ERG and ILF2

Number of citations of the paper that reports this interaction (PMID 24591637)
2

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ERG	ILF2
Gene Name		v-ets avian erythroblastosis virus E26 oncogene homolog	interleukin enhancer binding factor 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Ribonucleoprotein Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane Ribonucleoprotein Complex
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Signal Transducer Activity Protein Binding Sequence-specific DNA Binding	DNA Binding Double-stranded RNA Binding Protein Binding ATP Binding Transferase Activity Poly(A) RNA Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Protein Phosphorylation Signal Transduction Multicellular Organismal Development Cell Proliferation Cell Differentiation	Transcription, DNA-templated Immune Response Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Metabolite levels (HVA) ( 23319000) Neonatal lupus ( 20662065) White blood cell types ( 21738478)
Protein-Protein Interactions		61 interactors: ACTB ADAR APP CDC5L CLTC DDX21 DDX23 DKC1 DNAJA1 DNAJA2 DNAJA4 EEF1A2 ELAVL1 ETS2 ETV1 FBL FLI1 HNRNPA1 HNRNPA2B1 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPF HNRNPH1 HNRNPH3 HNRNPU HNRNPUL1 HNRNPUL2 HSPD1 ILF2 ILF3 JUN LANCL1 MATR3 NCL NOLC1 NONO NPM1 NUMA1 PARP1 PCBP1 POLR2A PRKDC PRPF40A PRPF8 PUF60 RCC2 RPLP0 SETDB1 SF3B1 SF3B2 SF3B3 SFPQ SNRNP200 SPI1 SYN1 TOP1 TOP2B USP9X XRN2	8 interactors: CCNDBP1 EEF1G EIF2AK2 ERG IL7R PRKDC SGSM2 SREK1
Entrez ID		2078	3608
HPRD ID		01298	04419
Ensembl ID		ENSG00000157554	ENSG00000143621
Uniprot IDs		B4DN83 B4DVX5 P11308	B4DY09 F4ZW62 Q12905 Q53FG3
PDB IDs		1SXE 4IRG 4IRH 4IRI
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Processing MRNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Gene Expression Ribonucleoprotein Complex Biogenesis Metabolic Process Osteoblast Differentiation Positive Regulation Of Gene Expression Posttranscriptional Regulation Of Gene Expression Protein Refolding Positive Regulation Of Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Ribosome Biogenesis Chromosome Organization Ossification Cis Assembly Of Pre-catalytic Spliceosome DNA Metabolic Process Regulation Of MRNA Stability Cell Differentiation Rhythmic Process Developmental Process Regulation Of RNA Stability Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Cellular Process Negative Regulation Of Cellular Metabolic Process MRNA Stabilization Negative Regulation Of Transcription, DNA-templated Circadian Rhythm Ribonucleoprotein Complex Assembly	Immunoglobulin Production Evasion Or Tolerance By Virus Of Host Immune Response Negative Regulation Of Potassium Ion Export Interleukin-7-mediated Signaling Pathway Regulation Of Hematopoietic Stem Cell Differentiation Regulation Of Heart Rate By Hormone Evasion Or Tolerance Of Host Defenses By Virus Late Endosome To Golgi Transport T Cell Differentiation B Cell Activation Regulation Of Translational Initiation By EIF2 Alpha Phosphorylation Pro-B Cell Differentiation Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of T Cell Mediated Cytotoxicity Response To Host Immune Response Lymphocyte Differentiation Immunoglobulin V(D)J Recombination Regulation Of NLRP3 Inflammasome Complex Assembly Peptidyl-amino Acid Modification T Cell Receptor V(D)J Recombination B Cell Lineage Commitment Regulation Of Heart Rate By Chemical Signal Response To Virus Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Peptidyl-histidine Phosphorylation Potassium Ion Export Lymphoid Progenitor Cell Differentiation Regulation Of Translational Initiation In Response To Stress T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Negative Regulation Of Osteoblast Proliferation Ectopic Germ Cell Programmed Cell Death Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Membrane Repolarization Negative Regulation Of T Cell Mediated Immunity Modulation By Virus Of Host Process Leukocyte Cell-cell Adhesion Negative Regulation Of Potassium Ion Transmembrane Transport Potassium Ion Homeostasis Homotypic Cell-cell Adhesion Leukocyte Differentiation Lymph Node Development Positive Regulation Of T Cell Differentiation In Thymus Phosphorelay Signal Transduction System Regulation Of Translation In Response To Stress Response To Interferon-alpha Positive Regulation Of Potassium Ion Transmembrane Transport
Tagcloud ?		antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myod1 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed	abrogates acetylation acetyltransferase cd34 cognate complex contains erythroid erythroleukemic existence globin ilf3 imply intricately k562 link links locus multiprotein obscure origin recruitment repair replication rnai surveyed transcription usage validated
Tagcloud (Difference) ?		antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myod1 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed	abrogates acetylation acetyltransferase cd34 cognate complex contains erythroid erythroleukemic existence globin ilf3 imply intricately k562 link links locus multiprotein obscure origin recruitment repair replication rnai surveyed transcription usage validated
Tagcloud (Intersection) ?