KCTD9 and PPP1R18

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KCTD9	PPP1R18
Description		potassium channel tetramerization domain containing 9	protein phosphatase 1 regulatory subunit 18
Image			No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytoskeleton
	Molecular Function	Protein Binding Identical Protein Binding Cullin Family Protein Binding	Actin Binding Protein Binding Phosphatase Binding
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Lymphocyte count ( 32888494)	Autism spectrum disorder or schizophrenia ( 28540026) Chronic obstructive pulmonary disease ( 33909500) Hemoglobin levels ( 32327693) Lung cancer ( 28604730)
Interacting Genes		91 interacting genes: ACTMAP ADAMTSL4 ANKS1A AQP1 ARID5A BANP BLZF1 CARD9 CBX8 CCDC33 CDC37 CDPF1 CFP CRADD DDIT4L DEUP1 EHHADH EPM2AIP1 FAM124B GEM GOLGA6L9 GORASP2 GPANK1 HOXA1 HOXC8 IGFN1 IL16 INCA1 KIF9 KLHL26 KRT31 KRT34 KRT35 KRT40 KRTAP13-2 KRTAP13-3 LNX1 LONRF1 MAD2L2 MBD3L1 MEOX2 MIIP MVP NDUFAB1 NIF3L1 NTAQ1 PDZD4 PFDN5 PICK1 PLOD3 PNKD POF1B PPP1R16B PPP1R18 PRDM6 PRKAA2 PSMA1 PSMB2 RBPMS RFX6 RUSC1 SAXO4 SDCBP SKP1 SLAIN1 SMARCB1 SMUG1 SPATS1 SPG21 SPMIP4 SPMIP6 SPMIP9 STX11 SYT6 TASOR2 TEPSIN TNS2 TRIM27 TRIM32 TRIM42 TRIP6 UNKL USP21 USP54 WDR83 ZBTB25 ZBTB42 ZNF408 ZNF426 ZNF620 ZNF76	80 interacting genes: ABRA ACTN3 BICD2 CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCDC88B CDR2L CEP70 COG6 DES DZIP1 EIF3L FAM9B FHL5 FSD2 GCC1 GFAP GMCL1 GOLGA2 GOLGA6L9 GOPC GRIPAP1 GTPBP3 HAP1 HOMER3 HOOK2 HSF2BP IKZF3 KASH5 KCTD9 KRT13 KRT15 KRT16 KRT19 KRT27 KRT31 KRT33B KRT34 KRT36 KRT40 LDOC1 LZTS1 LZTS2 MAD1L1 MAPK1 MEOX2 MID2 MRPL38 MTUS2 NACA NEFL PDE4DIP PIBF1 PLEKHF2 PPP1CA PPP1CC PPP1R13B PRPH SORBS3 SPDL1 STX11 TCF4 TEX11 TFIP11 TRAF2 TRIM23 TRIM27 TRIM54 TRIM62 TRIM69 TSC1 TSGA10 VIM VPS52 ZMYND12 ZRANB1
Entrez ID		54793	170954
HPRD ID		13772	11172
Ensembl ID		ENSG00000104756	ENSG00000146112
Uniprot IDs		Q7L273	A0A024RCJ8 A0A0G2JHC2 Q6NYC8
PDB IDs		5BXH
Enriched GO Terms of Interacting Partners?		Protein Binding Identical Protein Binding	Cytoskeleton Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytoskeleton Organization Intermediate Filament Organelle Organization Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis Keratin Filament Structural Constituent Of Cytoskeleton Structural Molecule Activity Protein Binding Identical Protein Binding Intermediate Filament Cytoskeleton Microtubule-based Process Centrosome Morphogenesis Of An Epithelium Microtubule Cytoskeleton Organization Tissue Morphogenesis Cytosol Cytoplasm Microtubule Organizing Center Bergmann Glial Cell Differentiation Epithelial Cell Differentiation Microtubule Organizing Center Organization Negative Regulation Of Viral Transcription Intracellular Transport Developmental Process Regulation Of Viral Transcription Response To Muramyl Dipeptide Cellular Developmental Process Positive Regulation Of Skeletal Muscle Tissue Growth Establishment Of Localization In Cell Developmental Process Involved In Reproduction Establishment Of Protein Localization Dynein Light Intermediate Chain Binding Cytoskeleton-dependent Intracellular Transport Kinetochore Binding Regulation Of Autophagy Cell Differentiation Regulation Of Skeletal Muscle Tissue Growth Z Disc Intracellular Protein Localization Protein Transport Astrocyte Differentiation PTW/PP1 Phosphatase Complex Cellular Localization Organelle Transport Along Microtubule Cellular Response To Muramyl Dipeptide
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