TOP1 and APAF1

  • Number of citations of the paper that reports this interaction (PMID 12549820)
  • 1
  • Data Source:
  • BioGRID (unspecified method)

TOP1

APAF1

Gene Name topoisomerase (DNA) I apoptotic peptidase activating factor 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 55 interactors: APAF1 APP ATM BARD1 BTBD1 BTBD2 BUB3 CASP3 CASP6 CDK8 CKAP5 CSNK2A1 CSNK2A2 DDB2 ELK3 ERCC8 ERG FSHR GEMIN4 GRWD1 IL7R IRF4 IRF8 IRF9 JAK1 JUN KMT2A LIG4 LSM4 MDM2 NCL NCOA6 PDE10A PPP2R2B PRB1 PYGM RBL1 RBL2 RCVRN SF3B1 SFPQ SNRNP70 SNW1 SRSF1 SRSF11 SUMO1 SYMPK TARBP2 TDP1 TOPORS TP53 TRIM32 TUBD1 U2AF2 UBE2I 18 interactors: APIP AVEN BCL2L1 BCL2L10 CASP3 CASP4 CASP8 CASP9 CYCS FAS FEM1B HIP1 HSP90AA1 HSPA1A NLRP1 PPP1CA TOP1 TRIAP1
Entrez ID 7150 317
HPRD ID 00535 03755
Ensembl ID ENSG00000198900 ENSG00000120868
Uniprot IDs P11387 O14727
PDB IDs 1A31 1A35 1A36 1EJ9 1K4S 1K4T 1LPQ 1NH3 1R49 1RR8 1RRJ 1SC7 1SEU 1T8I 1TL8 1C15 1CWW 1CY5 1Z6T 2P1H 2YGS 3J2T 3YGS
Enriched GO Terms of Interacting Partners?
Tagcloud ?
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
alleviate  amounts  angiogenesis  anthocyanins  bace2  brings  confirm  downregulate  downregulated  enriched  fruit  great  microarray  microarrays  modulated  mtt  mulberry  mumol  neuroprotection  neuroprotective  neutralize  nutrigenomics  pc12  peptidase  plcb4  preincubated  preincubation  pretreatment  substantially 
Tagcloud (Difference) ?
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
alleviate  amounts  angiogenesis  anthocyanins  bace2  brings  confirm  downregulate  downregulated  enriched  fruit  great  microarray  microarrays  modulated  mtt  mulberry  mumol  neuroprotection  neuroprotective  neutralize  nutrigenomics  pc12  peptidase  plcb4  preincubated  preincubation  pretreatment  substantially 
Tagcloud (Intersection) ?