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TRIM25 and YWHAQ
Number of citations of the paper that reports this interaction (PubMedID
31710640
)
61
Data Source:
BioGRID
(pull down, affinity chromatography technology)
TRIM25
YWHAQ
Description
tripartite motif containing 25
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cytoplasmic Stress Granule
Nuclear Body
Nucleus
Cytoplasm
Cytosol
Focal Adhesion
Membrane
Protein-containing Complex
Synapse
Extracellular Exosome
Molecular Function
Transcription Coactivator Activity
RNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Transferase Activity
Ligase Activity
RIG-I Binding
Cadherin Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Transmembrane Transporter Binding
14-3-3 Protein Binding
Biological Process
Immune System Process
Cytoplasmic Pattern Recognition Receptor Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process
Protein Monoubiquitination
Response To Oxidative Stress
MRNA Transcription
Protein Ubiquitination
Viral Release From Host Cell
Regulation Of Protein Localization
Response To Vitamin D
Cellular Response To Oxidative Stress
ERAD Pathway
RIG-I Signaling Pathway
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Response To Estrogen
Suppression Of Viral Release By Host
Innate Immune Response
Positive Regulation Of DNA-templated Transcription
Regulation Of Viral Entry Into Host Cell
Host-mediated Suppression Of Symbiont Invasion
Defense Response To Virus
Protein K48-linked Ubiquitination
Antiviral Innate Immune Response
Cellular Response To Leukemia Inhibitory Factor
Protein Targeting
Signal Transduction
Small GTPase-mediated Signal Transduction
Intracellular Protein Localization
Substantia Nigra Development
Negative Regulation Of Monoatomic Ion Transmembrane Transport
Negative Regulation Of DNA-templated Transcription
Pathways
ISG15 antiviral mechanism
DDX58/IFIH1-mediated induction of interferon-alpha/beta
Termination of translesion DNA synthesis
Ovarian tumor domain proteases
Interferon gamma signaling
TRAF3-dependent IRF activation pathway
TRAF6 mediated IRF7 activation
TRAF6 mediated NF-kB activation
TRAF6 mediated NF-kB activation
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
Negative regulators of DDX58/IFIH1 signaling
Negative regulators of DDX58/IFIH1 signaling
SARS-CoV-1 activates/modulates innate immune responses
SARS-CoV-2 activates/modulates innate and adaptive immune responses
Evasion by RSV of host interferon responses
RSV-host interactions
PKR-mediated signaling
Modulation of host responses by IFN-stimulated genes
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Regulation of localization of FOXO transcription factors
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
Drugs
Phenethyl Isothiocyanate
Diseases
GWAS
Height (
18391951
)
Lean body mass (
28552196
)
Heart rate variability traits (
22174390
)
Non-response to selective serotonin reuptake inhibitors and depression (
27622933
)
Interacting Genes
77 interacting genes:
AMFR
APC
CASP7
CEBPA
CHKA
CRK
DDX3X
DICER1
EIF4G3
ERCC2
ERG
ESR1
G3BP1
G3BP2
GABARAP
GABARAPL1
GABARAPL2
GATA1
GRIK2
LINC00955
MAP1LC3A
MAP1LC3B
MAP1LC3C
MAP3K13
MEIS2
MIR1-1
MIR155
MIR16-2
MIR19B2
MIR205
MIR206
MIR21
MIR221
MIR25
MIR29A
MIR29B1
MIR34A
MIR363
MIR7-1
MIR92A1
MIR92A2
MIR98
MIRLET7A1
MIRLET7A3
MTA1
OTUB2
PAX2
PIK3R1
PITX2
PLAAT4
PTEN
RBCK1
RIPK3
RNF31
SFN
SLC26A4-AS1
STK11
STK38
SUMO2
TFG
TRAF6
TRIM8
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2J2
UBE2L3
UBE2L6
UBE2N
UBE2V1
USP15
USP39
YWHAQ
ZBTB7A
ZNF24
216 interacting genes:
AARS2
ABL1
ACSL4
ADRB2
AGTR1
AHCY
AKT1S1
ANXA1
ANXA2
AR
ARHGAP10
ARHGEF16
ATP5F1A
BAD
BAX
BCAP31
BCR
BRAF
CABIN1
CAPN3
CBL
CBLL1
CCDC125
CDC25A
CDC25B
CDC25C
CDC5L
CDK11B
CDK14
CDK16
CDKN1A
CDKN1B
CFL1
CHAF1A
CKM
CLTC
COPS4
CSE1L
CSNK1A1
CSNK2A1
CTPS1
DAB2IP
DCPS
DDX1
DDX3X
DHX9
DISC1
DNMT1
DYNC1H1
E2F1
EFNB1
EGFR
EIF4A3
ENO1
EPB41
EPB41L1
EPB41L3
ESR1
ESR2
FASN
FBLN1
FGR
FSCN1
FSHR
FXYD1
GAPDH
GCN1
H2BC8
H4C14
HADHA
HAT1
HAX1
HDAC7
HNRNPC
HNRNPH1
HSPA1A
HSPA8
HSPB1
HUS1
IARS2
ING1
ITCH
ITGB4
KANK1
KCNK15
KCNK3
KCNK9
KIF5B
KLC2
KLC3
KRT1
KRT9
LARP1
LARS2
LDHA
LIMA1
LMNA
LMNB1
LYST
MAGOH
MAP3K3
MAP3K5
MCM3
MDM4
MED1
MEF2D
MPL
MPRIP
MRPS27
MST1R
MTNR1B
MTOR
MYCBP2
NADK
NCL
NCOA1
NCOA3
NDE1
NEDD4L
NFATC1
NFATC2
NFATC4
NFKB1
NIF3L1
NME7
NOLC1
NUMA1
PABPN1
PANK1
PDCD6
PDE3A
PDE3B
PDE4B
PDK1
PDPK1
PDXK
PFKFB2
PFKL
PFN1
PGK1
PHLDB2
PI4KB
PIK3C3
PIK3CB
PKM
PRDX1
PRKCQ
PRKCZ
PRKD1
PRKDC
PRMT5
PSME3
RAI14
RCOR3
REM1
RFC1
RGS3
RGS7
RIPK2
RNASE2
RPL10A
RPL15
RPL19
RPL7
RPLP0
RPLP2
RPS3
RUVBL2
SAMSN1
SH3BP2
SKIC8
SLC27A2
SLC8A1
SLC8A2
SLC8A3
SMAD9
SNRPE
SOCS3
SPR
SPTA1
SPTB
SRSF3
SSBP1
SSX2IP
SUMO2
TCP1
TERT
THRA
TLN1
TNF
TNFAIP3
TPI1
TPR
TRAF6
TRIM25
TRIM28
TRIM42
TSC1
TSC2
TUBA1A
TUBA3C
TUBB
UBQLN4
UCP2
UCP3
ULK4
USP8
VARS1
WDR77
WTAP
WWC2
WWP1
YAP1
YWHAG
ZC3H13
ZHX2
Entrez ID
7706
10971
HPRD ID
02711
00886
Ensembl ID
ENSG00000121060
ENSG00000134308
Uniprot IDs
Q14258
P27348
PDB IDs
4CFG
4LTB
5EYA
5FER
5NT1
5NT2
6FLM
6FLN
2BTP
5IQP
6BCR
6BD2
6BQT
6KZG
6KZH
Enriched GO Terms of Interacting Partners
?
Post-transcriptional Gene Silencing
RISC Complex
MiRNA-mediated Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
Post-transcriptional Regulation Of Gene Expression
Ubiquitin Conjugating Enzyme Activity
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Cellular Response To Nitrogen Starvation
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Negative Regulation Of Signal Transduction
Ubiquitin Protein Ligase Binding
Regulation Of Protein Metabolic Process
Phosphatidylethanolamine Binding
Protein Polyubiquitination
Regulation Of Intracellular Signal Transduction
Regulation Of Signal Transduction
MRNA 3'-UTR Binding
Cellular Response To Stress
Negative Regulation Of Gene Expression
Post-translational Protein Modification
Response To Stress
Regulation Of Primary Metabolic Process
Negative Regulation Of Intracellular Signal Transduction
Positive Regulation Of Macromolecule Metabolic Process
Protein Modification Process
Positive Regulation Of Metabolic Process
Regulation Of Signaling
Regulation Of Cell Communication
Negative Regulation Of Translation
Positive Regulation Of Protein Polyubiquitination
Ubiquitin-protein Transferase Activity
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Protein Ubiquitination
Regulation Of RNA Metabolic Process
Positive Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of Cell Motility
Negative Regulation Of Protein Metabolic Process
Protein Modification By Small Protein Conjugation
Negative Regulation Of Locomotion
Cytosol
Cytoplasm
Regulation Of Signaling
Regulation Of Cell Communication
Intracellular Signal Transduction
Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Regulation Of Multicellular Organismal Process
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Protein Metabolic Process
ATP Binding
Regulation Of Cellular Component Organization
Regulation Of Primary Metabolic Process
Negative Regulation Of Signal Transduction
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Programmed Cell Death
Positive Regulation Of Metabolic Process
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of Metabolic Process
Nucleus
Cadherin Binding
Kinase Activity
Negative Regulation Of Programmed Cell Death
Regulation Of Developmental Process
Nucleobase-containing Compound Metabolic Process
Cellular Response To Stress
Nucleotide Binding
Regulation Of Biological Quality
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Protein Metabolic Process
Cell Cortex
Cellular Response To Oxygen-containing Compound
Response To Stress
Protein-containing Complex
Glucose Catabolic Process
Organelle Organization
Positive Regulation Of Multicellular Organismal Process
Macromolecule Metabolic Process
ADP Metabolic Process
RNA Binding
Cellular Response To Lipid
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Extracellular Exosome
Regulation Of Organelle Organization
Positive Regulation Of Cell Population Proliferation
Glycolytic Process
Cellular Response To Hormone Stimulus
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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