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RGS14
Gene Name
regulator of G-protein signaling 14
Image
Gene Ontology Annotations
Cellular Component
Spindle Pole
Nucleus
Cytoplasm
Centrosome
Spindle
Microtubule
Plasma Membrane
Postsynaptic Density
Nuclear Body
PML Body
Cell Junction
Dendrite
Dendritic Spine
Postsynaptic Membrane
Molecular Function
G-protein Alpha-subunit Binding
Receptor Signaling Protein Activity
GDP-dissociation Inhibitor Activity
GTPase Activator Activity
Microtubule Binding
Protein Kinase Binding
Receptor Signaling Complex Scaffold Activity
GTPase Activating Protein Binding
Biological Process
Nucleocytoplasmic Transport
Response To Oxidative Stress
Spindle Organization
Chromosome Segregation
Mitotic Nuclear Division
Learning
Long-term Memory
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Visual Learning
Zygote Asymmetric Cell Division
Negative Regulation Of Synaptic Plasticity
Intracellular Signal Transduction
Termination Of G-protein Coupled Receptor Signaling Pathway
Negative Regulation Of MAP Kinase Activity
Positive Regulation Of GTPase Activity
Regulation Of DNA-templated Transcription In Response To Stress
Platelet-derived Growth Factor Receptor Signaling Pathway
Positive Regulation Of Neurogenesis
Cell Division
Long-term Synaptic Potentiation
Negative Regulation Of ERK1 And ERK2 Cascade
Pathways
Signaling by GPCR
GPCR downstream signaling
G alpha (i) signalling events
Drugs
Diseases
GWAS
Activated partial thromboplastin time (
22703881
)
Chronic kidney disease (
20383146
)
Multiple sclerosis (
21833088
)
Nephrolithiasis (
22396660
)
Renal function-related traits (eGRFcrea) (
22797727
)
Renal function-related traits (sCR) (
22797727
)
Protein-protein Interactions
15 interactors:
APP
GNA11
GNAI1
GNAI2
GNAI3
GNAO1
NFKB1
POT1
PRKACA
RAP1A
RAP2A
TINF2
TRAF2
WAS
XPO1
Entrez ID
10636
HPRD ID
03944
Ensembl ID
ENSG00000169220
Uniprot IDs
B3KUX0
O43566
PDB IDs
2JNU
2OM2
2XNS
3ONW
3QI2
Enriched GO Terms of Interacting Partners
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Platelet Activation
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Wound Healing
Cell Activation
Response To Wounding
Cell Surface Receptor Signaling Pathway
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Regulation Of Catalytic Activity
Signal Transduction
Negative Regulation Of Adenylate Cyclase Activity
Negative Regulation Of Lyase Activity
Response To Stress
Signaling
Cell Communication
Negative Regulation Of CAMP Biosynthetic Process
Negative Regulation Of CAMP Metabolic Process
Regulation Of Protein Metabolic Process
Negative Regulation Of Nucleotide Metabolic Process
Cellular Response To Stimulus
Negative Regulation Of Catalytic Activity
Negative Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Adenylate Cyclase Activity
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Telomere Assembly
Negative Regulation Of Glial Cell Apoptotic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Protein Metabolic Process
Regulation Of Cyclase Activity
Negative Regulation Of Cellular Metabolic Process
Rap Protein Signal Transduction
Negative Regulation Of Telomere Maintenance
Regulation Of Phosphorus Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Transferase Activity
Positive Regulation Of Catalytic Activity
Positive Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Activation Of Protein Kinase Activity
Regulation Of CAMP Biosynthetic Process
Positive Regulation Of Hydrolase Activity
Regulation Of Protein Phosphorylation
Regulation Of MAPK Cascade
Regulation Of CAMP Metabolic Process
Regulation Of Cellular Process
Positive Regulation Of Cellular Protein Metabolic Process
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