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KCTD9 and MAD2L2
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
KCTD9
MAD2L2
Description
potassium channel tetramerization domain containing 9
mitotic arrest deficient 2 like 2
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Anaphase-promoting Complex
Chromosome
Cytoplasm
Spindle
Cytoskeleton
Zeta DNA Polymerase Complex
Site Of Double-strand Break
Molecular Function
Protein Binding
Identical Protein Binding
Cullin Family Protein Binding
Transcription Corepressor Activity
Protein Binding
JUN Kinase Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Biological Process
Protein Ubiquitination
Intracellular Signal Transduction
Protein Homooligomerization
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Cell Growth
Somatic Diversification Of Immunoglobulins Involved In Immune Response
DNA Repair
Double-strand Break Repair
DNA Damage Response
Actin Filament Organization
Mitotic Spindle Assembly Checkpoint Signaling
Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Transcription By Competitive Promoter Binding
Positive Regulation Of Peptidyl-serine Phosphorylation
Negative Regulation Of Protein Catabolic Process
Error-prone Translesion Synthesis
DNA Damage Response, Signal Transduction Resulting In Transcription
Telomere Maintenance In Response To DNA Damage
Positive Regulation Of Isotype Switching
Positive Regulation Of DNA-templated Transcription
Cell Division
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Ubiquitin Protein Ligase Activity
Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin
Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways
Translesion synthesis by REV1
Translesion synthesis by POLK
Translesion synthesis by POLI
Drugs
Diseases
GWAS
Lymphocyte count (
32888494
)
Arterial stiffness (brachial-femoral pulse wave velocity) (
32790701
)
Visceral adipose tissue adjusted for BMI (
22589738
)
Interacting Genes
91 interacting genes:
ACTMAP
ADAMTSL4
ANKS1A
AQP1
ARID5A
BANP
BLZF1
CARD9
CBX8
CCDC33
CDC37
CDPF1
CFP
CRADD
DDIT4L
DEUP1
EHHADH
EPM2AIP1
FAM124B
GEM
GOLGA6L9
GORASP2
GPANK1
HOXA1
HOXC8
IGFN1
IL16
INCA1
KIF9
KLHL26
KRT31
KRT34
KRT35
KRT40
KRTAP13-2
KRTAP13-3
LNX1
LONRF1
MAD2L2
MBD3L1
MEOX2
MIIP
MVP
NDUFAB1
NIF3L1
NTAQ1
PDZD4
PFDN5
PICK1
PLOD3
PNKD
POF1B
PPP1R16B
PPP1R18
PRDM6
PRKAA2
PSMA1
PSMB2
RBPMS
RFX6
RUSC1
SAXO4
SDCBP
SKP1
SLAIN1
SMARCB1
SMUG1
SPATS1
SPG21
SPMIP4
SPMIP6
SPMIP9
STX11
SYT6
TASOR2
TEPSIN
TNS2
TRIM27
TRIM32
TRIM42
TRIP6
UNKL
USP21
USP54
WDR83
ZBTB25
ZBTB42
ZNF408
ZNF426
ZNF620
ZNF76
47 interacting genes:
ADAM15
ADAM17
ADAM9
CAMK2B
CDC20
CDH1
CIMIP1
DEPDC5
ELK1
FAM217B
FTO
FZR1
GSC2
IKZF1
IKZF3
INCA1
KCTD9
KRT34
MAD2L1
MAD2L1BP
MBD3L1
MYBPC2
PLAGL2
POLDIP2
PPM1B
PRCC
PRR5L
PRRC2A
RAB11FIP4
RBBP6
REL
REV1
REV3L
SFI1
SHLD1
TCF4
THAP6
TRIM27
TRIM54
TRIM7
YPEL3
YY1AP1
ZBED1
ZMYND12
ZNF511
ZNF558
ZNF655
Entrez ID
54793
10459
HPRD ID
13772
07246
Ensembl ID
ENSG00000104756
ENSG00000116670
Uniprot IDs
Q7L273
Q9UI95
PDB IDs
5BXH
3ABD
3ABE
3VU7
4EXT
4GK0
4GK5
5XPT
5XPU
6BC8
6BCD
6BI7
6K07
6K08
6KEA
6KTO
6M7A
6M7B
6NIF
6VE5
6WS0
6WS5
6WW9
6WWA
7L9P
Enriched GO Terms of Interacting Partners
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Protein Binding
Identical Protein Binding
Mitotic Checkpoint Complex
Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Metal Ion Binding
Translesion Synthesis
Metalloendopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process
Protein Binding
Positive Regulation Of Cell Cycle Process
Regulation Of Anaphase-promoting Complex-dependent Catabolic Process
Positive Regulation Of Ubiquitin Protein Ligase Activity
Regulation Of Cell Cycle
DNA Binding
DNA Biosynthetic Process
Postreplication Repair
Error-free Translesion Synthesis
Positive Regulation Of Synapse Maturation
DNA Synthesis Involved In DNA Repair
Anaphase-promoting Complex Binding
Ubiquitin-protein Transferase Activator Activity
Negative Regulation Of Type I Interferon Production
Positive Regulation Of Cell Cycle
Regulation Of Mitotic Cell Cycle Phase Transition
Error-prone Translesion Synthesis
Regulation Of Mitotic Cell Cycle
Ubiquitin Ligase Activator Activity
Positive Regulation Of Mitotic Cell Cycle
Negative Regulation Of Cell Cycle
DNA-binding Transcription Factor Activity
Positive Regulation Of Ubiquitin-protein Transferase Activity
Zinc Ion Binding
Regulation Of Mitotic Sister Chromatid Separation
Regulation Of Nuclear Division
Negative Regulation Of Interferon-beta Production
Positive Regulation Of Catabolic Process
Regulation Of Cell Cycle Process
Negative Regulation Of Cell Cycle Process
Amyloid Precursor Protein Catabolic Process
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Mitotic Metaphase/anaphase Transition
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Chromosome Separation
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Regulation Of Primary Metabolic Process
Regulation Of Cell Cycle Phase Transition
SUMO Transferase Activity
Anaphase-promoting Complex-dependent Catabolic Process
Positive Regulation Of Mitotic Sister Chromatid Separation
Anaphase-promoting Complex
Regulation Of Metabolic Process
Sequence-specific DNA Binding
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Tagcloud (Intersection)
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