TOP1 and PDE10A

  • Number of citations of the paper that reports this interaction (PMID 12549820)
  • 1
  • Data Source:
  • BioGRID (unspecified method)

TOP1

PDE10A

Gene Name topoisomerase (DNA) I phosphodiesterase 10A
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Conduct disorder (symptom count) ( 20585324)
  • Thyroid hormone levels ( 23408906)
Protein-Protein Interactions 55 interactors: APAF1 APP ATM BARD1 BTBD1 BTBD2 BUB3 CASP3 CASP6 CDK8 CKAP5 CSNK2A1 CSNK2A2 DDB2 ELK3 ERCC8 ERG FSHR GEMIN4 GRWD1 IL7R IRF4 IRF8 IRF9 JAK1 JUN KMT2A LIG4 LSM4 MDM2 NCL NCOA6 PDE10A PPP2R2B PRB1 PYGM RBL1 RBL2 RCVRN SF3B1 SFPQ SNRNP70 SNW1 SRSF1 SRSF11 SUMO1 SYMPK TARBP2 TDP1 TOPORS TP53 TRIM32 TUBD1 U2AF2 UBE2I 3 interactors: CASP3 TOP1 WDR3
Entrez ID 7150 10846
HPRD ID 00535 17828
Ensembl ID ENSG00000198900 ENSG00000112541
Uniprot IDs P11387 Q9Y233
PDB IDs 1A31 1A35 1A36 1EJ9 1K4S 1K4T 1LPQ 1NH3 1R49 1RR8 1RRJ 1SC7 1SEU 1T8I 1TL8 1LRB 2OUN 2OUP 2OUQ 2OUR 2OUS 2OUU 2OUV 2OUY 2WEY 2Y0J 2ZMF 3SN7 3SNI 3SNL 3UI7 3UUO 4AEL 4AJD 4AJF 4AJG 4AJM 4DDL 4DFF 4FCB 4FCD 4HEU 4HF4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
albeit  baboons  cerebellum  discrepancies  kinetics  ma1  monkey  monkeys  mp  multilinear  negligible  nonhuman  penetrating  periodicals  phosphodiesterase  primates  radiolabeled  radiometabolites  radiotracer  reliably  rhesus  scans  seemingly  suitability  tracer  unlabeled  vt  wiley 
Tagcloud (Difference) ?
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
albeit  baboons  cerebellum  discrepancies  kinetics  ma1  monkey  monkeys  mp  multilinear  negligible  nonhuman  penetrating  periodicals  phosphodiesterase  primates  radiolabeled  radiometabolites  radiotracer  reliably  rhesus  scans  seemingly  suitability  tracer  unlabeled  vt  wiley 
Tagcloud (Intersection) ?