linked glycosylation
Drugs
Diseases
GWAS		Rhegmatogenous retinal detachment ( 23585552)
Protein-Protein Interactions		106 interactors: ADAMTSL5 AMMECR1 APOL6 AQP1 ARNT2 ASPSCR1 C19orf66 C6orf165 CATSPER1 CCDC26 CHCHD2 CLEC18A COL8A1 CPNE7 CREB5 CST2 CTSB CXCL16 CYP2S1 DGCR6 DIP2A DLK2 DNPEP DSCR8 EIF4E2 FAH FAM124B FARS2 FBLN1 FBXW5 FHL3 FKBP1B FLNA FRS3 GATA2 GIP GLRX3 GMCL1P1 GNE GNMT GOLGA8EP HGF HOXA1 KIF1A KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2D LCE3C LCE3E LCE4A LGALS14 LINC00671 LMO1 LMO2 LONRF1 LRRC29 MAPKBP1 MID2 MORN3 MVP NATD1 NMUR2 NTF4 NTN4 OLFM3 PID1 PIN1 PLSCR1 PRKAB2 PTGER3 RAB2B RCHY1 RHOJ SALL2 SLC23A1 SLC6A20 SMARCC1 SORBS3 SPATA8 SPINK2 SPRY2 STK16 SUSD6 TAPBPL TCEA2 TMEM150A TMSB4XP6 TOP3B TRIM42 TRIP6 TSSK3 TUBGCP4 ZNF417 ZNF587	57 interactors: ADAMTSL4 AES BANP BZRAP1 C1orf94 CALCOCO2 CAMK2B CCDC36 CKAP4 CYTB DISC1 DLX2 EPHX2 ESR1 FAM154A FAM46C GIT2 GOLGA2 HP KCTD9 KPNA2 KPNA3 MDFI MEOX1 MEOX2 MID2 MKL1 NNT NOTCH2NL OBFC1 PARP4 PIH1D2 PLSCR1 POT1 PSTPIP1 PTEN PTPN11 RAB3IP RBPMS REL RHOXF2 RIMBP3 RNF111 SERTAD1 SKIL SLC2A4 TCF4 TFCP2 TP53 TRAF2 TRIM27 TRIM42 TRIP13 TRIP6 VAC14 ZBTB32 ZMIZ2
Entrez ID		54507	9961
HPRD ID		18237	05475
Ensembl ID		ENSG00000143382	ENSG00000013364
Uniprot IDs		F8WAD0 Q6UY14 Q9UFG7	B4DP93 Q14764
PDB IDs			1Y7X
Enriched GO Terms of Interacting Partners?		Multicellular Organismal Development Keratinization Organ Development Developmental Process Keratinocyte Differentiation System Development Anatomical Structure Development Epidermis Development Tissue Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Epidermal Cell Differentiation Sensory Organ Development Response To Organic Substance Organic Anion Transport Positive Regulation Of Neuron Projection Regeneration Regulation Of Transcription From RNA Polymerase II Promoter Epithelium Development Cellular Response To Thyroid Hormone Stimulus MRNA Transcription From RNA Polymerase II Promoter Skin Development Positive Regulation Of Transcription, DNA-templated Transepithelial Transport Semicircular Canal Development Positive Regulation Of Gene Expression Regulation Of Branching Involved In Salivary Gland Morphogenesis MRNA Transcription Response To Thyroid Hormone Negative Regulation Of Hydrolase Activity Cell Differentiation Negative Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process	Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Regulation Of Nucleic Acid-templated Transcription Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Signaling Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Response To Cytokine RNA Metabolic Process Defense Response Positive Regulation Of Cellular Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Response To Stress Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Immune System Process Nitrogen Compound Metabolic Process Negative Regulation Of Signaling Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Organic Substance Positive Regulation Of Apoptotic Process Protein Localization To Nucleus Positive Regulation Of Programmed Cell Death Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Regulation Of Intracellular Signal Transduction Cellular Metabolic Process Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process Regulation Of Catalytic Activity
Tagcloud ?		abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii	afp bleomycin bronchogenic cap chance cisplatin cooperative crs cyclophosphamide doxorubicin eastern ecog efficacious entered est evaluable fluorouracil institution lethal mitomycin modest nscbc october oncology prs regimens shrinkage threatening vinblastine
Tagcloud (Difference) ?		abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii	afp bleomycin bronchogenic cap chance cisplatin cooperative crs cyclophosphamide doxorubicin eastern ecog efficacious entered est evaluable fluorouracil institution lethal mitomycin modest nscbc october oncology prs regimens shrinkage threatening vinblastine
Tagcloud (Intersection) ?