IL2RB and SYK

  • Number of citations of the paper that reports this interaction (PMID 7600304)
  • 19
  • Data Source:
  • HPRD (in vitro)

IL2RB

SYK

Gene Name interleukin 2 receptor, beta spleen tyrosine kinase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 27 interactors: CISH EIF3B FYN GNB2L1 GRB2 HGS IL15 IL15RA IL2 IL2RA IL2RG JAK1 JAK3 LCK LYN PIK3R1 PTPN6 RAF1 SHB SHC1 SOCS1 SOCS3 STAT1 STAT3 STAT5A STAT5B SYK 98 interactors: APP BLNK BTK CALM1 CBL CBLB CD19 CD22 CD3E CD72 CD79A CD79B CRKL CSF2RB CSF3R CTTN DBNL DUSP3 EGFR EPOR ERBB2 ERBB3 ERBB4 FCER1G FCGR1A FCGR2A FCGR3A FCRL3 FGR FYN GAB2 GRB2 HCLS1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC6 HDAC9 HNRNPU IL15RA IL2RB ITGB2 JAK1 LAT LAX1 LCK LCP2 LYN MAP4K1 MAPK3 MAPT MS4A2 NEDD4 NFAM1 PAG1 PIK3AP1 PIK3R1 PIK3R2 PLCG1 PLCG2 POU2AF1 PRKCA PRKD1 PTK2 PTK2B PTPN6 PXN RASA1 RPS10 RPS6KA1 RPS6KB1 RPS6KB2 SELPLG SH2B2 SH2D2A SH3BP2 SHC1 SIT1 SLA SLC4A1 SNCA SRC STAT1 STAT3 STAT5A TERF1 TLR4 TNFRSF1A TRAF6 TUBA1A TUBA4A TYROBP UBASH3B UBB USP25 VAV1 VAV2
Entrez ID 3560 6850
HPRD ID 00896 02514
Ensembl ID ENSG00000100385 ENSG00000165025
Uniprot IDs P14784 A8K4G2 P43405
PDB IDs 1ILM 1ILN 2B5I 2ERJ 3QAZ 4GS7 1A81 1CSY 1CSZ 1XBA 1XBB 1XBC 3BUW 3EMG 3FQE 3FQH 3FQS 3SRV 3TUB 3TUC 3TUD 3VF8 3VF9 4DFL 4DFN 4F4P 4FL1 4FL2 4FL3 4FYN 4FYO 4FZ6 4FZ7 4GFG
Enriched GO Terms of Interacting Partners?
Tagcloud ?
attenuation  autocrine  coculture  coexpression  conundrum  defining  engagement  explanation  favorable  heterotrimer  il15  il15ra  il2rg  infiltrations  jak1  leucocyte  mechanistic  offer  overexpress  paracrine  paradoxical  pras40  rnai  stat2  stroma  subsets  tnbc  unlike 
belongs  bind  binds  blotting  coimmunoprecipitation  contribution  cytokine  domains  epo  epor  erythroid  erythropoietin  far  homology  individually  interaction  jak2  mediate  paper  participated  propose  recombinant  regulates  sh2  src  tandem  tyrosine  tyrosines  ut7 
Tagcloud (Difference) ?
attenuation  autocrine  coculture  coexpression  conundrum  defining  engagement  explanation  favorable  heterotrimer  il15  il15ra  il2rg  infiltrations  jak1  leucocyte  mechanistic  offer  overexpress  paracrine  paradoxical  pras40  rnai  stat2  stroma  subsets  tnbc  unlike 
belongs  bind  binds  blotting  coimmunoprecipitation  contribution  cytokine  domains  epo  epor  erythroid  erythropoietin  far  homology  individually  interaction  jak2  mediate  paper  participated  propose  recombinant  regulates  sh2  src  tandem  tyrosine  tyrosines  ut7 
Tagcloud (Intersection) ?