TOP1 and ERG

  • Number of citations of the paper that reports this interaction (PMID 24591637)
  • 2
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)

TOP1

ERG

Gene Name topoisomerase (DNA) I v-ets avian erythroblastosis virus E26 oncogene homolog
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 55 interactors: APAF1 APP ATM BARD1 BTBD1 BTBD2 BUB3 CASP3 CASP6 CDK8 CKAP5 CSNK2A1 CSNK2A2 DDB2 ELK3 ERCC8 ERG FSHR GEMIN4 GRWD1 IL7R IRF4 IRF8 IRF9 JAK1 JUN KMT2A LIG4 LSM4 MDM2 NCL NCOA6 PDE10A PPP2R2B PRB1 PYGM RBL1 RBL2 RCVRN SF3B1 SFPQ SNRNP70 SNW1 SRSF1 SRSF11 SUMO1 SYMPK TARBP2 TDP1 TOPORS TP53 TRIM32 TUBD1 U2AF2 UBE2I 61 interactors: ACTB ADAR APP CDC5L CLTC DDX21 DDX23 DKC1 DNAJA1 DNAJA2 DNAJA4 EEF1A2 ELAVL1 ETS2 ETV1 FBL FLI1 HNRNPA1 HNRNPA2B1 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPF HNRNPH1 HNRNPH3 HNRNPU HNRNPUL1 HNRNPUL2 HSPD1 ILF2 ILF3 JUN LANCL1 MATR3 NCL NOLC1 NONO NPM1 NUMA1 PARP1 PCBP1 POLR2A PRKDC PRPF40A PRPF8 PUF60 RCC2 RPLP0 SETDB1 SF3B1 SF3B2 SF3B3 SFPQ SNRNP200 SPI1 SYN1 TOP1 TOP2B USP9X XRN2
Entrez ID 7150 2078
HPRD ID 00535 01298
Ensembl ID ENSG00000198900 ENSG00000157554
Uniprot IDs P11387 B4DN83 B4DVX5 P11308
PDB IDs 1A31 1A35 1A36 1EJ9 1K4S 1K4T 1LPQ 1NH3 1R49 1RR8 1RRJ 1SC7 1SEU 1T8I 1TL8 1SXE 4IRG 4IRH 4IRI
Enriched GO Terms of Interacting Partners?
Tagcloud ?
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
antitrypsin  chn  chondrosarcoma  desmin  desmoplastic  ectomesenchymoma  etv1  ews  extraskeletal  fkhr  fli1  hhf35  liposarcoma  mic2  myod1  myxoid  p22  pax  pnet  q12  q14  q22  q24  q35  ssx1  stt  stts  syt  tec  witnessed 
Tagcloud (Difference) ?
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
antitrypsin  chn  chondrosarcoma  desmin  desmoplastic  ectomesenchymoma  etv1  ews  extraskeletal  fkhr  fli1  hhf35  liposarcoma  mic2  myod1  myxoid  p22  pax  pnet  q12  q14  q22  q24  q35  ssx1  stt  stts  syt  tec  witnessed 
Tagcloud (Intersection) ?