Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
SORBS3 and EFS
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
HPRD
(two hybrid)
SORBS3
EFS
Gene Name
sorbin and SH3 domain containing 3
embryonal Fyn-associated substrate
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Cytoskeleton
Focal Adhesion
Cytoplasm
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
Transcription Factor Binding
Vinculin Binding
SH3 Domain Binding
Protein Domain Specific Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Muscle Contraction
Actin Filament Organization
Cell Adhesion
Cell-substrate Adhesion
Positive Regulation Of MAPK Cascade
Positive Regulation Of Cytoskeleton Organization
Positive Regulation Of Stress Fiber Assembly
Cell Adhesion
Intracellular Signal Transduction
Pathways
Smooth Muscle Contraction
Drugs
Diseases
GWAS
HIV-1 control (
20205591
)
Protein-Protein Interactions
46 interactors:
ABL1
ADAM15
ADAMTSL4
AKT1
ARNT2
CBLB
CPNE2
CPSF7
DDX17
DIP2A
DLG5
DMRTB1
DVL2
EFS
EIF3H
FAM154A
FASLG
FLOT1
HNRNPK
HNRNPUL1
INPPL1
KIAA0408
KIAA1217
MAPK1
MAPK3
NCKIPSD
NOTCH3
PAK1
PAK2
PAK7
RBMX
SAFB2
SH2D4A
SOCS7
SRCIN1
TBC1D22B
TRIM23
TRIM27
TRIM41
VARS2
VPS37B
VPS37C
ZBED1
ZBTB25
ZBTB7B
ZC4H2
21 interactors:
ABI2
APP
BCAR1
BLK
CRK
FYN
LYST
NPAS2
NUP155
OSTF1
PTK2
PTK2B
PTPN12
SH2D3C
SORBS2
SORBS3
SRC
TRAPPC6A
TSSK1B
UBC
ZNF417
Entrez ID
10174
10278
HPRD ID
11535
09932
Ensembl ID
ENSG00000120896
ENSG00000100842
Uniprot IDs
O60504
B4DJ56
O43281
PDB IDs
2CT3
2DLM
2NWM
2YUP
Enriched GO Terms of Interacting Partners
?
Gene Expression
Regulation Of Cellular Amino Acid Metabolic Process
Transcription, DNA-templated
Regulation Of Cellular Ketone Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
RNA Biosynthetic Process
Regulation Of Metabolic Process
Fc Receptor Signaling Pathway
Regulation Of Protein Kinase Activity
Regulation Of Kinase Activity
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Protein Metabolic Process
Regulation Of Cellular Process
Negative Regulation Of Protein Kinase Activity
Intracellular Signal Transduction
Negative Regulation Of Kinase Activity
Regulation Of Protein Metabolic Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
RNA Metabolic Process
Regulation Of Protein Tyrosine Kinase Activity
Biosynthetic Process
Regulation Of Gene Expression
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Innate Immune Response
Response To Insulin
Immune Response
Regulation Of Protein Phosphorylation
Negative Regulation Of Transferase Activity
Response To Epidermal Growth Factor
Immune Response-regulating Signaling Pathway
Positive Regulation Of Protein Kinase Activity
Regulation Of Golgi Inheritance
Negative Regulation Of Protein Phosphorylation
Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Kinase Activity
Regulation Of Cellular Protein Metabolic Process
Caveolin-mediated Endocytosis
Cellular Response To Insulin Stimulus
Cell Morphogenesis Involved In Differentiation
Protein Autophosphorylation
Positive Regulation Of Protein Phosphorylation
Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Protein Tyrosine Kinase Activity
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Phosphorus Metabolic Process
Peptidyl-tyrosine Autophosphorylation
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Innate Immune Response
Platelet Activation
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Signal Complex Assembly
Positive Regulation Of Immune System Process
Blood Coagulation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Hemostasis
Cell Activation
Peptidyl-tyrosine Phosphorylation
Immune Response-regulating Signaling Pathway
Actin Filament Organization
Cellular Response To Peptide Hormone Stimulus
Cell Migration
Cellular Response To Peptide
Locomotion
Regulation Of Body Fluid Levels
Cell Motility
Enzyme Linked Receptor Protein Signaling Pathway
Wound Healing
Protein Autophosphorylation
Immune Response
Regulation Of Immune System Process
Positive Regulation Of Immune Response
Defense Response
Phosphate-containing Compound Metabolic Process
Neurotrophin TRK Receptor Signaling Pathway
Phosphorylation
Neurotrophin Signaling Pathway
Positive Regulation Of Phosphatidylinositol 3-kinase Activity
Response To Wounding
Ephrin Receptor Signaling Pathway
Response To Peptide Hormone
Movement Of Cell Or Subcellular Component
Cellular Response To Organonitrogen Compound
Response To Peptide
Fc Receptor Signaling Pathway
Positive Regulation Of Intracellular Signal Transduction
Cell Adhesion
Response To Organonitrogen Compound
Integrin-mediated Signaling Pathway
Immune System Process
Positive Regulation Of Signal Transduction
Regulation Of Immune Response
Antigen Receptor-mediated Signaling Pathway
Tagcloud
?
alg
aplastic
austria
beginning
bmt
cessation
cr
csa
cured
cyclosporin
evaluable
germany
immunosuppressive
ist
mentioned
microliter
nonresponders
pmn
probability
pts
relapsed
relapses
resp
saa
sibling
suffered
tapering
transfusions
vsaa
Tagcloud (Difference)
?
alg
aplastic
austria
beginning
bmt
cessation
cr
csa
cured
cyclosporin
evaluable
germany
immunosuppressive
ist
mentioned
microliter
nonresponders
pmn
probability
pts
relapsed
relapses
resp
saa
sibling
suffered
tapering
transfusions
vsaa
Tagcloud (Intersection)
?