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COL7A1 and FN1
Number of citations of the paper that reports this interaction (PMID
9169408
)
24
Data Source:
HPRD
(in vitro)
COL7A1
FN1
Gene Name
collagen, type VII, alpha 1
fibronectin 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Collagen Type VII Trimer
Basement Membrane
Extracellular Space
Endoplasmic Reticulum Lumen
Extracellular Matrix
Extracellular Region
Fibrinogen Complex
Basal Lamina
Extracellular Space
Endoplasmic Reticulum-Golgi Intermediate Compartment
Apical Plasma Membrane
Extracellular Matrix
Platelet Alpha Granule Lumen
Extracellular Vesicular Exosome
Blood Microparticle
Molecular Function
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Identical Protein Binding
Protease Binding
Integrin Binding
Protein Binding
Collagen Binding
Heparin Binding
Peptidase Activator Activity
Biological Process
Cell Adhesion
Epidermis Development
Negative Regulation Of Endopeptidase Activity
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Collagen Catabolic Process
Endodermal Cell Differentiation
Angiogenesis
Platelet Degranulation
Acute-phase Response
Cell-substrate Junction Assembly
Cell Adhesion
Calcium-independent Cell-matrix Adhesion
Blood Coagulation
Regulation Of Cell Shape
Response To Wounding
Positive Regulation Of Peptidase Activity
Peptide Cross-linking
Extracellular Matrix Disassembly
Platelet Activation
Extracellular Matrix Organization
Integrin Activation
Substrate Adhesion-dependent Cell Spreading
Endodermal Cell Differentiation
Positive Regulation Of Axon Extension
Leukocyte Migration
Pathways
Collagen formation
Laminin interactions
Collagen degradation
Anchoring fibril formation
Integrin cell surface interactions
Collagen biosynthesis and modifying enzymes
Degradation of the extracellular matrix
Assembly of collagen fibrils and other multimeric structures
Elastic fibre formation
p130Cas linkage to MAPK signaling for integrins
Integrin alphaIIb beta3 signaling
GRB2:SOS provides linkage to MAPK signaling for Integrins
Non-integrin membrane-ECM interactions
Platelet degranulation
Platelet Aggregation (Plug Formation)
Degradation of the extracellular matrix
Cell surface interactions at the vascular wall
Molecules associated with elastic fibres
Syndecan interactions
ECM proteoglycans
Fibronectin matrix formation
Response to elevated platelet cytosolic Ca2+
Integrin cell surface interactions
Platelet activation, signaling and aggregation
Drugs
Ocriplasmin
Diseases
GWAS
Protein-Protein Interactions
14 interactors:
BMP1
COL1A1
COL4A1
FBXL2
FN1
HSPA8
LAMA1
LAMA5
LAMB3
LAMC2
MMP2
SHKBP1
THBS1
ZC3H7A
96 interactors:
ADAMTS4
AMBP
APCS
ATXN10
ATXN7
C1QA
CD44
CDKN2A
COL13A1
COL1A1
COL1A2
COL2A1
COL4A1
COL4A2
COL4A3
COL4A4
COL4A5
COL4A6
COL6A2
COL7A1
COMP
CRP
CTSD
CXCL12
DCN
DUSP10
EGFR
F13A1
FAM86B3P
FASLG
FBLN1
FBLN2
FST
FSTL3
GALNT6
GRB2
GSN
HGF
HRG
HSPG2
IGFBP3
IGFBP5
ITGA3
ITGA4
ITGA5
ITGA8
ITGB1
ITGB3
ITGB6
ITGB7
KLK3
KPNA2
LACRT
LGALS3BP
LPA
LRG1
LTBP1
MAG
MATN2
MEP1A
MEP1B
MIA
MMP9
MYOC
NOV
NR0B2
NT5E
PELI2
PKD1
PLAT
PLG
PRELP
PRPF40A
RARA
RBL1
REG3A
RPS6KA5
SCGB1A1
SDC2
SKIL
SMAD4
SMAD9
SPARC
STAT5A
TAB1
TAB2
TAC1
TGFBI
TGM2
THBS1
TMPRSS6
TNC
TNFRSF11B
TSHR
UBQLN1
VHL
Entrez ID
1294
2335
HPRD ID
00358
00626
Ensembl ID
ENSG00000114270
ENSG00000115414
Uniprot IDs
Q02388
Q59F16
P02751
Q6MZF4
Q6MZM7
Q6N084
Q9UQS6
PDB IDs
1E88
1E8B
1FBR
1FNA
1FNF
1FNH
1J8K
1O9A
1OWW
1Q38
1QGB
1QO6
1TTF
1TTG
2CG6
2CG7
2CK2
2CKU
2EC3
2FN2
2FNB
2GEE
2H41
2H45
2HA1
2OCF
2RKY
2RKZ
2RL0
3CAL
3EJH
3GXE
3M7P
3MQL
3R8Q
3T1W
3ZRZ
4GH7
4JE4
4JEG
Enriched GO Terms of Interacting Partners
?
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Extracellular Structure Organization
Tissue Development
Blood Vessel Development
Vasculature Development
Cell-substrate Junction Assembly
Anatomical Structure Morphogenesis
Blood Vessel Morphogenesis
Locomotion
Cardiovascular System Development
Movement Of Cell Or Subcellular Component
Anatomical Structure Formation Involved In Morphogenesis
Angiogenesis
Endodermal Cell Differentiation
Cell Morphogenesis Involved In Differentiation
Anatomical Structure Development
Retinal Blood Vessel Morphogenesis
Cell Junction Assembly
Endoderm Formation
Cellular Response To Amino Acid Stimulus
Developmental Process
Collagen Catabolic Process
Organ Morphogenesis
Intramembranous Ossification
Collagen Metabolic Process
Cell Morphogenesis
Cell Differentiation
Multicellular Organismal Macromolecule Metabolic Process
Skeletal System Morphogenesis
Bone Trabecula Formation
Endoderm Development
Multicellular Organismal Metabolic Process
Multicellular Organismal Development
Cell Adhesion
Retina Vasculature Morphogenesis In Camera-type Eye
Hemidesmosome Assembly
Response To Amino Acid
Bone Trabecula Morphogenesis
Axon Guidance
Formation Of Primary Germ Layer
System Development
Cell Projection Morphogenesis
Cell Part Morphogenesis
Retina Vasculature Development In Camera-type Eye
Morphogenesis Of A Polarized Epithelium
Cellular Response To Acid Chemical
Branching Involved In Salivary Gland Morphogenesis
Gastrulation
Platelet Activation
Extracellular Matrix Organization
Extracellular Structure Organization
Extracellular Matrix Disassembly
Developmental Process
Multicellular Organismal Development
Anatomical Structure Morphogenesis
System Development
Anatomical Structure Development
Collagen Catabolic Process
Response To Stimulus
Response To External Stimulus
Collagen Metabolic Process
Multicellular Organismal Macromolecule Metabolic Process
Locomotion
Multicellular Organismal Metabolic Process
Cell Differentiation
Wound Healing
Tissue Development
Response To Wounding
Axon Guidance
Response To Growth Factor
Response To Organic Substance
Organ Development
Response To Stress
Cellular Response To Stimulus
Cell Morphogenesis Involved In Differentiation
Movement Of Cell Or Subcellular Component
Neurogenesis
Generation Of Neurons
Chemotaxis
Regulation Of Cell Adhesion
Cell Adhesion
Axon Development
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Axonogenesis
Cell Projection Organization
Cell Morphogenesis
Cardiovascular System Development
Nervous System Development
Neuron Projection Development
Skeletal System Development
Cell Morphogenesis Involved In Neuron Differentiation
Anatomical Structure Formation Involved In Morphogenesis
Neuron Development
Regulation Of Locomotion
Organ Morphogenesis
Cell Communication
Neuron Projection Morphogenesis
Tagcloud
?
2q33
2q34
artificial
bcg
brazilian
exon
il8
il8r
il8ra
il8rb
ity
leishmaniasis
leprosy
linkage
lod
lsh
nramp
pedigrees
proline
pseudogene
q35
q37
segregating
sh3
synteny
tnp1
typed
vil1
visceral
Tagcloud (Difference)
?
2q33
2q34
artificial
bcg
brazilian
exon
il8
il8r
il8ra
il8rb
ity
leishmaniasis
leprosy
linkage
lod
lsh
nramp
pedigrees
proline
pseudogene
q35
q37
segregating
sh3
synteny
tnp1
typed
vil1
visceral
Tagcloud (Intersection)
?