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RGS14 and TINF2
Number of citations of the paper that reports this interaction (PMID
21044950
)
9
Data Source:
BioGRID
(two hybrid)
RGS14
TINF2
Gene Name
regulator of G-protein signaling 14
TERF1 (TRF1)-interacting nuclear factor 2
Image
Gene Ontology Annotations
Cellular Component
Spindle Pole
Nucleus
Cytoplasm
Centrosome
Spindle
Microtubule
Plasma Membrane
Postsynaptic Density
Nuclear Body
PML Body
Cell Junction
Dendrite
Dendritic Spine
Postsynaptic Membrane
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleus
Nucleoplasm
Perinucleolar Chromocenter
Nuclear Matrix
Molecular Function
G-protein Alpha-subunit Binding
Receptor Signaling Protein Activity
GDP-dissociation Inhibitor Activity
GTPase Activator Activity
Microtubule Binding
Protein Kinase Binding
Receptor Signaling Complex Scaffold Activity
GTPase Activating Protein Binding
DNA Binding
Protein Binding
Telomeric DNA Binding
Biological Process
Nucleocytoplasmic Transport
Response To Oxidative Stress
Spindle Organization
Chromosome Segregation
Mitotic Nuclear Division
Learning
Long-term Memory
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Visual Learning
Zygote Asymmetric Cell Division
Negative Regulation Of Synaptic Plasticity
Intracellular Signal Transduction
Termination Of G-protein Coupled Receptor Signaling Pathway
Negative Regulation Of MAP Kinase Activity
Positive Regulation Of GTPase Activity
Regulation Of DNA-templated Transcription In Response To Stress
Platelet-derived Growth Factor Receptor Signaling Pathway
Positive Regulation Of Neurogenesis
Cell Division
Long-term Synaptic Potentiation
Negative Regulation Of ERK1 And ERK2 Cascade
Telomere Maintenance
Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Protein ADP-ribosylation
Telomere Assembly
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomerase
Protein Localization To Chromosome
Negative Regulation Of Epithelial Cell Proliferation
Protein Localization To Chromosome, Telomeric Region
Pathways
Signaling by GPCR
GPCR downstream signaling
G alpha (i) signalling events
Telomere Maintenance
Packaging Of Telomere Ends
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
Cellular Senescence
Meiotic synapsis
Drugs
Diseases
GWAS
Activated partial thromboplastin time (
22703881
)
Chronic kidney disease (
20383146
)
Multiple sclerosis (
21833088
)
Nephrolithiasis (
22396660
)
Renal function-related traits (eGRFcrea) (
22797727
)
Renal function-related traits (sCR) (
22797727
)
Protein-Protein Interactions
15 interactors:
APP
GNA11
GNAI1
GNAI2
GNAI3
GNAO1
NFKB1
POT1
PRKACA
RAP1A
RAP2A
TINF2
TRAF2
WAS
XPO1
88 interactors:
ACD
ACOT7
ACTB
ADA
AFAP1L2
AIPL1
AK1
ANKMY2
ANXA4
ANXA5
APOBEC3F
APPL2
ARHGDIA
ARID3B
BAG3
BIN2
CALD1
CCDC43
CCDC9
CKB
CLK3
CPNE3
CRYGS
CTTN
DBN1
DCX
DHFRL1
DPP3
EEF1D
EIF4B
ENO2
FAM131B
FERMT3
FKBP6
GAPDH
GNMT
HNMT
HOXA3
HSP90AB1
IPO5
KCTD17
LASP1
LDHA
LGALSL
LTA4H
MAP2K3
NCDN
NOL3
NUDC
NUDCD2
OR2H1
PAGE2
PAK1IP1
PEX5
PFKP
PGM1
PGM2
PHPT1
PKM
POT1
PPP1R2
PPP6R3
PRKCB
REM2
RGS14
RPSA
SARS
SCRN2
SIAH2
STUB1
SULT1C2
TAGLN
TBL1X
TERF1
TERF2
TOMM34
TPP1
TRIM15
TRIM16
TRIP10
TUBB
TUBB4B
TXNDC17
UCHL1
VIPR1
YWHAG
ZFP36L1
ZNF790
Entrez ID
10636
26277
HPRD ID
03944
16056
Ensembl ID
ENSG00000169220
ENSG00000092330
Uniprot IDs
B3KUX0
O43566
B4DFJ1
Q9BSI4
PDB IDs
2JNU
2OM2
2XNS
3ONW
3QI2
3BQO
3BU8
Enriched GO Terms of Interacting Partners
?
Platelet Activation
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Wound Healing
Cell Activation
Response To Wounding
Cell Surface Receptor Signaling Pathway
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Regulation Of Catalytic Activity
Signal Transduction
Negative Regulation Of Adenylate Cyclase Activity
Negative Regulation Of Lyase Activity
Response To Stress
Signaling
Cell Communication
Negative Regulation Of CAMP Biosynthetic Process
Negative Regulation Of CAMP Metabolic Process
Regulation Of Protein Metabolic Process
Negative Regulation Of Nucleotide Metabolic Process
Cellular Response To Stimulus
Negative Regulation Of Catalytic Activity
Negative Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Adenylate Cyclase Activity
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Telomere Assembly
Negative Regulation Of Glial Cell Apoptotic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Protein Metabolic Process
Regulation Of Cyclase Activity
Negative Regulation Of Cellular Metabolic Process
Rap Protein Signal Transduction
Negative Regulation Of Telomere Maintenance
Regulation Of Phosphorus Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Transferase Activity
Positive Regulation Of Catalytic Activity
Positive Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Activation Of Protein Kinase Activity
Regulation Of CAMP Biosynthetic Process
Positive Regulation Of Hydrolase Activity
Regulation Of Protein Phosphorylation
Regulation Of MAPK Cascade
Regulation Of CAMP Metabolic Process
Regulation Of Cellular Process
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Telomere Maintenance
Telomere Capping
Negative Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomerase Activity
Glycolytic Process
Protection From Non-homologous End Joining At Telomere
Carbohydrate Catabolic Process
Negative Regulation Of DNA Replication
Telomere Assembly
Catabolic Process
Negative Regulation Of DNA Metabolic Process
Protein Localization To Chromosome, Telomeric Region
Negative Regulation Of Catalytic Activity
Positive Regulation Of Telomerase Activity
Pyruvate Metabolic Process
Telomere Maintenance
Telomere Maintenance Via Telomerase
Pathogenesis
Generation Of Precursor Metabolites And Energy
Glucose Metabolic Process
Positive Regulation Of Single-stranded Telomeric DNA Binding
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Negative Regulation Of Chromosome Organization
Small Molecule Metabolic Process
Organic Acid Metabolic Process
Regulation Of DNA Biosynthetic Process
Regulation Of Catalytic Activity
Carboxylic Acid Metabolic Process
Age-dependent Telomere Shortening
Telomeric Loop Formation
Nervous System Development
Regulation Of Signaling
Positive Regulation Of DNA Biosynthetic Process
Glycogen Metabolic Process
RNA-dependent DNA Replication
Nucleoside Metabolic Process
Telomere Maintenance Via Telomere Shortening
Regulation Of Signal Transduction
Hexose Metabolic Process
Cellular Process
Regulation Of DNA Replication
Monocarboxylic Acid Metabolic Process
Cellular Carbohydrate Metabolic Process
Response To Stimulus
Protein Localization To Chromosome
Organelle Organization
Telomere Maintenance Via Telomere Lengthening
Polysaccharide Metabolic Process
Tagcloud
?
acd
add
broader
clustered
clustering
convincingly
correction
cosegregated
ends
families
fisher
germline
inactivating
lod
logarithm
melanoma
nonsense
pot1
predispose
probands
q320x
r364x
shelterin
tailed
terf1
terf2
terf2ip
yates
Tagcloud (Difference)
?
acd
add
broader
clustered
clustering
convincingly
correction
cosegregated
ends
families
fisher
germline
inactivating
lod
logarithm
melanoma
nonsense
pot1
predispose
probands
q320x
r364x
shelterin
tailed
terf1
terf2
terf2ip
yates
Tagcloud (Intersection)
?