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COL7A1 and LAMB3
Number of citations of the paper that reports this interaction (PMID
9989793
)
13
Data Source:
HPRD
(in vitro, in vivo)
COL7A1
LAMB3
Gene Name
collagen, type VII, alpha 1
laminin, beta 3
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Collagen Type VII Trimer
Basement Membrane
Extracellular Space
Endoplasmic Reticulum Lumen
Extracellular Matrix
Extracellular Region
Laminin-5 Complex
Molecular Function
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Identical Protein Binding
Structural Molecule Activity
Protein Binding
Protein Complex Binding
Biological Process
Cell Adhesion
Epidermis Development
Negative Regulation Of Endopeptidase Activity
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Collagen Catabolic Process
Endodermal Cell Differentiation
Cell Adhesion
Epidermis Development
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Hemidesmosome Assembly
Cell Junction Assembly
Endodermal Cell Differentiation
Brown Fat Cell Differentiation
Pathways
Collagen formation
Laminin interactions
Collagen degradation
Anchoring fibril formation
Integrin cell surface interactions
Collagen biosynthesis and modifying enzymes
Degradation of the extracellular matrix
Assembly of collagen fibrils and other multimeric structures
Cell junction organization
Type I hemidesmosome assembly
Collagen formation
Laminin interactions
Anchoring fibril formation
Non-integrin membrane-ECM interactions
Degradation of the extracellular matrix
Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS
Protein-Protein Interactions
14 interactors:
BMP1
COL1A1
COL4A1
FBXL2
FN1
HSPA8
LAMA1
LAMA5
LAMB3
LAMC2
MMP2
SHKBP1
THBS1
ZC3H7A
5 interactors:
BMP1
COL7A1
LAMA3
LAMC2
THBS1
Entrez ID
1294
3914
HPRD ID
00358
01032
Ensembl ID
ENSG00000114270
ENSG00000196878
Uniprot IDs
Q02388
Q59F16
Q13751
PDB IDs
Enriched GO Terms of Interacting Partners
?
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Extracellular Structure Organization
Tissue Development
Blood Vessel Development
Vasculature Development
Cell-substrate Junction Assembly
Anatomical Structure Morphogenesis
Blood Vessel Morphogenesis
Locomotion
Cardiovascular System Development
Movement Of Cell Or Subcellular Component
Anatomical Structure Formation Involved In Morphogenesis
Angiogenesis
Endodermal Cell Differentiation
Cell Morphogenesis Involved In Differentiation
Anatomical Structure Development
Retinal Blood Vessel Morphogenesis
Cell Junction Assembly
Endoderm Formation
Cellular Response To Amino Acid Stimulus
Developmental Process
Collagen Catabolic Process
Organ Morphogenesis
Intramembranous Ossification
Collagen Metabolic Process
Cell Morphogenesis
Cell Differentiation
Multicellular Organismal Macromolecule Metabolic Process
Skeletal System Morphogenesis
Bone Trabecula Formation
Endoderm Development
Multicellular Organismal Metabolic Process
Multicellular Organismal Development
Cell Adhesion
Retina Vasculature Morphogenesis In Camera-type Eye
Hemidesmosome Assembly
Response To Amino Acid
Bone Trabecula Morphogenesis
Axon Guidance
Formation Of Primary Germ Layer
System Development
Cell Projection Morphogenesis
Cell Part Morphogenesis
Retina Vasculature Development In Camera-type Eye
Morphogenesis Of A Polarized Epithelium
Cellular Response To Acid Chemical
Branching Involved In Salivary Gland Morphogenesis
Gastrulation
Platelet Activation
Extracellular Matrix Organization
Extracellular Structure Organization
Extracellular Matrix Disassembly
Tissue Development
Hemidesmosome Assembly
Epidermis Development
Endodermal Cell Differentiation
Cell Adhesion
Cell-substrate Junction Assembly
Endoderm Formation
Endoderm Development
Negative Regulation Of CGMP-mediated Signaling
Negative Regulation Of Dendritic Cell Antigen Processing And Presentation
Formation Of Primary Germ Layer
Anatomical Structure Development
Anatomical Structure Morphogenesis
Engulfment Of Apoptotic Cell
Negative Regulation Of Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Gastrulation
Cartilage Development
Developmental Process
Cell Junction Assembly
Negative Regulation Of Endothelial Cell Chemotaxis
Negative Regulation Of Nitric Oxide Mediated Signal Transduction
Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport
Anatomical Structure Formation Involved In Morphogenesis
Epithelium Development
Negative Regulation Of Antigen Processing And Presentation
Connective Tissue Development
Regulation Of CGMP-mediated Signaling
Negative Regulation Of Endopeptidase Activity
Skeletal System Morphogenesis
Negative Regulation Of Peptidase Activity
Positive Regulation Of Macrophage Chemotaxis
Negative Regulation Of Plasminogen Activation
Positive Regulation Of Transforming Growth Factor Beta1 Production
Negative Regulation Of Fibrinolysis
Negative Regulation Of Proteolysis
Positive Regulation Of Fibroblast Migration
Protein O-linked Fucosylation
Positive Regulation Of Endothelial Cell Apoptotic Process
Negative Regulation Of Protein Processing
Positive Regulation Of Macrophage Activation
Regulation Of Endopeptidase Activity
Cellular Response To Nitric Oxide
Negative Regulation Of Hydrolase Activity
Chronic Inflammatory Response
Phagocytosis, Engulfment
Regulation Of Fibrinolysis
Regulation Of Protein Processing
Tagcloud
?
besides
built
c13orf18
ccl3
cish
clustering
comprising
cytoreductive
discriminators
et
fosb
gadd45b
granulocytes
hrh4
id2
jak
jak2v617f
klf5
maff
mutational
pim1
signature
socs2
socs3
stat
supervised
tagap
thrombocythemia
trib1
Tagcloud (Difference)
?
besides
built
c13orf18
ccl3
cish
clustering
comprising
cytoreductive
discriminators
et
fosb
gadd45b
granulocytes
hrh4
id2
jak
jak2v617f
klf5
maff
mutational
pim1
signature
socs2
socs3
stat
supervised
tagap
thrombocythemia
trib1
Tagcloud (Intersection)
?