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COL7A1 and COL4A1
Number of citations of the paper that reports this interaction (PMID
9169408
)
24
Data Source:
BioGRID
(pull down)
HPRD
(in vitro)
COL7A1
COL4A1
Gene Name
collagen, type VII, alpha 1
collagen, type IV, alpha 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Collagen Type VII Trimer
Basement Membrane
Extracellular Space
Endoplasmic Reticulum Lumen
Extracellular Matrix
Extracellular Region
Collagen Type IV Trimer
Basement Membrane
Endoplasmic Reticulum Lumen
Extracellular Matrix
Molecular Function
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Identical Protein Binding
Extracellular Matrix Structural Constituent
Protein Binding
Extracellular Matrix Constituent Conferring Elasticity
Platelet-derived Growth Factor Binding
Biological Process
Cell Adhesion
Epidermis Development
Negative Regulation Of Endopeptidase Activity
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Collagen Catabolic Process
Endodermal Cell Differentiation
Patterning Of Blood Vessels
Receptor-mediated Endocytosis
Axon Guidance
Brain Development
Neuromuscular Junction Development
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Collagen Catabolic Process
Epithelial Cell Differentiation
Blood Vessel Morphogenesis
Retinal Blood Vessel Morphogenesis
Renal Tubule Morphogenesis
Cellular Response To Amino Acid Stimulus
Basement Membrane Organization
Pathways
Collagen formation
Laminin interactions
Collagen degradation
Anchoring fibril formation
Integrin cell surface interactions
Collagen biosynthesis and modifying enzymes
Degradation of the extracellular matrix
Assembly of collagen fibrils and other multimeric structures
Signaling by PDGF
NCAM1 interactions
Collagen formation
Axon guidance
Collagen degradation
Anchoring fibril formation
Non-integrin membrane-ECM interactions
Degradation of the extracellular matrix
Assembly of collagen fibrils and other multimeric structures
Laminin interactions
ECM proteoglycans
Integrin cell surface interactions
Collagen biosynthesis and modifying enzymes
NCAM signaling for neurite out-growth
Scavenging by Class A Receptors
Drugs
Diseases
GWAS
Arterial stiffness (
20031579
)
Coronary heart disease (
21378990
)
Obesity-related traits (
23251661
)
Protein-Protein Interactions
14 interactors:
BMP1
COL1A1
COL4A1
FBXL2
FN1
HSPA8
LAMA1
LAMA5
LAMB3
LAMC2
MMP2
SHKBP1
THBS1
ZC3H7A
27 interactors:
ACHE
APCS
APP
BMP3
CD93
COL4A2
COL7A1
DCN
DISC1
FBLN2
FN1
HABP2
MAG
MATN2
MMP9
NID1
NID2
OSM
PDGFA
PDGFB
SAA1
SAA2
SAA4
SERPINE2
SMAD1
TGFBI
THBS1
Entrez ID
1294
1282
HPRD ID
00358
00359
Ensembl ID
ENSG00000114270
ENSG00000187498
Uniprot IDs
Q02388
Q59F16
P02462
PDB IDs
1LI1
Enriched GO Terms of Interacting Partners
?
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Extracellular Structure Organization
Tissue Development
Blood Vessel Development
Vasculature Development
Cell-substrate Junction Assembly
Anatomical Structure Morphogenesis
Blood Vessel Morphogenesis
Locomotion
Cardiovascular System Development
Movement Of Cell Or Subcellular Component
Anatomical Structure Formation Involved In Morphogenesis
Angiogenesis
Endodermal Cell Differentiation
Cell Morphogenesis Involved In Differentiation
Anatomical Structure Development
Retinal Blood Vessel Morphogenesis
Cell Junction Assembly
Endoderm Formation
Cellular Response To Amino Acid Stimulus
Developmental Process
Collagen Catabolic Process
Organ Morphogenesis
Intramembranous Ossification
Collagen Metabolic Process
Cell Morphogenesis
Cell Differentiation
Multicellular Organismal Macromolecule Metabolic Process
Skeletal System Morphogenesis
Bone Trabecula Formation
Endoderm Development
Multicellular Organismal Metabolic Process
Multicellular Organismal Development
Cell Adhesion
Retina Vasculature Morphogenesis In Camera-type Eye
Hemidesmosome Assembly
Response To Amino Acid
Bone Trabecula Morphogenesis
Axon Guidance
Formation Of Primary Germ Layer
System Development
Cell Projection Morphogenesis
Cell Part Morphogenesis
Retina Vasculature Development In Camera-type Eye
Morphogenesis Of A Polarized Epithelium
Cellular Response To Acid Chemical
Branching Involved In Salivary Gland Morphogenesis
Gastrulation
Platelet Activation
Extracellular Matrix Organization
Extracellular Structure Organization
Response To Wounding
Wound Healing
Acute-phase Response
Extracellular Matrix Disassembly
Tissue Development
Blood Coagulation
Platelet Degranulation
Hemostasis
Acute Inflammatory Response
Multicellular Organismal Development
System Development
Cell Adhesion
Anatomical Structure Development
Locomotion
Platelet Activation
Response To Stress
Endodermal Cell Differentiation
Regulation Of Body Fluid Levels
Developmental Process
Formation Of Primary Germ Layer
Regulation Of Wound Healing
Inflammatory Response
Endoderm Formation
Anatomical Structure Morphogenesis
Negative Regulation Of Platelet Activation
Negative Regulation Of Wound Healing
Organ Development
Defense Response
Negative Regulation Of Phosphatidylinositol Biosynthetic Process
Gastrulation
Cell Migration
Movement Of Cell Or Subcellular Component
Endoderm Development
Chemotaxis
Positive Regulation Of Metanephric Mesenchymal Cell Migration
Positive Regulation Of Metanephric Mesenchymal Cell Migration By Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Cell Differentiation
Regulation Of Blood Coagulation
Regulation Of Platelet Activation
Cell Motility
Response To Stimulus
Leukocyte Migration
Connective Tissue Development
Blood Vessel Morphogenesis
Negative Regulation Of Phospholipid Biosynthetic Process
Cell Activation
Immune System Process
Regulation Of Protein Metabolic Process
Tagcloud
?
arteriopathy
autosomal
cadasil
cavitary
confirms
eif2b
encountered
entity
excluded
fifty
frequencies
heterogeneous
increasingly
infancy
infarcts
inherited
leukoencephalopathies
leukoencephalopathy
magnetic
matter
onset
oriented
realized
resonance
subcortical
symmetrical
systematic
underestimated
white
Tagcloud (Difference)
?
arteriopathy
autosomal
cadasil
cavitary
confirms
eif2b
encountered
entity
excluded
fifty
frequencies
heterogeneous
increasingly
infancy
infarcts
inherited
leukoencephalopathies
leukoencephalopathy
magnetic
matter
onset
oriented
realized
resonance
subcortical
symmetrical
systematic
underestimated
white
Tagcloud (Intersection)
?