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COL7A1 and BMP1
Number of citations of the paper that reports this interaction (PubMedID
11986329
)
0
Data Source:
HPRD
(in vivo)
COL7A1
BMP1
Description
collagen type VII alpha 1 chain
bone morphogenetic protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Collagen Trimer
Collagen Type VII Trimer
Basement Membrane
Extracellular Space
Endoplasmic Reticulum Lumen
COPII-coated ER To Golgi Transport Vesicle
Extracellular Matrix
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Extracellular Region
Extracellular Space
Golgi Apparatus
Vesicle
Molecular Function
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Extracellular Matrix Structural Constituent Conferring Tensile Strength
Peptidase Inhibitor Activity
Metalloendopeptidase Activity
Serine-type Endopeptidase Activity
Cytokine Activity
Calcium Ion Binding
Protein Binding
Growth Factor Activity
Peptidase Activity
Metallopeptidase Activity
Zinc Ion Binding
Hydrolase Activity
Identical Protein Binding
Metal Ion Binding
Biological Process
Cell Adhesion
Epidermis Development
Endodermal Cell Differentiation
Skeletal System Development
Cartilage Condensation
Ossification
Proteolysis
Signal Transduction
Dorsal/ventral Pattern Formation
Protein Processing
Cell Differentiation
Collagen Fibril Organization
Cartilage Development
Positive Regulation Of Cartilage Development
Pathways
Collagen degradation
Collagen degradation
Fibronectin matrix formation
Collagen biosynthesis and modifying enzymes
Assembly of collagen fibrils and other multimeric structures
COPII-mediated vesicle transport
Integrin cell surface interactions
Anchoring fibril formation
Laminin interactions
Laminin interactions
Cargo concentration in the ER
Collagen chain trimerization
Degradation of the extracellular matrix
Degradation of the extracellular matrix
Collagen biosynthesis and modifying enzymes
Anchoring fibril formation
Crosslinking of collagen fibrils
Drugs
Diseases
Epidermolysis bullosa, dysprophic, including: ; Epidermolysis bullosa dystrophica, AD; Epidermolysis bullosa dystrophica, AR; Epidermolysis bullosa pruriginosa; Epidermolysis bullosa, pretibial
Transient bullous dermolysis of the newborn
GWAS
Age at first sexual intercourse (
27089180
)
Apolipoprotein A1 levels (
32203549
)
Bone fracture in osteoporosis (
28580392
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Crohn's disease (
28067908
)
Inflammatory bowel disease (
28067908
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Ulcerative colitis (
28067908
)
Coronary artery disease (
29212778
)
Hypertriglyceridemia (
23505323
)
Myocardial infarction (
33532862
)
Waist-to-hip ratio adjusted for BMI (
28552196
)
Interacting Genes
15 interacting genes:
BMP1
COL1A1
COL4A1
FBXL2
FN1
HSPA8
LAMA1
LAMA5
LAMB3
LAMC2
MIA3
MMP2
SHKBP1
THBS1
ZC3H7A
14 interacting genes:
ADRA1A
CHRD
COL1A1
COL5A1
COL5A2
COL7A1
GEM
HSPG2
LAMA3
LAMB3
LAMC2
TP53
TWSG1
YLPM1
Entrez ID
1294
649
HPRD ID
00358
00209
Ensembl ID
ENSG00000114270
ENSG00000168487
Uniprot IDs
Q02388
Q59F16
P13497
PDB IDs
3EDG
3EDH
6BSL
6BSM
6BTN
6BTO
6BTP
6BTQ
Enriched GO Terms of Interacting Partners
?
Extracellular Matrix Structural Constituent
Extracellular Matrix
Basement Membrane
Extracellular Region
Regulation Of Cell Migration
Regulation Of Cell Motility
Regulation Of Locomotion
Positive Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Positive Regulation Of Locomotion
Extracellular Space
Extracellular Structure Organization
Extracellular Matrix Organization
Laminin-5 Complex
Regulation Of Cell Adhesion
Endodermal Cell Differentiation
Endoplasmic Reticulum Lumen
Tube Morphogenesis
Morphogenesis Of An Epithelium
Intramembranous Ossification
Retinal Blood Vessel Morphogenesis
Bone Trabecula Formation
Fibrinogen Complex
Tissue Morphogenesis
Blood Coagulation, Fibrin Clot Formation
Retina Vasculature Morphogenesis In Camera-type Eye
Collagen-activated Tyrosine Kinase Receptor Signaling Pathway
Platelet-derived Growth Factor Binding
Branching Involved In Salivary Gland Morphogenesis
Cellular Response To Amino Acid Stimulus
Proteoglycan Binding
Collagen-activated Signaling Pathway
Cell Adhesion
Negative Regulation Of NLRP3 Inflammasome Complex Assembly
Blood Vessel Morphogenesis
Protease Binding
Response To Hyperoxia
Animal Organ Development
Skeletal System Morphogenesis
Angiogenesis
Protein Activation Cascade
Negative Regulation Of Cell Adhesion
Response To Amino Acid
Anatomical Structure Morphogenesis
Ossification
Branching Morphogenesis Of An Epithelial Tube
Receptor Ligand Activity
Developmental Process
Ameboidal-type Cell Migration
Integrin Binding
Basement Membrane
Extracellular Matrix
Extracellular Matrix Structural Constituent
Extracellular Matrix Structural Constituent Conferring Tensile Strength
Fibrillar Collagen Trimer
Extracellular Region
Tissue Development
Collagen Trimer
Collagen Type V Trimer
Negative Regulation Of Endodermal Cell Differentiation
Laminin-5 Complex
Endodermal Cell Differentiation
Collagen Type XI Trimer
Epidermis Development
Hemidesmosome Assembly
Integrin Binding
Skin Development
Hemidesmosome
Collagen Fibril Organization
Regulation Of Developmental Process
Platelet-derived Growth Factor Binding
Collagen Biosynthetic Process
Cell Adhesion
Protease Binding
Response To Xenobiotic Stimulus
Microtubule Plus-end Binding
Endoplasmic Reticulum Lumen
Developmental Process
Microtubule Plus-end
Negative Regulation Of Developmental Process
Animal Organ Development
Anatomical Structure Morphogenesis
System Development
Extracellular Space
Negative Regulation Of Cell Differentiation
Heparin Binding
Regulation Of Cell Differentiation
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Cell-substrate Junction Assembly
Cell Cortex
Structural Molecule Activity
Cell-substrate Junction Organization
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Negative Regulation Of Heart Rate Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure
Regulation Of Cell Population Proliferation
Cellular Response To Vitamin E
Skeletal System Development
Integrin Biosynthetic Process
Collagen Type VII Trimer
Regulation Of Myelination
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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