TOP1 and DDB2

  • Number of citations of the paper that reports this interaction (PMID 12549820)
  • 1
  • Data Source:
  • BioGRID (unspecified method)

TOP1

DDB2

Gene Name topoisomerase (DNA) I damage-specific DNA binding protein 2, 48kDa
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 55 interactors: APAF1 APP ATM BARD1 BTBD1 BTBD2 BUB3 CASP3 CASP6 CDK8 CKAP5 CSNK2A1 CSNK2A2 DDB2 ELK3 ERCC8 ERG FSHR GEMIN4 GRWD1 IL7R IRF4 IRF8 IRF9 JAK1 JUN KMT2A LIG4 LSM4 MDM2 NCL NCOA6 PDE10A PPP2R2B PRB1 PYGM RBL1 RBL2 RCVRN SF3B1 SFPQ SNRNP70 SNW1 SRSF1 SRSF11 SUMO1 SYMPK TARBP2 TDP1 TOPORS TP53 TRIM32 TUBD1 U2AF2 UBE2I 15 interactors: ABL1 CUL4A CUL4B DCLRE1C DDB1 E2F1 HDAC1 HIST2H2AC HIST2H3C NTMT1 TOP1 USP24 USP40 XPA XPC
Entrez ID 7150 1643
HPRD ID 00535 02886
Ensembl ID ENSG00000198900 ENSG00000134574
Uniprot IDs P11387 Q92466
PDB IDs 1A31 1A35 1A36 1EJ9 1K4S 1K4T 1LPQ 1NH3 1R49 1RR8 1RRJ 1SC7 1SEU 1T8I 1TL8 3EI4 3I7L 4E54 4E5Z
Enriched GO Terms of Interacting Partners?
Tagcloud ?
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
adherens  bioassays  bladder  carcinogenic  carcinogens  chemicals  consistently  construct  discriminate  evaluating  foundation  gadd45a  genotoxic  genotoxicity  globaltest  hepg2  implemented  industry  investigating  junction  microarrays  pam  peroxisome  perturbation  pharmaceutical  rrm2b  set  sets  validate 
Tagcloud (Difference) ?
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
adherens  bioassays  bladder  carcinogenic  carcinogens  chemicals  consistently  construct  discriminate  evaluating  foundation  gadd45a  genotoxic  genotoxicity  globaltest  hepg2  implemented  industry  investigating  junction  microarrays  pam  peroxisome  perturbation  pharmaceutical  rrm2b  set  sets  validate 
Tagcloud (Intersection) ?