KCTD9 and SYT6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		KCTD9	SYT6
Description		potassium channel tetramerization domain containing 9	synaptotagmin 6
Image			No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Exocytic Vesicle Perinuclear Endoplasmic Reticulum
	Molecular Function	Protein Binding Identical Protein Binding Cullin Family Protein Binding	SNARE Binding Protein Binding Calcium-dependent Phospholipid Binding Syntaxin Binding Clathrin Binding Protein Homodimerization Activity Metal Ion Binding Calcium Ion Sensor Activity
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction Protein Homooligomerization	Chemical Synaptic Transmission Vesicle-mediated Transport Regulation Of Calcium Ion-dependent Exocytosis Acrosomal Vesicle Exocytosis
Pathways
Drugs
Diseases
GWAS		Lymphocyte count ( 32888494)	Breast cancer (prognosis) ( 23319801) Obesity-related traits ( 23251661) Refractive error ( 32231278)
Interacting Genes		91 interacting genes: ACTMAP ADAMTSL4 ANKS1A AQP1 ARID5A BANP BLZF1 CARD9 CBX8 CCDC33 CDC37 CDPF1 CFP CRADD DDIT4L DEUP1 EHHADH EPM2AIP1 FAM124B GEM GOLGA6L9 GORASP2 GPANK1 HOXA1 HOXC8 IGFN1 IL16 INCA1 KIF9 KLHL26 KRT31 KRT34 KRT35 KRT40 KRTAP13-2 KRTAP13-3 LNX1 LONRF1 MAD2L2 MBD3L1 MEOX2 MIIP MVP NDUFAB1 NIF3L1 NTAQ1 PDZD4 PFDN5 PICK1 PLOD3 PNKD POF1B PPP1R16B PPP1R18 PRDM6 PRKAA2 PSMA1 PSMB2 RBPMS RFX6 RUSC1 SAXO4 SDCBP SKP1 SLAIN1 SMARCB1 SMUG1 SPATS1 SPG21 SPMIP4 SPMIP6 SPMIP9 STX11 SYT6 TASOR2 TEPSIN TNS2 TRIM27 TRIM32 TRIM42 TRIP6 UNKL USP21 USP54 WDR83 ZBTB25 ZBTB42 ZNF408 ZNF426 ZNF620 ZNF76	30 interacting genes: APP BRCA1 CCDC136 CCDC57 CNTROB DVL3 FXR1 FXR2 GMCL1 GOLGA2 HMBOX1 HOOK2 KANK2 KCTD9 KIF24 KIFC3 KRT40 LMNA LZTS1 MAD1L1 MCC MTUS2 NRXN1 PRKCB TNIP1 TRIM27 TRIM32 TSGA10 ZBTB43 ZBTB8A
Entrez ID		54793	148281
HPRD ID		13772	09654
Ensembl ID		ENSG00000104756	ENSG00000134207
Uniprot IDs		Q7L273	A0A7I2PMW4 I6L9C3 Q5T7P8
PDB IDs		5BXH
Enriched GO Terms of Interacting Partners?		Protein Binding Identical Protein Binding	Identical Protein Binding Centrosome Microtubule-based Process Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Long-term Neuronal Synaptic Plasticity Microtubule Organizing Center Organization Nuclear Pore Localization NMDA Selective Glutamate Receptor Signaling Pathway Presynaptic Modulation Of Chemical Synaptic Transmission Microtubule Binding Positive Regulation Of Long-term Neuronal Synaptic Plasticity Cytoskeleton Regulation Of Cell Projection Organization Regulation Of Organelle Organization Regulation Of Neuronal Synaptic Plasticity Modulation Of Chemical Synaptic Transmission Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Component Organization Organelle Assembly Centriole Acetylcholine Receptor Binding Positive Regulation Of Biosynthetic Process Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Microtubule Negative Regulation Of Viral Process Cytoplasm Negative Regulation Of Viral Transcription Cellular Component Assembly Suppression Of Viral Release By Host Regulation Of Synaptic Plasticity Translation Regulator Activity Negative Regulation Of Signal Transduction Regulation Of Cellular Component Organization Regulation Of Viral Transcription Presynapse Positive Regulation Of RNA Metabolic Process Organelle Organization Regulation Of Cell Projection Assembly Regulation Of Cilium Assembly Protein Binding Negative Regulation Of Signaling Negative Regulation Of Cell Communication Negative Regulation Of Cilium Assembly Centriole Replication Regulation Of Plasma Membrane Bounded Cell Projection Organization Negative Regulation Of Autophagy Positive Regulation Of Gene Expression Regulation Of Presynapse Organization Regulation Of Presynapse Assembly
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