ADAMTSL4 and NTF4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ADAMTSL4	NTF4
Gene Name		ADAMTS-like 4	neurotrophin 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Interstitial Matrix Endoplasmic Reticulum Lumen	Extracellular Region Endoplasmic Reticulum Lumen Cytoplasmic Membrane-bounded Vesicle
	Molecular Function	Protease Binding Metalloendopeptidase Activity Protein Binding	Neurotrophin P75 Receptor Binding Growth Factor Activity
	Biological Process	Protein O-linked Glycosylation Proteolysis Apoptotic Process Extracellular Matrix Organization Protein O-linked Fucosylation Positive Regulation Of Apoptotic Process Post-translational Protein Modification Cellular Protein Metabolic Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell-cell Signaling Ganglion Mother Cell Fate Determination Long-term Memory Sensory Organ Boundary Specification Adult Locomotory Behavior Epidermis Development Mechanoreceptor Differentiation Negative Regulation Of Neuron Apoptotic Process Regulation Of Neuron Differentiation Neuron Projection Morphogenesis Innervation Taste Bud Development
Pathways		Post-translational protein modification O-glycosylation of TSR domain-containing proteins O-linked glycosylation
Drugs
Diseases
GWAS		Rhegmatogenous retinal detachment ( 23585552)
Protein-Protein Interactions		106 interactors: ADAMTSL5 AMMECR1 APOL6 AQP1 ARNT2 ASPSCR1 C19orf66 C6orf165 CATSPER1 CCDC26 CHCHD2 CLEC18A COL8A1 CPNE7 CREB5 CST2 CTSB CXCL16 CYP2S1 DGCR6 DIP2A DLK2 DNPEP DSCR8 EIF4E2 FAH FAM124B FARS2 FBLN1 FBXW5 FHL3 FKBP1B FLNA FRS3 GATA2 GIP GLRX3 GMCL1P1 GNE GNMT GOLGA8EP HGF HOXA1 KIF1A KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2D LCE3C LCE3E LCE4A LGALS14 LINC00671 LMO1 LMO2 LONRF1 LRRC29 MAPKBP1 MID2 MORN3 MVP NATD1 NMUR2 NTF4 NTN4 OLFM3 PID1 PIN1 PLSCR1 PRKAB2 PTGER3 RAB2B RCHY1 RHOJ SALL2 SLC23A1 SLC6A20 SMARCC1 SORBS3 SPATA8 SPINK2 SPRY2 STK16 SUSD6 TAPBPL TCEA2 TMEM150A TMSB4XP6 TOP3B TRIM42 TRIP6 TSSK3 TUBGCP4 ZNF417 ZNF587	4 interactors: ADAMTSL4 CLIC1 NGFR NTRK2
Entrez ID		54507	4909
HPRD ID		18237	01220
Ensembl ID		ENSG00000143382	ENSG00000225950
Uniprot IDs		F8WAD0 Q6UY14 Q9UFG7	P34130
PDB IDs			1B8M 1B98 1HCF
Enriched GO Terms of Interacting Partners?		Multicellular Organismal Development Keratinization Organ Development Developmental Process Keratinocyte Differentiation System Development Anatomical Structure Development Epidermis Development Tissue Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Epidermal Cell Differentiation Sensory Organ Development Response To Organic Substance Organic Anion Transport Positive Regulation Of Neuron Projection Regeneration Regulation Of Transcription From RNA Polymerase II Promoter Epithelium Development Cellular Response To Thyroid Hormone Stimulus MRNA Transcription From RNA Polymerase II Promoter Skin Development Positive Regulation Of Transcription, DNA-templated Transepithelial Transport Semicircular Canal Development Positive Regulation Of Gene Expression Regulation Of Branching Involved In Salivary Gland Morphogenesis MRNA Transcription Response To Thyroid Hormone Negative Regulation Of Hydrolase Activity Cell Differentiation Negative Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process	Positive Regulation Of Axonogenesis Positive Regulation Of Cell Differentiation Regulation Of Axonogenesis Positive Regulation Of Cell Morphogenesis Involved In Differentiation Circadian Rhythm Negative Regulation Of Hair Follicle Development Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Neurotrophin Signaling Pathway Brain-derived Neurotrophic Factor Receptor Signaling Pathway Negative Regulation Of Hair Cycle Positive Regulation Of Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Cell Projection Organization Regulation Of Apoptotic Process Rhythmic Process Regulation Of Cell Death Regulation Of Cell Differentiation Positive Regulation Of Neuron Differentiation Regulation Of Neuron Projection Development Positive Regulation Of Neurogenesis Protein O-linked Fucosylation Positive Regulation Of Odontogenesis Retinal Rod Cell Development Peripheral Nervous System Neuron Development Calcium-mediated Signaling Using Intracellular Calcium Source Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Negative Regulation Of Anoikis Positive Regulation Of Cell Development Regulation Of Odontogenesis Of Dentin-containing Tooth Membrane Protein Intracellular Domain Proteolysis Regulation Of Hair Follicle Development Regulation Of Anoikis Regulation Of Neuron Differentiation Response To Auditory Stimulus Cellular Response To Growth Factor Stimulus Regulation Of Glucose Import In Response To Insulin Stimulus Positive Regulation Of Apoptotic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Programmed Cell Death Response To Growth Factor Regulation Of Hair Cycle Regulation Of Rac GTPase Activity Positive Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of Cell Death Glutamate Secretion Cellular Response To Nerve Growth Factor Stimulus Anion Transport Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Detection Of Temperature Stimulus
Tagcloud ?		abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii	actin contain cytosolic exclusively filament fractionation germination kim map mature motif mutagenesis ntmek2 ntprof2 p45 pellet phosphorylate pollen predominantly profilin profilins residue sipk speed substrates thought threonine tobacco tube
Tagcloud (Difference) ?		abl baalc bcr cd83 ciita council ctnnd1 e2993 gab1 gli1 hubs il15 irs1 p185bcr p210bcr pilrb ptp4a3 rab21 serpinb9 spp1 spry1 supervised transcriptomic tspan16 ukall underexpressed unsupervised xbp1 xii	actin contain cytosolic exclusively filament fractionation germination kim map mature motif mutagenesis ntmek2 ntprof2 p45 pellet phosphorylate pollen predominantly profilin profilins residue sipk speed substrates thought threonine tobacco tube
Tagcloud (Intersection) ?