SORBS3 and ZBED1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SORBS3	ZBED1
Gene Name		sorbin and SH3 domain containing 3	zinc finger, BED-type containing 1
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Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Focal Adhesion	Nuclear Chromosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Transcription Factor Binding Vinculin Binding	DNA Binding Transposase Activity Metal Ion Binding Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Muscle Contraction Actin Filament Organization Cell Adhesion Cell-substrate Adhesion Positive Regulation Of MAPK Cascade Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Stress Fiber Assembly	Metabolic Process
Pathways		Smooth Muscle Contraction
Drugs
Diseases
GWAS		HIV-1 control ( 20205591)
Protein-Protein Interactions		46 interactors: ABL1 ADAM15 ADAMTSL4 AKT1 ARNT2 CBLB CPNE2 CPSF7 DDX17 DIP2A DLG5 DMRTB1 DVL2 EFS EIF3H FAM154A FASLG FLOT1 HNRNPK HNRNPUL1 INPPL1 KIAA0408 KIAA1217 MAPK1 MAPK3 NCKIPSD NOTCH3 PAK1 PAK2 PAK7 RBMX SAFB2 SH2D4A SOCS7 SRCIN1 TBC1D22B TRIM23 TRIM27 TRIM41 VARS2 VPS37B VPS37C ZBED1 ZBTB25 ZBTB7B ZC4H2	25 interactors: AMOTL2 ATRX C1orf109 DGCR6 FABP4 FANCG GPN1 GPSM1 KLHL40 LRRC20 NIF3L1 NIP7 NUDT18 PIAS2 PRKAA1 PRKAR1A PSAP RENBP SORBS3 SPEF1 SSX2 TRAPPC2B TTR UBE2I UCHL5
Entrez ID		10174	9189
HPRD ID		11535	02170
Ensembl ID		ENSG00000120896	ENSG00000214717
Uniprot IDs		O60504	O96006
PDB IDs		2CT3 2DLM 2NWM 2YUP	2CT5
Enriched GO Terms of Interacting Partners?		Gene Expression Regulation Of Cellular Amino Acid Metabolic Process Transcription, DNA-templated Regulation Of Cellular Ketone Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Biosynthetic Process Regulation Of Metabolic Process Fc Receptor Signaling Pathway Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Process Negative Regulation Of Protein Kinase Activity Intracellular Signal Transduction Negative Regulation Of Kinase Activity Regulation Of Protein Metabolic Process Immune Response-regulating Cell Surface Receptor Signaling Pathway RNA Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Biosynthetic Process Regulation Of Gene Expression Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Innate Immune Response Response To Insulin Immune Response Regulation Of Protein Phosphorylation Negative Regulation Of Transferase Activity Response To Epidermal Growth Factor Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Kinase Activity Regulation Of Golgi Inheritance Negative Regulation Of Protein Phosphorylation Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Kinase Activity Regulation Of Cellular Protein Metabolic Process Caveolin-mediated Endocytosis Cellular Response To Insulin Stimulus Cell Morphogenesis Involved In Differentiation Protein Autophosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Tyrosine Kinase Activity Regulation Of Nitrogen Compound Metabolic Process Regulation Of Phosphorus Metabolic Process	Protein Sumoylation Negative Regulation Of Cellular Metabolic Process Regulation Of Catalytic Activity DGDP Catabolic Process DADP Catabolic Process GDP Catabolic Process Negative Regulation Of Glucosylceramide Biosynthetic Process Negative Regulation Of Telomeric RNA Transcription From RNA Pol II Promoter Cold Acclimation Positive Regulation Of SUMO Transferase Activity Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Skeletal Muscle Fiber Differentiation 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process N-acetylmannosamine Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Dihydrobiopterin Metabolic Process Negative Regulation Of Glucose Import In Response To Insulin Stimulus Cellular Response To Hydroxyurea Regulation Of RNA Metabolic Process Organ Growth Small Molecule Metabolic Process Response To Camptothecin N-acetylneuraminate Catabolic Process
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