ARL6IP1 and NUDT3

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ARL6IP1	NUDT3
Gene Name		ADP-ribosylation factor-like 6 interacting protein 1	nudix (nucleoside diphosphate linked moiety X)-type motif 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Sec61 Translocon Complex Cytosol Membrane Integral Component Of Membrane	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Magnesium Ion Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate Diphosphatase Activity Inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate Diphosphatase Activity Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity Inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase Activity Inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity
	Biological Process	Cotranslational Protein Targeting To Membrane	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process
Pathways			Synthesis of pyrophosphates in the cytosol Inositol phosphate metabolism
Drugs
Diseases
GWAS			Body mass index ( 20935630) Height ( 19893584)
Protein-Protein Interactions		40 interactors: ACSF2 ARL4D ARL6 C12orf10 COL4A3BP DIABLO FAM134C FBXW7 FDFT1 FXR2 GAD2 GOLPH3 GORASP2 HGS HMGCL INPP5K MTERF3 NAPB NDRG4 NUDT3 PAM16 PBX3 RAB33A RTN4 SENP2 SHMT2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX3 SNX4 SPG21 SUCLA2 TFAM TUFM WIPI2 ZFYVE21 ZNF391	36 interactors: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1
Entrez ID		23204	11165
HPRD ID		09641	14849
Ensembl ID		ENSG00000170540
Uniprot IDs		B7Z6S5 F5GXP4 Q15041	O95989
PDB IDs			2FVV 2Q9P
Enriched GO Terms of Interacting Partners?		Protein Transport Establishment Of Protein Localization Protein Localization Cellular Localization Vesicle Organization Establishment Of Localization In Cell Intracellular Transport Organelle Organization Cellular Protein Localization Intracellular Protein Transport Negative Regulation Of Early Endosome To Late Endosome Transport Mitochondrion Organization Regulation Of DNA Endoreduplication Succinate Metabolic Process Regulation Of Early Endosome To Late Endosome Transport Transport Protein Localization To Cilium Regulation Of Protein Catabolic Process Membrane Invagination Endomembrane System Organization Negative Regulation Of Intracellular Transport Cell Projection Assembly Protein Localization To Organelle Vesicle-mediated Transport Negative Regulation Of SREBP Signaling Pathway Succinyl-CoA Pathway Diphosphoinositol Polyphosphate Catabolic Process Posterior Compartment Specification Anterior Compartment Pattern Formation Positive Regulation Of Renal Water Transport Diadenosine Polyphosphate Catabolic Process Intralumenal Vesicle Formation Membrane Organization Localization Within Membrane Protein Localization To Membrane Endoplasmic Reticulum Organization Regulation Of Vesicle-mediated Transport Inositol Phosphate Metabolic Process Negative Regulation Of Protein Transport Lamellipodium Organization Alcohol Catabolic Process Glutamate Decarboxylation To Succinate Negative Regulation Of Triglyceride Biosynthetic Process ER To Golgi Ceramide Transport Uroporphyrinogen III Biosynthetic Process Cell Adhesion Molecule Production Intermembrane Transport Endosomal Transport Protein Targeting Biosynthetic Process	Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Cellular Metabolic Process Protein Targeting Intracellular Transport Protein Localization To Organelle Cellular Localization Cellular Protein Localization Translational Elongation Establishment Of Protein Localization To Organelle Catabolic Process Protein Localization To Membrane Protein Localization Intracellular Protein Transport Viral Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cellular Process Establishment Of Localization In Cell Protein Targeting To ER Cytoplasmic Transport Aromatic Compound Catabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Protein Transport Protein Localization To Endoplasmic Reticulum DNA Strand Elongation Involved In DNA Replication Establishment Of Protein Localization Branching Involved In Mammary Gland Duct Morphogenesis DNA Strand Elongation Translational Termination Membrane Organization Cellular Macromolecule Catabolic Process Nuclear-transcribed MRNA Catabolic Process Metabolic Process MRNA Catabolic Process Transcription Factor TFIIIB Complex Assembly Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Negative Regulation Of Pancreatic A Cell Differentiation Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process Pharyngeal Arch Artery Morphogenesis Lateral Inhibition Positive Regulation Of Protein Import Into Mitochondrial Outer Membrane Negative Regulation Of Chaperone-mediated Protein Folding Mammary Gland Duct Morphogenesis RNA Catabolic Process Cellular Nitrogen Compound Metabolic Process Response To Interleukin-4 Cellular Protein Complex Disassembly Viral Life Cycle
Tagcloud ?		1a 2b 3c 4c cisternae elaborate elucidated envelope er exogenously harboring homology interconnected localizes organelle potency reticulon reticulons shaped shaping sheet sheets suppress suppresses tmem33 transmembrane tubular tubulation tubules
Tagcloud (Difference) ?		1a 2b 3c 4c cisternae elaborate elucidated envelope er exogenously harboring homology interconnected localizes organelle potency reticulon reticulons shaped shaping sheet sheets suppress suppresses tmem33 transmembrane tubular tubulation tubules
Tagcloud (Intersection) ?