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COL7A1 and LAMA1
Number of citations of the paper that reports this interaction (PubMedID
9169408
)
0
Data Source:
HPRD
(in vitro)
COL7A1
LAMA1
Description
collagen type VII alpha 1 chain
laminin subunit alpha 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Collagen Trimer
Collagen Type VII Trimer
Basement Membrane
Extracellular Space
Endoplasmic Reticulum Lumen
COPII-coated ER To Golgi Transport Vesicle
Extracellular Matrix
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Extracellular Region
Basement Membrane
Laminin-1 Complex
Laminin-3 Complex
Extracellular Space
Cell-cell Junction
Membrane
Extracellular Matrix
Laminin Complex
Protein Complex Involved In Cell-matrix Adhesion
Molecular Function
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Extracellular Matrix Structural Constituent Conferring Tensile Strength
Peptidase Inhibitor Activity
Signaling Receptor Binding
Extracellular Matrix Structural Constituent
Protein Binding
Glycosphingolipid Binding
Biological Process
Cell Adhesion
Epidermis Development
Endodermal Cell Differentiation
Morphogenesis Of An Epithelial Sheet
Cell Adhesion
Cell Surface Receptor Signaling Pathway
Tissue Development
Regulation Of Cell Adhesion
Regulation Of Cell Migration
Neuron Projection Development
Establishment Of Epithelial Cell Apical/basal Polarity
Positive Regulation Of Cell Adhesion
Regulation Of Embryonic Development
Positive Regulation Of Muscle Cell Differentiation
Retina Development In Camera-type Eye
Epithelial Tube Branching Involved In Lung Morphogenesis
Branching Involved In Salivary Gland Morphogenesis
Retinal Blood Vessel Morphogenesis
Regulation Of Basement Membrane Organization
Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways
Collagen degradation
Collagen degradation
Fibronectin matrix formation
Collagen biosynthesis and modifying enzymes
Assembly of collagen fibrils and other multimeric structures
COPII-mediated vesicle transport
Integrin cell surface interactions
Anchoring fibril formation
Laminin interactions
Laminin interactions
Cargo concentration in the ER
Collagen chain trimerization
Laminin interactions
Laminin interactions
Non-integrin membrane-ECM interactions
ECM proteoglycans
L1CAM interactions
MET activates PTK2 signaling
Attachment of bacteria to epithelial cells
Formation of the dystrophin-glycoprotein complex (DGC)
Formation of the dystrophin-glycoprotein complex (DGC)
Developmental Lineage of Pancreatic Ductal Cells
Drugs
Lanoteplase
Diseases
Epidermolysis bullosa, dysprophic, including: ; Epidermolysis bullosa dystrophica, AD; Epidermolysis bullosa dystrophica, AR; Epidermolysis bullosa pruriginosa; Epidermolysis bullosa, pretibial
Transient bullous dermolysis of the newborn
GWAS
Age at first sexual intercourse (
27089180
)
Apolipoprotein A1 levels (
32203549
)
Bone fracture in osteoporosis (
28580392
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Crohn's disease (
28067908
)
Inflammatory bowel disease (
28067908
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Ulcerative colitis (
28067908
)
Adverse response to drug (
30420678
)
Response to citalopram treatment (
22760553
)
Type 2 diabetes (
22693455
30054458
30297969
32499647
)
Interacting Genes
15 interacting genes:
BMP1
COL1A1
COL4A1
FBXL2
FN1
HSPA8
LAMA1
LAMA5
LAMB3
LAMC2
MIA3
MMP2
SHKBP1
THBS1
ZC3H7A
23 interacting genes:
ACHE
APCS
APP
C3
COL18A1
COL7A1
DAG1
FBLN2
HSPG2
ITGA1
ITGA2
ITGB1
MEP1A
NID1
NT5E
PLAT
PLG
SAA1
SAA2
TGM2
TMPRSS6
UBC
USP7
Entrez ID
1294
284217
HPRD ID
00358
01033
Ensembl ID
ENSG00000114270
ENSG00000101680
Uniprot IDs
Q02388
Q59F16
P25391
PDB IDs
Enriched GO Terms of Interacting Partners
?
Extracellular Matrix Structural Constituent
Extracellular Matrix
Basement Membrane
Extracellular Region
Regulation Of Cell Migration
Regulation Of Cell Motility
Regulation Of Locomotion
Positive Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Positive Regulation Of Locomotion
Extracellular Space
Extracellular Structure Organization
Extracellular Matrix Organization
Laminin-5 Complex
Regulation Of Cell Adhesion
Endodermal Cell Differentiation
Endoplasmic Reticulum Lumen
Tube Morphogenesis
Morphogenesis Of An Epithelium
Intramembranous Ossification
Retinal Blood Vessel Morphogenesis
Bone Trabecula Formation
Fibrinogen Complex
Tissue Morphogenesis
Blood Coagulation, Fibrin Clot Formation
Retina Vasculature Morphogenesis In Camera-type Eye
Collagen-activated Tyrosine Kinase Receptor Signaling Pathway
Platelet-derived Growth Factor Binding
Branching Involved In Salivary Gland Morphogenesis
Cellular Response To Amino Acid Stimulus
Proteoglycan Binding
Collagen-activated Signaling Pathway
Cell Adhesion
Negative Regulation Of NLRP3 Inflammasome Complex Assembly
Blood Vessel Morphogenesis
Protease Binding
Response To Hyperoxia
Animal Organ Development
Skeletal System Morphogenesis
Angiogenesis
Protein Activation Cascade
Negative Regulation Of Cell Adhesion
Response To Amino Acid
Anatomical Structure Morphogenesis
Ossification
Branching Morphogenesis Of An Epithelial Tube
Receptor Ligand Activity
Developmental Process
Ameboidal-type Cell Migration
Integrin Binding
Extracellular Exosome
Laminin Binding
Basement Membrane
Extracellular Matrix
Extracellular Region
Cell Surface
Extracellular Space
Extracellular Matrix Organization
Extracellular Structure Organization
Collagen Binding Involved In Cell-matrix Adhesion
Cell Adhesion
External Side Of Plasma Membrane
Cell-matrix Adhesion
Collagen Binding
Cell-substrate Adhesion
Integrin Alpha1-beta1 Complex
High-density Lipoprotein Particle
Integrin Alpha2-beta1 Complex
Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission
Regulation Of Cell Adhesion
Integrin Complex
Response To Muscle Activity
Calcium Ion Binding
Trans-synaptic Signaling By BDNF
Basement Membrane Organization
Focal Adhesion
Acute-phase Response
Peptidase Activity
Positive Regulation Of Multicellular Organismal Process
Regulation Of Spontaneous Synaptic Transmission
Regulation Of Wound Healing
Modulation Of Chemical Synaptic Transmission
Endoplasmic Reticulum Lumen
Laminin-1 Binding
Positive Regulation Of Cell Adhesion
Integrin Binding
Serine-type Endopeptidase Activity
Inflammatory Response
Regulation Of Apoptotic Cell Clearance
Regulation Of Response To Wounding
Acute Inflammatory Response
Positive Regulation Of Wound Healing
Proteolysis
Branching Involved In Salivary Gland Morphogenesis
Negative Regulation Of Fibrinolysis
Trans-synaptic Signaling, Modulating Synaptic Transmission
Negative Regulation Of Wound Healing
Cell Migration
Regulation Of Multicellular Organismal Process
Regulation Of Cell Communication
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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