TOP1 |
ERG |
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Gene Name | topoisomerase (DNA) I | v-ets avian erythroblastosis virus E26 oncogene homolog | |
Image | |||
Gene Ontology Annotations | Cellular Component | ||
Molecular Function | |||
Biological Process | |||
Pathways | |||
Drugs | |||
Diseases | |||
GWAS | |||
Protein-Protein Interactions | 55 interactors: APAF1 APP ATM BARD1 BTBD1 BTBD2 BUB3 CASP3 CASP6 CDK8 CKAP5 CSNK2A1 CSNK2A2 DDB2 ELK3 ERCC8 ERG FSHR GEMIN4 GRWD1 IL7R IRF4 IRF8 IRF9 JAK1 JUN KMT2A LIG4 LSM4 MDM2 NCL NCOA6 PDE10A PPP2R2B PRB1 PYGM RBL1 RBL2 RCVRN SF3B1 SFPQ SNRNP70 SNW1 SRSF1 SRSF11 SUMO1 SYMPK TARBP2 TDP1 TOPORS TP53 TRIM32 TUBD1 U2AF2 UBE2I | 61 interactors: ACTB ADAR APP CDC5L CLTC DDX21 DDX23 DKC1 DNAJA1 DNAJA2 DNAJA4 EEF1A2 ELAVL1 ETS2 ETV1 FBL FLI1 HNRNPA1 HNRNPA2B1 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPF HNRNPH1 HNRNPH3 HNRNPU HNRNPUL1 HNRNPUL2 HSPD1 ILF2 ILF3 JUN LANCL1 MATR3 NCL NOLC1 NONO NPM1 NUMA1 PARP1 PCBP1 POLR2A PRKDC PRPF40A PRPF8 PUF60 RCC2 RPLP0 SETDB1 SF3B1 SF3B2 SF3B3 SFPQ SNRNP200 SPI1 SYN1 TOP1 TOP2B USP9X XRN2 | |
Entrez ID | 7150 | 2078 | |
HPRD ID | 00535 | 01298 | |
Ensembl ID | ENSG00000198900 | ENSG00000157554 | |
Uniprot IDs | P11387 | B4DN83 B4DVX5 P11308 | |
PDB IDs | 1A31 1A35 1A36 1EJ9 1K4S 1K4T 1LPQ 1NH3 1R49 1RR8 1RRJ 1SC7 1SEU 1T8I 1TL8 | 1SXE 4IRG 4IRH 4IRI | |
Enriched GO Terms of Interacting Partners? |
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|
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Tagcloud ? | anucleate
catalytically
complements
dispensable
division
evolutionarily
homologs
hypersensitive
inviability
inviable
lethal
mitosis
permissive
pombe
probable
proper
restrictive
schizosaccharomyces
searches
semi
synthetically
thiabendazole
top1p
topoisomerase
trf4
trf4p
trf5
trf5p
ts
|
antitrypsin
chn
chondrosarcoma
desmin
desmoplastic
ectomesenchymoma
etv1
ews
extraskeletal
fkhr
fli1
hhf35
liposarcoma
mic2
myod1
myxoid
p22
pax
pnet
q12
q14
q22
q24
q35
ssx1
stt
stts
syt
tec
witnessed
|
|
Tagcloud (Difference) ? | anucleate
catalytically
complements
dispensable
division
evolutionarily
homologs
hypersensitive
inviability
inviable
lethal
mitosis
permissive
pombe
probable
proper
restrictive
schizosaccharomyces
searches
semi
synthetically
thiabendazole
top1p
topoisomerase
trf4
trf4p
trf5
trf5p
ts
|
antitrypsin
chn
chondrosarcoma
desmin
desmoplastic
ectomesenchymoma
etv1
ews
extraskeletal
fkhr
fli1
hhf35
liposarcoma
mic2
myod1
myxoid
p22
pax
pnet
q12
q14
q22
q24
q35
ssx1
stt
stts
syt
tec
witnessed
|
|
Tagcloud (Intersection) ? |