ADAMTSL4 and ATG9A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ADAMTSL4	ATG9A
Description		ADAMTS like 4	autophagy related 9A
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Interstitial Matrix Endoplasmic Reticulum Lumen Extracellular Matrix	Golgi Membrane Phagophore Assembly Site Autophagosome Membrane Cytoplasm Mitochondrion Endosome Late Endosome Autophagosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Membrane Cytoplasmic Vesicle Late Endosome Membrane Mitochondrial Membrane Phagophore Assembly Site Membrane Recycling Endosome Recycling Endosome Membrane Synaptic Membrane
	Molecular Function	Protease Binding Protein Binding Identical Protein Binding	Protein Binding Phospholipid Scramblase Activity
	Biological Process	Epithelial Cell Development Apoptotic Process Extracellular Matrix Organization Positive Regulation Of Apoptotic Process Pigment Cell Development	Autophagosome Assembly Mitophagy Lipid Transport Autophagy Negative Regulation Of Macrophage Cytokine Production Plasma Membrane Phospholipid Scrambling Negative Regulation Of Interferon-beta Production Protein Localization To Golgi Apparatus Protein Localization To Phagophore Assembly Site Piecemeal Microautophagy Of The Nucleus Innate Immune Response Bone Morphogenesis Reticulophagy Programmed Necrotic Cell Death
Pathways		Defective B3GALTL causes PpS O-glycosylation of TSR domain-containing proteins	Macroautophagy PINK1-PRKN Mediated Mitophagy
Drugs
Diseases		Ectopia lentis
GWAS		Appendicular lean mass ( 33097823) Asthma ( 32296059) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Migraine ( 27322543) Refractive error ( 32231278) Rhegmatogenous retinal detachment ( 23585552) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		212 interacting genes: ADAM12 ADAMTSL5 ALPP AMMECR1 APOL6 AQP1 ARNT2 ASPSCR1 ATG9A BAG4 BANF2 BOLA2 BOLA2B BRME1 CATSPER1 CBX3 CCDC26 CFAP206 CHCHD2 CHERP CHIC2 CHRD CHRNG CLEC18A COL8A1 CPNE7 CREB5 CST2 CTSB CXCL16 CYP2S1 CYSRT1 DGCR6 DGCR6L DIP2A DLK2 DNPEP DSCR8 EFEMP2 EIF4E2 EPDR1 ERCC3 EXOSC5 FAH FAM124B FARS2 FBLN1 FBXL9P FBXO17 FBXW5 FHL3 FKBP1B FLNA FRS3 FXR1 GATA2 GIP GLRX3 GLYCTK GMCL2 GNE GNG13 GNMT GOLGA8EP GSTP1 GUCD1 HEXIM2 HGF HNRNPLL HOXA1 HOXC8 HSD3B7 INS IP6K1 ITGB2 ITGB4 JOSD1 KCTD7 KCTD9 KIF1A KLHL38 KRTAP1-1 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP19-2 KRTAP21-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 LCE1A LCE1B LCE1C LCE1D LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LGALS14 LHX4 LINC00671 LMO1 LMO2 LMO4 LNX1 LONRF1 LRFN4 MAGOHB MAPKBP1 MGAT5B MID2 MKRN3 MORN3 MVP MYLIP MYO15B NATD1 NBPF19 NEK8 NFKBID NMUR2 NOTCH2NLA NR4A3 NTAQ1 NTF4 NTN4 NUFIP2 OLFM3 OTX1 PCSK5 PID1 PIN1 PKN1 PLSCR1 PLSCR4 POLD1 POLR1C POU4F2 PRKAB2 PRR19 PTGER3 PTPMT1 QPRT R3HDM2 RAB2B RCHY1 RGL2 RHOJ RPS19BP1 RUNX1T1 SALL2 SCNM1 SHFL SLC13A5 SLC23A1 SLC6A20 SLIT1 SMARCC1 SORBS3 SPATA8 SPINK2 SPRY1 SPRY2 STK16 SUSD6 TAPBPL TCEA2 TFAP2D TGFB1 THAP6 TMEM150A TMSB4XP6 TOP3B TRIM42 TRIM55 TRIM63 TRIP6 TSSK3 TUBGCP4 USP21 VASN VENTX VWC2 ZFHX2 ZNF330 ZNF414 ZNF417 ZNF587	48 interacting genes: ADAMTSL4 ANKRD10 AP2M1 CERCAM CFAP68 CIB4 CYSRT1 ETHE1 HDHD3 KLHL20 KPRP KRT31 KRT33B KRT34 KRT35 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP11-1 KRTAP13-3 KRTAP19-1 KRTAP3-2 KRTAP3-3 KRTAP4-2 KRTAP5-9 KRTAP6-2 KRTAP8-1 KRTAP9-2 LONRF1 MAPK6 MEOX1 MEOX2 MGAT5B NBPF19 NDUFB7 NOTCH2NLA OXER1 REL SRC SRCAP TBK1 TCF4 TRIM42 UBE3A YPEL3 ZBTB42 ZNF581 ZNF620
Entrez ID		54507	79065
HPRD ID		18237	07979
Ensembl ID		ENSG00000143382	ENSG00000198925
Uniprot IDs		A0A669KBE7 B7ZMJ3 Q6UY14	Q7Z3C6
PDB IDs			6WQZ 6WR4 7JLO 7JLP 7JLQ 8KBZ 8KC3 8Y1L
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratinization Keratin Filament Epidermis Development Protein Binding Tissue Development Identical Protein Binding Hair Cycle	Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Structural Molecule Activity Epidermis Development Intermediate Filament Organization Somite Specification Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process
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