COL7A1 and ZC3H7A

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		COL7A1	ZC3H7A
Description		collagen type VII alpha 1 chain	zinc finger CCCH-type containing 7A
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Collagen Type VII Trimer Basement Membrane Extracellular Space Endoplasmic Reticulum Lumen COPII-coated ER To Golgi Transport Vesicle Extracellular Matrix Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Nucleus
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength Peptidase Inhibitor Activity	RNA Binding Protein Binding Zinc Ion Binding MiRNA Binding Metal Ion Binding
	Biological Process	Cell Adhesion Epidermis Development Endodermal Cell Differentiation	Post-transcriptional Regulation Of Gene Expression MiRNA Processing
Pathways		Collagen degradation Collagen degradation Fibronectin matrix formation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures COPII-mediated vesicle transport Integrin cell surface interactions Anchoring fibril formation Laminin interactions Laminin interactions Cargo concentration in the ER Collagen chain trimerization
Drugs
Diseases		Epidermolysis bullosa, dysprophic, including: ; Epidermolysis bullosa dystrophica, AD; Epidermolysis bullosa dystrophica, AR; Epidermolysis bullosa pruriginosa; Epidermolysis bullosa, pretibial Transient bullous dermolysis of the newborn
GWAS		Age at first sexual intercourse ( 27089180) Apolipoprotein A1 levels ( 32203549) Bone fracture in osteoporosis ( 28580392) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Depression in smokers ( 30219690) Metabolite levels ( 23823483) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) QT interval ( 19305408) Response to selenium supplementation (change in plasma selenium concentration) ( 33382417)
Interacting Genes		15 interacting genes: BMP1 COL1A1 COL4A1 FBXL2 FN1 HSPA8 LAMA1 LAMA5 LAMB3 LAMC2 MIA3 MMP2 SHKBP1 THBS1 ZC3H7A	10 interacting genes: COL7A1 LARP4 MIR16-2 MIR29A MIR7-1 MIR92A2 MORF4L1 PAK1 STK3 WDR83
Entrez ID		1294	29066
HPRD ID		00358	11694
Ensembl ID		ENSG00000114270	ENSG00000122299
Uniprot IDs		Q02388 Q59F16	Q8IWR0
PDB IDs			2D9M
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Structural Constituent Extracellular Matrix Basement Membrane Extracellular Region Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Extracellular Space Extracellular Structure Organization Extracellular Matrix Organization Laminin-5 Complex Regulation Of Cell Adhesion Endodermal Cell Differentiation Endoplasmic Reticulum Lumen Tube Morphogenesis Morphogenesis Of An Epithelium Intramembranous Ossification Retinal Blood Vessel Morphogenesis Bone Trabecula Formation Fibrinogen Complex Tissue Morphogenesis Blood Coagulation, Fibrin Clot Formation Retina Vasculature Morphogenesis In Camera-type Eye Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Platelet-derived Growth Factor Binding Branching Involved In Salivary Gland Morphogenesis Cellular Response To Amino Acid Stimulus Proteoglycan Binding Collagen-activated Signaling Pathway Cell Adhesion Negative Regulation Of NLRP3 Inflammasome Complex Assembly Blood Vessel Morphogenesis Protease Binding Response To Hyperoxia Animal Organ Development Skeletal System Morphogenesis Angiogenesis Protein Activation Cascade Negative Regulation Of Cell Adhesion Response To Amino Acid Anatomical Structure Morphogenesis Ossification Branching Morphogenesis Of An Epithelial Tube Receptor Ligand Activity Developmental Process Ameboidal-type Cell Migration Integrin Binding	RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Organ Growth
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