ADAMTSL4 and C19orf66

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ADAMTSL4	C19orf66
Gene Name		ADAMTS-like 4	chromosome 19 open reading frame 66
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Interstitial Matrix Endoplasmic Reticulum Lumen
	Molecular Function	Protease Binding Metalloendopeptidase Activity Protein Binding
	Biological Process	Protein O-linked Glycosylation Proteolysis Apoptotic Process Extracellular Matrix Organization Protein O-linked Fucosylation Positive Regulation Of Apoptotic Process Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Post-translational protein modification O-glycosylation of TSR domain-containing proteins O-linked glycosylation
Drugs
Diseases
GWAS		Rhegmatogenous retinal detachment ( 23585552)
Protein-Protein Interactions		106 interactors: ADAMTSL5 AMMECR1 APOL6 AQP1 ARNT2 ASPSCR1 C19orf66 C6orf165 CATSPER1 CCDC26 CHCHD2 CLEC18A COL8A1 CPNE7 CREB5 CST2 CTSB CXCL16 CYP2S1 DGCR6 DIP2A DLK2 DNPEP DSCR8 EIF4E2 FAH FAM124B FARS2 FBLN1 FBXW5 FHL3 FKBP1B FLNA FRS3 GATA2 GIP GLRX3 GMCL1P1 GNE GNMT GOLGA8EP HGF HOXA1 KIF1A KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2D LCE3C LCE3E LCE4A LGALS14 LINC00671 LMO1 LMO2 LONRF1 LRRC29 MAPKBP1 MID2 MORN3 MVP NATD1 NMUR2 NTF4 NTN4 OLFM3 PID1 PIN1 PLSCR1 PRKAB2 PTGER3 RAB2B RCHY1 RHOJ SALL2 SLC23A1 SLC6A20 SMARCC1 SORBS3 SPATA8 SPINK2 SPRY2 STK16 SUSD6 TAPBPL TCEA2 TMEM150A TMSB4XP6 TOP3B TRIM42 TRIP6 TSSK3 TUBGCP4 ZNF417 ZNF587	32 interactors: ADAMTSL4 CADPS CCDC136 DRICH1 DTNBP1 IKZF1 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-4 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 LZTS2 MAGEA1 MDFI MEOX2 MID2 MTUS2 NOTCH2NL PDE4DIP SPRY2 SSX2IP TCF4 TERF1 TNS2 TRAF1
Entrez ID		54507	55337
HPRD ID		18237	07747
Ensembl ID		ENSG00000143382	ENSG00000130813
Uniprot IDs		F8WAD0 Q6UY14 Q9UFG7	Q9NUL5
PDB IDs
Enriched GO Terms of Interacting Partners?		Multicellular Organismal Development Keratinization Organ Development Developmental Process Keratinocyte Differentiation System Development Anatomical Structure Development Epidermis Development Tissue Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Epidermal Cell Differentiation Sensory Organ Development Response To Organic Substance Organic Anion Transport Positive Regulation Of Neuron Projection Regeneration Regulation Of Transcription From RNA Polymerase II Promoter Epithelium Development Cellular Response To Thyroid Hormone Stimulus MRNA Transcription From RNA Polymerase II Promoter Skin Development Positive Regulation Of Transcription, DNA-templated Transepithelial Transport Semicircular Canal Development Positive Regulation Of Gene Expression Regulation Of Branching Involved In Salivary Gland Morphogenesis MRNA Transcription Response To Thyroid Hormone Negative Regulation Of Hydrolase Activity Cell Differentiation Negative Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process	Regulation Of Signal Transduction Developmental Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Signaling Cellular Localization Organelle Localization Cellular Component Assembly Negative Regulation Of Biosynthetic Process Negative Regulation Of Wnt Signaling Pathway Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Vesicle Localization Protein Complex Assembly Positive Regulation Of Neutrophil Differentiation Negative Regulation Of Signal Transduction Cellular Macromolecular Complex Assembly Anatomical Structure Development Organelle Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Wnt Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Protein Kinase B Signaling Embryonic Organ Morphogenesis Negative Regulation Of Protein Localization To Nucleus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Establishment Of Organelle Localization Cellular Protein Complex Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Microtubule-based Process Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Telomeric Loop Formation Age-dependent Telomere Shortening Cell Cycle Establishment Of Localization In Cell Positive Regulation Of Intracellular Signal Transduction Telomere Maintenance Via Telomere Shortening Catecholamine Secretion Maintenance Of DNA Repeat Elements Negative Regulation Of Cellular Response To Growth Factor Stimulus Synaptic Vesicle Transport Multicellular Organism Growth Regulation Of Apoptotic Process Regulation Of Cellular Process Multicellular Organismal Development Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Protein Kinase B Signaling
Tagcloud ?		abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii
Tagcloud (Difference) ?		abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii
Tagcloud (Intersection) ?