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RGS14 and POT1
Number of citations of the paper that reports this interaction (PMID
21044950
)
9
Data Source:
BioGRID
(two hybrid)
RGS14
POT1
Gene Name
regulator of G-protein signaling 14
protection of telomeres 1
Image
Gene Ontology Annotations
Cellular Component
Spindle Pole
Nucleus
Cytoplasm
Centrosome
Spindle
Microtubule
Plasma Membrane
Postsynaptic Density
Nuclear Body
PML Body
Cell Junction
Dendrite
Dendritic Spine
Postsynaptic Membrane
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
G-protein Alpha-subunit Binding
Receptor Signaling Protein Activity
GDP-dissociation Inhibitor Activity
GTPase Activator Activity
Microtubule Binding
Protein Kinase Binding
Receptor Signaling Complex Scaffold Activity
GTPase Activating Protein Binding
Protein Binding
Telomerase Inhibitor Activity
DEAD/H-box RNA Helicase Binding
Single-stranded Telomeric DNA Binding
Biological Process
Nucleocytoplasmic Transport
Response To Oxidative Stress
Spindle Organization
Chromosome Segregation
Mitotic Nuclear Division
Learning
Long-term Memory
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Visual Learning
Zygote Asymmetric Cell Division
Negative Regulation Of Synaptic Plasticity
Intracellular Signal Transduction
Termination Of G-protein Coupled Receptor Signaling Pathway
Negative Regulation Of MAP Kinase Activity
Positive Regulation Of GTPase Activity
Regulation Of DNA-templated Transcription In Response To Stress
Platelet-derived Growth Factor Receptor Signaling Pathway
Positive Regulation Of Neurogenesis
Cell Division
Long-term Synaptic Potentiation
Negative Regulation Of ERK1 And ERK2 Cascade
Telomere Maintenance
Telomere Maintenance Via Telomerase
Telomere Capping
Telomere Formation Via Telomerase
Negative Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Telomere Maintenance Via Telomerase
DNA Duplex Unwinding
Positive Regulation Of Helicase Activity
Positive Regulation Of Telomerase Activity
Negative Regulation Of Telomerase Activity
Positive Regulation Of DNA Strand Elongation
Pathways
Signaling by GPCR
GPCR downstream signaling
G alpha (i) signalling events
Telomere Maintenance
Packaging Of Telomere Ends
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
Cellular Senescence
Meiotic synapsis
Drugs
Diseases
GWAS
Activated partial thromboplastin time (
22703881
)
Chronic kidney disease (
20383146
)
Multiple sclerosis (
21833088
)
Nephrolithiasis (
22396660
)
Renal function-related traits (eGRFcrea) (
22797727
)
Renal function-related traits (sCR) (
22797727
)
Protein-Protein Interactions
15 interactors:
APP
GNA11
GNAI1
GNAI2
GNAI3
GNAO1
NFKB1
POT1
PRKACA
RAP1A
RAP2A
TINF2
TRAF2
WAS
XPO1
166 interactors:
ACD
ACOT7
ACTB
ACTN4
ACY1
AFAP1L2
AHCY
AHNAK
AIPL1
ALDH1A1
ALDH3A1
AMPD2
ANKMY2
ANXA2
ANXA4
APPL2
ARHGDIA
ARID3B
ARRB1
BAG3
BCAS2
BIN2
C15orf57
C2orf74
CALD1
CAMK1D
CCDC9
CCM2
CFL1
CFL2
CKB
CLIC3
CNST
CORO1A
COX6A2
CPNE3
CPPED1
CRK
CRYGS
CSNK2B
CYP4F11
DBN1
DBNL
DCX
DDX19B
DNPH1
DOK2
DPP3
DPYSL3
ECI1
EEF1D
EIF3G
EIF4B
ENO2
ENSA
EPB41L1
EVL
FAM131B
FBP1
FES
GAMT
GAPDH
GAS2L1
GFPT2
GNMT
GPA33
GPR52
GRN
HAAO
HLCS
HMOX1
HNMT
HOXA3
HSP90AB1
HSPA1A
IFRD2
IL1RN
ISYNA1
IVL
KHDRBS1
KIAA1191
KRT18
LAMC3
LASP1
LDHA
LDHB
MADD
MAGEA4
MAP4
MAP4K2
MAP7
MDM2
MICA
MT1X
MVK
MVP
MYO5C
NAP1L1
NCDN
NOL3
NUDC
NUDCD2
NXNL1
PACSIN1
PACSIN2
PAGE2
PAGE5
PAK4
PALM
PCP4
PDE1B
PDLIM2
PEX5
PFKP
PGLS
PGM1
PGM2
PHYHD1
PHYKPL
PIPOX
PRMT7
PROSER2
RBKS
RECQL4
RGS14
RIF1
RPAP1
RPSA
RTN4
SARS
SBDS
SERTAD1
SH3BP1
SNCG
STIP1
STUB1
SULT1B1
SULT1C2
SULT4A1
SYAP1
TAGLN
TBCD
TERF1
TERF2
TINF2
TMSB10
TMSB4Y
TNKS
TOMM34
TPI1
TPP1
TRIM16
TRIP10
TUBB2A
TUBB4B
TWF2
WIBG
WIPI2
XAGE2
YWHAE
YWHAG
ZBED2
ZBTB49
ZFP36L1
ZNF32
ZNF790
Entrez ID
10636
25913
HPRD ID
03944
07572
Ensembl ID
ENSG00000169220
ENSG00000128513
Uniprot IDs
B3KUX0
O43566
A8MTK3
Q5MJ33
Q9NUX5
PDB IDs
2JNU
2OM2
2XNS
3ONW
3QI2
1XJV
3KJO
3KJP
Enriched GO Terms of Interacting Partners
?
Platelet Activation
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Wound Healing
Cell Activation
Response To Wounding
Cell Surface Receptor Signaling Pathway
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Regulation Of Catalytic Activity
Signal Transduction
Negative Regulation Of Adenylate Cyclase Activity
Negative Regulation Of Lyase Activity
Response To Stress
Signaling
Cell Communication
Negative Regulation Of CAMP Biosynthetic Process
Negative Regulation Of CAMP Metabolic Process
Regulation Of Protein Metabolic Process
Negative Regulation Of Nucleotide Metabolic Process
Cellular Response To Stimulus
Negative Regulation Of Catalytic Activity
Negative Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Adenylate Cyclase Activity
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Telomere Assembly
Negative Regulation Of Glial Cell Apoptotic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Protein Metabolic Process
Regulation Of Cyclase Activity
Negative Regulation Of Cellular Metabolic Process
Rap Protein Signal Transduction
Negative Regulation Of Telomere Maintenance
Regulation Of Phosphorus Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Transferase Activity
Positive Regulation Of Catalytic Activity
Positive Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Activation Of Protein Kinase Activity
Regulation Of CAMP Biosynthetic Process
Positive Regulation Of Hydrolase Activity
Regulation Of Protein Phosphorylation
Regulation Of MAPK Cascade
Regulation Of CAMP Metabolic Process
Regulation Of Cellular Process
Positive Regulation Of Cellular Protein Metabolic Process
Protein Localization To Chromosome, Telomeric Region
Regulation Of Telomere Maintenance
Regulation Of Cellular Component Organization
Regulation Of Telomere Maintenance Via Telomerase
Organelle Organization
Negative Regulation Of Telomere Maintenance
Small Molecule Metabolic Process
Cellular Component Assembly
Regulation Of Organelle Organization
Negative Regulation Of Telomere Maintenance Via Telomerase
Cytoskeleton Organization
Organic Acid Metabolic Process
Response To Stimulus
Catabolic Process
Regulation Of Binding
Cellular Process
Carboxylic Acid Metabolic Process
Cofactor Metabolic Process
Protein Localization To Chromosome
Cellular Response To Stimulus
Actin Filament Organization
Protection From Non-homologous End Joining At Telomere
Response To Abiotic Stimulus
Carbohydrate Catabolic Process
Carbohydrate Biosynthetic Process
Protein Localization
Telomere Assembly
Telomere Capping
Positive Regulation Of Organelle Organization
Nervous System Development
Cellular Protein Localization
Response To Stress
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Telomere Maintenance
Cellular Metabolic Process
Pyruvate Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Regulation Of Cytoskeleton Organization
Negative Regulation Of DNA Replication
Response To External Stimulus
Actin Cytoskeleton Organization
Glycolytic Process
Cellular Localization
Regulation Of Protein Metabolic Process
Gluconeogenesis
Sequestering Of Actin Monomers
Regulation Of Neuron Projection Development
Xenobiotic Metabolic Process
Cellular Response To Xenobiotic Stimulus
Developmental Process
Tagcloud
?
0mug
celltiter
chemosensitivity
ddp
downregulate
fluorescein
formerly
gastroesophageal
gc
iodide
isothiocyanate
junction
n87
nci
oncological
oxa
oxaliplatin
performing
pip
platinum
propodium
ptop
telomere
telomeric
tint1
tpp1
trastuzumab
trf2
trf2ip
Tagcloud (Difference)
?
0mug
celltiter
chemosensitivity
ddp
downregulate
fluorescein
formerly
gastroesophageal
gc
iodide
isothiocyanate
junction
n87
nci
oncological
oxa
oxaliplatin
performing
pip
platinum
propodium
ptop
telomere
telomeric
tint1
tpp1
trastuzumab
trf2
trf2ip
Tagcloud (Intersection)
?