ERG and SYN1

Number of citations of the paper that reports this interaction (PMID 24591637)
2

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ERG	SYN1
Gene Name		v-ets avian erythroblastosis virus E26 oncogene homolog	synapsin I
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Ribonucleoprotein Complex	Golgi Apparatus Cytosol Synaptic Vesicle Cell Junction Dendrite
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Signal Transducer Activity Protein Binding Sequence-specific DNA Binding	Actin Binding Catalytic Activity Transporter Activity Protein Binding ATP Binding Protein Kinase Binding Calcium-dependent Protein Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Protein Phosphorylation Signal Transduction Multicellular Organismal Development Cell Proliferation Cell Differentiation	Synaptic Transmission Neurotransmitter Secretion Metabolic Process Regulation Of Neurotransmitter Secretion Regulation Of Synaptic Vesicle Exocytosis
Pathways			Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Metabolite levels (HVA) ( 23319000) Neonatal lupus ( 20662065) White blood cell types ( 21738478)
Protein-Protein Interactions		61 interactors: ACTB ADAR APP CDC5L CLTC DDX21 DDX23 DKC1 DNAJA1 DNAJA2 DNAJA4 EEF1A2 ELAVL1 ETS2 ETV1 FBL FLI1 HNRNPA1 HNRNPA2B1 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPF HNRNPH1 HNRNPH3 HNRNPU HNRNPUL1 HNRNPUL2 HSPD1 ILF2 ILF3 JUN LANCL1 MATR3 NCL NOLC1 NONO NPM1 NUMA1 PARP1 PCBP1 POLR2A PRKDC PRPF40A PRPF8 PUF60 RCC2 RPLP0 SETDB1 SF3B1 SF3B2 SF3B3 SFPQ SNRNP200 SPI1 SYN1 TOP1 TOP2B USP9X XRN2	30 interactors: AMPH BIN1 BLM CAMK1 CAMK2G CDK5 CRK ERG GRB2 ITSN2 KAT5 MAPK3 NOS1 NOS1AP PAK1 PAK2 PAK3 PFN2 PIK3R1 PLCG1 PRKACA RASA1 S100A1 SH3GL2 SNCA SPTAN1 SRC SYN2 SYN3 VIM
Entrez ID		2078	6853
HPRD ID		01298	02433
Ensembl ID		ENSG00000157554	ENSG00000008056
Uniprot IDs		B4DN83 B4DVX5 P11308	P17600
PDB IDs		1SXE 4IRG 4IRH 4IRI
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Processing MRNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Gene Expression Ribonucleoprotein Complex Biogenesis Metabolic Process Osteoblast Differentiation Positive Regulation Of Gene Expression Posttranscriptional Regulation Of Gene Expression Protein Refolding Positive Regulation Of Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Ribosome Biogenesis Chromosome Organization Ossification Cis Assembly Of Pre-catalytic Spliceosome DNA Metabolic Process Regulation Of MRNA Stability Cell Differentiation Rhythmic Process Developmental Process Regulation Of RNA Stability Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Cellular Process Negative Regulation Of Cellular Metabolic Process MRNA Stabilization Negative Regulation Of Transcription, DNA-templated Circadian Rhythm Ribonucleoprotein Complex Assembly	Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Modification Process Positive Regulation Of Catalytic Activity Endocytosis Positive Regulation Of Metabolic Process Regulation Of Cellular Component Organization Axon Guidance Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Metabolic Process Chemotaxis Regulation Of Kinase Activity Positive Regulation Of Protein Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Axonogenesis Positive Regulation Of Protein Phosphorylation Positive Regulation Of Transport Regulation Of Protein Kinase Activity Positive Regulation Of Transferase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Axon Development Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Neuron Differentiation Locomotion Cell Differentiation Positive Regulation Of Cellular Metabolic Process Signaling Regulation Of Protein Phosphorylation Neuron Projection Morphogenesis Regulation Of Signaling Nervous System Development Neurotrophin TRK Receptor Signaling Pathway Cell Communication Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Neurotrophin Signaling Pathway Regulation Of Cytoskeleton Organization Regulation Of Organelle Organization T Cell Costimulation Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Morphogenesis Involved In Differentiation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Actin Filament-based Process Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Protein Metabolic Process
Tagcloud ?		antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myod1 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed	anthropometry bf bifidobacterium bifidogenic breastfed breastfeeding carbohydrates closer colonized digestive faecal fermentable formula formulas infant inulin microbiota nct00808756 newborns oligofructose orafti prebiotic softer sterile stool stools supplemented synergy1 try
Tagcloud (Difference) ?		antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myod1 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed	anthropometry bf bifidobacterium bifidogenic breastfed breastfeeding carbohydrates closer colonized digestive faecal fermentable formula formulas infant inulin microbiota nct00808756 newborns oligofructose orafti prebiotic softer sterile stool stools supplemented synergy1 try
Tagcloud (Intersection) ?