Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
COL7A1 and FBXL2
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
HPRD
(two hybrid)
COL7A1
FBXL2
Gene Name
collagen, type VII, alpha 1
F-box and leucine-rich repeat protein 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Collagen Type VII Trimer
Basement Membrane
Extracellular Space
Endoplasmic Reticulum Lumen
Extracellular Matrix
Cytoplasm
Membrane
SCF Ubiquitin Ligase Complex
Molecular Function
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Identical Protein Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Calmodulin Binding
Protein Phosphatase Binding
Phosphatidylinositol 3-kinase Regulatory Subunit Binding
Biological Process
Cell Adhesion
Epidermis Development
Negative Regulation Of Endopeptidase Activity
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Collagen Catabolic Process
Endodermal Cell Differentiation
Cellular Protein Modification Process
Proteolysis
Protein Monoubiquitination
Regulation Of Autophagy
Regulation Of Phosphatidylinositol 3-kinase Signaling
Viral Process
Protein Ubiquitination
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways
Collagen formation
Laminin interactions
Collagen degradation
Anchoring fibril formation
Integrin cell surface interactions
Collagen biosynthesis and modifying enzymes
Degradation of the extracellular matrix
Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS
Protein-Protein Interactions
14 interactors:
BMP1
COL1A1
COL4A1
FBXL2
FN1
HSPA8
LAMA1
LAMA5
LAMB3
LAMC2
MMP2
SHKBP1
THBS1
ZC3H7A
7 interactors:
AURKB
CCND2
CDC34
COL7A1
PIK3R2
SKP1
UBE2D3
Entrez ID
1294
25827
HPRD ID
00358
05736
Ensembl ID
ENSG00000114270
ENSG00000153558
Uniprot IDs
Q02388
Q59F16
Q9UKC9
PDB IDs
Enriched GO Terms of Interacting Partners
?
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Extracellular Structure Organization
Tissue Development
Blood Vessel Development
Vasculature Development
Cell-substrate Junction Assembly
Anatomical Structure Morphogenesis
Blood Vessel Morphogenesis
Locomotion
Cardiovascular System Development
Movement Of Cell Or Subcellular Component
Anatomical Structure Formation Involved In Morphogenesis
Angiogenesis
Endodermal Cell Differentiation
Cell Morphogenesis Involved In Differentiation
Anatomical Structure Development
Retinal Blood Vessel Morphogenesis
Cell Junction Assembly
Endoderm Formation
Cellular Response To Amino Acid Stimulus
Developmental Process
Collagen Catabolic Process
Organ Morphogenesis
Intramembranous Ossification
Collagen Metabolic Process
Cell Morphogenesis
Cell Differentiation
Multicellular Organismal Macromolecule Metabolic Process
Skeletal System Morphogenesis
Bone Trabecula Formation
Endoderm Development
Multicellular Organismal Metabolic Process
Multicellular Organismal Development
Cell Adhesion
Retina Vasculature Morphogenesis In Camera-type Eye
Hemidesmosome Assembly
Response To Amino Acid
Bone Trabecula Morphogenesis
Axon Guidance
Formation Of Primary Germ Layer
System Development
Cell Projection Morphogenesis
Cell Part Morphogenesis
Retina Vasculature Development In Camera-type Eye
Morphogenesis Of A Polarized Epithelium
Cellular Response To Acid Chemical
Branching Involved In Salivary Gland Morphogenesis
Gastrulation
Platelet Activation
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Catabolic Process
Protein K48-linked Ubiquitination
Cellular Macromolecule Catabolic Process
Protein Monoubiquitination
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cell Cycle
Protein Ubiquitination
Proteolysis
Response To Growth Factor
Protein Modification By Small Protein Conjugation
Mitotic Cell Cycle Process
Histone H3-S28 Phosphorylation
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Protein Polyubiquitination
Spindle Stabilization
Abscission
Positive Regulation Of Inclusion Body Assembly
Mitotic Spindle Midzone Assembly
Cleavage Furrow Formation
Mitotic Spindle Elongation
Negative Regulation Of CAMP-mediated Signaling
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Cell Cycle Process
Negative Regulation Of Cytokinesis
Protein Localization To Kinetochore
Regulation Of Catalytic Activity
Positive Regulation Of Cell Cycle
Spindle Midzone Assembly
Protein Localization To Chromosome, Centromeric Region
Negative Regulation Of B Cell Apoptotic Process
Attachment Of Spindle Microtubules To Kinetochore
Histone H2A Monoubiquitination
Histone H2A Ubiquitination
Histone-serine Phosphorylation
Regulation Of Metabolic Process
Histone Modification
Regulation Of Inclusion Body Assembly
Regulation Of B Cell Apoptotic Process
Mitotic Spindle Assembly
Histone Monoubiquitination
Cell Division
Tagcloud
?
abca7
adssl1
apoe
bin1
cd2ap
cd33
cognitively
cr1
epha1
hallmark
haplotype
intron
load
map2k4
modifier
ms4a4a
ms4a6e
multifactorial
picalm
plink
pomt2
ppp2r5c
rabgef1
sh3kbp1
snp
snx8
synj1
xpo1
xrn1
Tagcloud (Difference)
?
abca7
adssl1
apoe
bin1
cd2ap
cd33
cognitively
cr1
epha1
hallmark
haplotype
intron
load
map2k4
modifier
ms4a4a
ms4a6e
multifactorial
picalm
plink
pomt2
ppp2r5c
rabgef1
sh3kbp1
snp
snx8
synj1
xpo1
xrn1
Tagcloud (Intersection)
?