ADAMTSL4 and GIP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ADAMTSL4	GIP
Gene Name		ADAMTS-like 4	gastric inhibitory polypeptide
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Interstitial Matrix Endoplasmic Reticulum Lumen	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule Lumen Neuronal Cell Body
	Molecular Function	Protease Binding Metalloendopeptidase Activity Protein Binding	Hormone Activity
	Biological Process	Protein O-linked Glycosylation Proteolysis Apoptotic Process Extracellular Matrix Organization Protein O-linked Fucosylation Positive Regulation Of Apoptotic Process Post-translational Protein Modification Cellular Protein Metabolic Process	Signal Transduction Female Pregnancy Memory Adult Locomotory Behavior Response To Glucose Response To Selenium Ion Positive Regulation Of Glucose Transport Response To Organic Cyclic Compound Sensory Perception Of Pain Endocrine Pancreas Development Positive Regulation Of Insulin Secretion Response To Lipid Exploration Behavior Response To Drug Response To Starvation Response To Amino Acid Response To Peptide Hormone Positive Regulation Of CAMP-mediated Signaling Cellular Protein Metabolic Process Response To Axon Injury Regulation Of Insulin Secretion Digestive System Development Long-term Synaptic Potentiation Positive Regulation Of Glucagon Secretion Triglyceride Homeostasis
Pathways		Post-translational protein modification O-glycosylation of TSR domain-containing proteins O-linked glycosylation	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR G alpha (s) signalling events Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Glucagon-type ligand receptors GPCR ligand binding Metabolic disorders of biological oxidation enzymes Peptide hormone metabolism GPCR downstream signaling Class B/2 (Secretin family receptors) Incretin synthesis, secretion, and inactivation
Drugs
Diseases
GWAS		Rhegmatogenous retinal detachment ( 23585552)	Coronary heart disease ( 21378990)
Protein-Protein Interactions		106 interactors: ADAMTSL5 AMMECR1 APOL6 AQP1 ARNT2 ASPSCR1 C19orf66 C6orf165 CATSPER1 CCDC26 CHCHD2 CLEC18A COL8A1 CPNE7 CREB5 CST2 CTSB CXCL16 CYP2S1 DGCR6 DIP2A DLK2 DNPEP DSCR8 EIF4E2 FAH FAM124B FARS2 FBLN1 FBXW5 FHL3 FKBP1B FLNA FRS3 GATA2 GIP GLRX3 GMCL1P1 GNE GNMT GOLGA8EP HGF HOXA1 KIF1A KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2D LCE3C LCE3E LCE4A LGALS14 LINC00671 LMO1 LMO2 LONRF1 LRRC29 MAPKBP1 MID2 MORN3 MVP NATD1 NMUR2 NTF4 NTN4 OLFM3 PID1 PIN1 PLSCR1 PRKAB2 PTGER3 RAB2B RCHY1 RHOJ SALL2 SLC23A1 SLC6A20 SMARCC1 SORBS3 SPATA8 SPINK2 SPRY2 STK16 SUSD6 TAPBPL TCEA2 TMEM150A TMSB4XP6 TOP3B TRIM42 TRIP6 TSSK3 TUBGCP4 ZNF417 ZNF587	5 interactors: ADAMTSL4 GIPR KRTAP10-3 NOTCH2NL SGTA
Entrez ID		54507	2695
HPRD ID		18237	15925
Ensembl ID		ENSG00000143382	ENSG00000159224
Uniprot IDs		F8WAD0 Q6UY14 Q9UFG7	P09681
PDB IDs			1T5Q 2B4N 2L70 2L71 2OBU 2QKH
Enriched GO Terms of Interacting Partners?		Multicellular Organismal Development Keratinization Organ Development Developmental Process Keratinocyte Differentiation System Development Anatomical Structure Development Epidermis Development Tissue Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Epidermal Cell Differentiation Sensory Organ Development Response To Organic Substance Organic Anion Transport Positive Regulation Of Neuron Projection Regeneration Regulation Of Transcription From RNA Polymerase II Promoter Epithelium Development Cellular Response To Thyroid Hormone Stimulus MRNA Transcription From RNA Polymerase II Promoter Skin Development Positive Regulation Of Transcription, DNA-templated Transepithelial Transport Semicircular Canal Development Positive Regulation Of Gene Expression Regulation Of Branching Involved In Salivary Gland Morphogenesis MRNA Transcription Response To Thyroid Hormone Negative Regulation Of Hydrolase Activity Cell Differentiation Negative Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process	Gastric Inhibitory Peptide Signaling Pathway
Tagcloud ?		abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii	32pua aspirated aspiration corp curved cystadenomas cytologic eum eus fg gauge grassau medizin melville negatives ny olympus orangeburg passes pentax pseudocyst resolving rtfna rtfnas staging suspicious technik tomographic unsuccessful
Tagcloud (Difference) ?		abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii	32pua aspirated aspiration corp curved cystadenomas cytologic eum eus fg gauge grassau medizin melville negatives ny olympus orangeburg passes pentax pseudocyst resolving rtfna rtfnas staging suspicious technik tomographic unsuccessful
Tagcloud (Intersection) ?