Wiki-Pi
About
Search
People
Updates
Search
ADRB2 and EGLN3
Number of citations of the paper that reports this interaction (PubMedID
19584355
)
44
Data Source:
BioGRID
(pull down, pull down)
ADRB2
EGLN3
Description
adrenoceptor beta 2
egl-9 family hypoxia inducible factor 3
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Lysosome
Endosome
Early Endosome
Golgi Apparatus
Plasma Membrane
Cilium
Endosome Membrane
Microtubule Cytoskeleton
Membrane
Apical Plasma Membrane
Clathrin-coated Endocytic Vesicle Membrane
Ciliary Basal Body
Receptor Complex
Intercellular Bridge
Mitotic Spindle
Neuronal Dense Core Vesicle
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
Amyloid-beta Binding
G Protein-coupled Receptor Activity
Adrenergic Receptor Activity
Beta-adrenergic Receptor Activity
Beta2-adrenergic Receptor Activity
Protein Binding
Adenylate Cyclase Binding
Potassium Channel Regulator Activity
Enzyme Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein-containing Complex Binding
Norepinephrine Binding
Iron Ion Binding
Protein Binding
Ferrous Iron Binding
Oxidoreductase Activity
Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen
2-oxoglutarate-dependent Dioxygenase Activity
L-ascorbic Acid Binding
Peptidyl-proline 4-dioxygenase Activity
Metal Ion Binding
Dioxygenase Activity
Hypoxia-inducible Factor-proline Dioxygenase Activity
Biological Process
Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine
Diet Induced Thermogenesis
Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure
Regulation Of Sodium Ion Transport
Transcription By RNA Polymerase II
Receptor-mediated Endocytosis
Smooth Muscle Contraction
Regulation Of Smooth Muscle Contraction
Signal Transduction
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Endosome To Lysosome Transport
Response To Cold
Positive Regulation Of Bone Mineralization
Heat Generation
Negative Regulation Of Multicellular Organism Growth
Positive Regulation Of MAPK Cascade
Bone Resorption
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Smooth Muscle Contraction
Brown Fat Cell Differentiation
Positive Regulation Of Mini Excitatory Postsynaptic Potential
Adrenergic Receptor Signaling Pathway
Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Blood Vessel Diameter Maintenance
AMPA Selective Glutamate Receptor Signaling Pathway
Positive Regulation Of Cold-induced Thermogenesis
Positive Regulation Of CAMP/PKA Signal Transduction
Positive Regulation Of Autophagosome Maturation
Positive Regulation Of Lipophagy
Cellular Response To Amyloid-beta
Response To Psychosocial Stress
Apoptotic Process
DNA Damage Response
Protein Hydroxylation
Regulation Of Neuron Apoptotic Process
Cellular Response To Hypoxia
Pathways
Adrenoceptors
G alpha (s) signalling events
Ub-specific processing proteases
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Drugs
Spermine
Amphetamine
Betaxolol
Bethanidine
Isoetharine
Cabergoline
Metoprolol
Metoprolol
Olanzapine
Atenolol
Norepinephrine
Timolol
Phenylpropanolamine
Dipivefrin
Sotalol
Carteolol
Nortriptyline
Propranolol
Labetalol
Bisoprolol
Epinephrine
Paroxetine
Trimipramine
Cryptenamine
Orciprenaline
Dobutamine
Pseudoephedrine
Alprenolol
Ritodrine
Ritodrine
Terbutaline
Bitolterol
Phenoxybenzamine
Salmeterol
Pindolol
Formoterol
Salbutamol
Ergoloid mesylate
Isoprenaline
Arbutamine
Amiodarone
Carvedilol
Desipramine
Propafenone
Acebutolol
Nadolol
Levobunolol
Metipranolol
Aripiprazole
Arformoterol
Fenoterol
Pirbuterol
Bevantolol
Penbutolol
Ephedra sinica root
Ephedrine
Mephentermine
Procaterol
Clenbuterol
Bambuterol
Oxprenolol
Putrescine
Spermidine
Celiprolol
Nebivolol
Indacaterol
Bedoradrine
NCX 950
Asenapine
Droxidopa
Bufuralol
Protokylol
(S)-carazolol
Bopindolol
Bupranolol
Befunolol
Olodaterol
Vilanterol
Viloxazine
Arotinolol
Doxofylline
Racepinephrine
Dihydroergocornine
DL-Methylephedrine
Etafedrine
Tulobuterol
Levosalbutamol
Dihydroergocristine
Methoxyphenamine
Ascorbic acid
Roxadustat
Daprodustat
Vadadustat
Diseases
Asthma
GWAS
Chronic obstructive pulmonary disease (
30804561
33909500
)
Eosinophil percentage of white cells (
32888494
)
FEV1 (
30804560
)
Lung function (FEV1/FVC) (
30804560
)
Lymphocyte percentage of white cells (
27863252
)
Peak expiratory flow (
30804560
)
Systolic blood pressure (
29615537
)
Alzheimer's disease (late onset) (
30820047
)
Daytime sleep phenotypes (
27126917
)
Hematocrit (
27863252
32888494
)
Hemoglobin (
32888494
)
Iron status biomarkers (ferritin levels) (
33536631
)
Red blood cell count (
32888494
)
Interacting Genes
162 interacting genes:
ABCA7
ADGRG1
ADRB1
ADRB3
AKAP12
AKAP5
ALDOA
ARF4
ARHGAP5
ARHGDIA
ARR3
ARRB1
ARRB2
ARRDC3
ARV1
ATP6V0B
ATP6V0D1
BACE1
BAZ2A
BECN2
BSG
CAV3
CCKBR
CCND2
CD4
CD68
CD81
CD9
CEACAM1
CENPB
CLASP2
CLPTM1L
CNN1
CRYM
CSK
DCAF10
DCLRE1A
DNAJC14
DRD4
EGLN3
EIF2B1
FBXO17
GBP5
GJC2
GMPR2
GNA11
GNA14
GNA15
GNAI1
GNAI2
GNAS
GNAT2
GNB1
GNG2
GNL3L
GOLGB1
GPR37
GPRASP1
GPRC5B
GRB2
GRIA3
GRK1
GRK2
GRK3
GRK4
GRK5
GRK6
GTF2B
HDAC6
HNRNPK
HS2ST1
HTR4
IL1B
IL6R
INSR
KCNE1
KCNJ5
KCNJ6
KCNJ9
KCTD13
KLC1
LRATD2
MAPK8IP2
MBOAT2
MBP
MCAM
MDM2
MFSD12
MFSD2A
MGLL
MITF
MOG
MSR1
NAT14
NCOR2
NEDD4
NHERF1
NHERF2
NIPAL2
NOS1
NPTX1
OBP2A
OPRD1
PLA2G2D
PRDX1
PRKCD
PRNP
PTGDS
PTGER1
PTGES2
RAB14
RAB27A
RAB3A
RACK1
RAN
RAP2C
REL
RGR
RGS10
RGS11
RGS17
RGS2
RGS20
RGS5
RGS8
RGS9
RHOD
RIOX1
RNF41
RTN1
SACS
SENP3
SI
SLC37A1
SLC39A4
SLC52A2
SNCA
SNCG
SPTBN2
SRC
STAT3
STAT4
TCTA
TMCC2
TMEM144
TMEM187
TMEM259
TPTE
TSG101
TSHR
TSPAN7
UCHL1
UST
VAPA
VDAC1
VDAC2
VEGFB
WNK1
YIPF5
YWHAQ
ZNF25
ZNF254
40 interacting genes:
ABI2
ADRB2
ATF4
CDC20
CFTR
CTBP2
DUSP7
EFHC2
EPAS1
EPOR
FAM168B
FOXJ2
GSC2
HIF1A
HIF3A
IK
IKBKG
IKZF3
LDB2
LNX1
MAPK1
MAPK7
MDM2
NCAPH2
NTAQ1
OS9
PKM
PLEKHA2
PRPF19
RBBP8NL
SERTAD1
SIAH2
SUMO1
SUMO2
SUMO3
TP53
TTC23L
WDR83
ZC2HC1A
ZNF655
Entrez ID
154
112399
HPRD ID
00187
06972
Ensembl ID
ENSG00000169252
ENSG00000129521
Uniprot IDs
P07550
X5DQM5
B3KVT0
F8W1G2
Q3T1B0
Q9H6Z9
PDB IDs
1GQ4
2R4R
2R4S
2RH1
3D4S
3KJ6
3NY8
3NY9
3NYA
3P0G
3PDS
3SN6
4GBR
4LDE
4LDL
4LDO
4QKX
5D5A
5D5B
5D6L
5JQH
5X7D
6E67
6KR8
6MXT
6N48
6NI3
6OBA
6PRZ
6PS0
6PS1
6PS2
6PS3
6PS4
6PS5
6PS6
7BZ2
7DHI
7DHR
7XK9
7XKA
8GDZ
8GE1
8GE2
8GE3
8GE4
8GE5
8GE6
8GE7
8GE8
8GE9
8GEA
8GEB
8GEC
8GED
8GEE
8GEF
8GEG
8GEH
8GEI
8GEJ
8GFV
8GFW
8GFX
8GFY
8GFZ
8GG0
8GG1
8GG2
8GG3
8GG4
8GG5
8GG6
8GG7
8GG8
8GG9
8GGA
8GGB
8GGC
8GGE
8GGF
8GGI
8GGJ
8GGK
8GGL
8GGM
8GGN
8GGO
8GGP
8GGQ
8GGR
8GGS
8GGT
8GGU
8GGV
8GGW
8GGX
8GGY
8GGZ
8GH0
8GH1
8JJ8
8JJL
8JJO
8UHB
8UNL
8UNM
8UNN
8UNO
8UNP
8UNQ
8UNR
8UNS
8UNT
8UNU
8UNV
8UNW
8UNX
8UNY
8UNZ
8UO0
8UO1
8UO2
8UO3
8UO4
8W1V
8ZBE
8ZCJ
9CHU
9CHV
9CHX
Enriched GO Terms of Interacting Partners
?
Regulation Of G Protein-coupled Receptor Signaling Pathway
Membrane
G Protein-coupled Receptor Signaling Pathway
Plasma Membrane
GTPase Activity
Receptor Internalization
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Binding
G Protein-coupled Dopamine Receptor Signaling Pathway
Regulation Of Transport
Regulation Of Cell Communication
Regulation Of Signaling
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Regulation Of Signal Transduction
Signal Transduction
G Protein-coupled Receptor Kinase Activity
Regulation Of Biological Quality
Receptor-mediated Endocytosis
Heterotrimeric G-protein Complex
Guanyl Nucleotide Binding
Regulation Of MAPK Cascade
System Process
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Postsynaptic Signal Transduction
G-protein Beta/gamma-subunit Complex Binding
Regulation Of Intracellular Signal Transduction
Beta-adrenergic Receptor Kinase Activity
Negative Regulation Of Signal Transduction
Regulation Of Vesicle-mediated Transport
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Positive Regulation Of Transport
Import Into Cell
Regulation Of Multicellular Organismal Process
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Protein Domain Specific Binding
GTP Binding
Regulation Of Monoatomic Ion Transport
Desensitization Of G Protein-coupled Receptor Signaling Pathway
Beta-2 Adrenergic Receptor Binding
Regulation Of Monoatomic Ion Transmembrane Transport
Negative Regulation Of Transport
Acetylcholine Receptor Signaling Pathway
Endocytosis
Heat Generation
Negative Adaptation Of Signaling Pathway
Regulation Of Endocytosis
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Biological Process Involved In Interaction With Host
Nucleus
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Transcription By RNA Polymerase II
Nuclear Speck
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Regulation Of Protein Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Metabolic Process
Regulation Of RNA Biosynthetic Process
Intracellular Oxygen Homeostasis
Cellular Response To Oxygen Levels
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Response To Hypoxia
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Regulation Of Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Ubiquitin Protein Ligase Binding
Protein Sumoylation
PML Body
Protein Tag Activity
Regulation Of Nucleobase-containing Compound Metabolic Process
Response To Decreased Oxygen Levels
Positive Regulation Of RNA Metabolic Process
Cellular Response To Stress
Response To Oxygen Levels
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Negative Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Cellular Response To Actinomycin D
Transcription Regulator Complex
Cytoplasm
Protein Modification By Small Protein Conjugation
Positive Regulation Of Macromolecule Metabolic Process
Identical Protein Binding
Response To Actinomycin D
Ubiquitin-like Protein Ligase Binding
Regulation Of Apoptotic Signaling Pathway
Enzyme Binding
Embryonic Organ Development
Intracellular Signal Transduction
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Protein Binding
Cellular Response To UV-C
Regulation Of Primary Metabolic Process
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Biosynthetic Process
Protein Modification Process
Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?