IL2RB and PTPN6

  • Number of citations of the paper that reports this interaction (PMID 9520455)
  • 33
  • Data Source:
  • HPRD (in vitro)

IL2RB

PTPN6

Gene Name interleukin 2 receptor, beta protein tyrosine phosphatase, non-receptor type 6
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 27 interactors: CISH EIF3B FYN GNB2L1 GRB2 HGS IL15 IL15RA IL2 IL2RA IL2RG JAK1 JAK3 LCK LYN PIK3R1 PTPN6 RAF1 SHB SHC1 SOCS1 SOCS3 STAT1 STAT3 STAT5A STAT5B SYK 98 interactors: ABL1 ACTN1 ACTN4 BCR BLNK BTLA C6orf25 CAV1 CBL CD22 CD247 CD300LF CD33 CD5 CD72 CD79A CD79B CEACAM1 CLEC4A CSF2RB CTNNB1 CTNND1 CUZD1 CXCR4 DOK1 EGFR EPOR ESR1 FAS FCGR2B FCRL3 FHL3 FLT3 GAB2 GHR GRB2 HOXA10 IFNAR1 IL2RB IL4R IL6ST INSR IRS2 IRS4 JAK1 JAK2 JAK3 KDR KHDRBS1 KIR2DL3 KIR2DL5A KIT KLRAP1 KLRB1 KLRC1 LAIR1 LCK LCP2 LIFR LILRB2 LILRB4 LYN MS4A2 MYH9 NOS1 PAG1 PECAM1 PIK3R1 PILRA PILRB PRKCA PRKCD PTK2B PTPN11 PTPRC ROS1 SHC1 SIGLEC10 SIGLEC11 SIGLEC12 SIRPA SLAMF6 SOS1 SPATA2 SRC SSTR2 STAT5B STAT6 SYK TFG TLR10 TMEM62 TNFRSF1A TRAF6 TREML1 TYK2 VAV1 ZAP70
Entrez ID 3560 5777
HPRD ID 00896 01475
Ensembl ID ENSG00000100385 ENSG00000111679
Uniprot IDs P14784 P29350 Q53XS4
PDB IDs 1ILM 1ILN 2B5I 2ERJ 3QAZ 4GS7 1FPR 1GWZ 1X6C 2B3O 2RMX 2YU7 3PS5 4GRY 4GRZ 4GS0 4HJP 4HJQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
attenuation  autocrine  coculture  coexpression  conundrum  defining  engagement  explanation  favorable  heterotrimer  il15  il15ra  il2rg  infiltrations  jak1  leucocyte  mechanistic  offer  overexpress  paracrine  paradoxical  pras40  rnai  stat2  stroma  subsets  tnbc  unlike 
a2  ag  cd45  chimera  chimeras  chimeric  coupling  diminished  enzymatic  fails  hcp  hemopoietic  initiated  inositol  j45  jurkat  ligation  lymphoid  phosphatase  phospholipase  phosphotyrosine  ptp1c  rescue  shp  shptp  surprisingly  tcr  transduction  unlike 
Tagcloud (Difference) ?
attenuation  autocrine  coculture  coexpression  conundrum  defining  engagement  explanation  favorable  heterotrimer  il15  il15ra  il2rg  infiltrations  jak1  leucocyte  mechanistic  offer  overexpress  paracrine  paradoxical  pras40  rnai  stat2  stroma  subsets  tnbc 
a2  ag  cd45  chimera  chimeras  chimeric  coupling  diminished  enzymatic  fails  hcp  hemopoietic  initiated  inositol  j45  jurkat  ligation  lymphoid  phosphatase  phospholipase  phosphotyrosine  ptp1c  rescue  shp  shptp  surprisingly  tcr  transduction 
Tagcloud (Intersection) ?
unlike