ERG and LANCL1

Number of citations of the paper that reports this interaction (PMID 24591637)
2

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ERG	LANCL1
Gene Name		v-ets avian erythroblastosis virus E26 oncogene homolog	LanC lantibiotic synthetase component C-like 1 (bacterial)
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Ribonucleoprotein Complex	Nucleus Cytoplasm Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Signal Transducer Activity Protein Binding Sequence-specific DNA Binding	Catalytic Activity G-protein Coupled Receptor Activity Protein Binding Zinc Ion Binding SH3 Domain Binding Glutathione Binding Low-density Lipoprotein Particle Receptor Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Protein Phosphorylation Signal Transduction Multicellular Organismal Development Cell Proliferation Cell Differentiation	G-protein Coupled Receptor Signaling Pathway Metabolic Process
Pathways
Drugs
Diseases
GWAS		Metabolite levels (HVA) ( 23319000) Neonatal lupus ( 20662065) White blood cell types ( 21738478)
Protein-Protein Interactions		61 interactors: ACTB ADAR APP CDC5L CLTC DDX21 DDX23 DKC1 DNAJA1 DNAJA2 DNAJA4 EEF1A2 ELAVL1 ETS2 ETV1 FBL FLI1 HNRNPA1 HNRNPA2B1 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPF HNRNPH1 HNRNPH3 HNRNPU HNRNPUL1 HNRNPUL2 HSPD1 ILF2 ILF3 JUN LANCL1 MATR3 NCL NOLC1 NONO NPM1 NUMA1 PARP1 PCBP1 POLR2A PRKDC PRPF40A PRPF8 PUF60 RCC2 RPLP0 SETDB1 SF3B1 SF3B2 SF3B3 SFPQ SNRNP200 SPI1 SYN1 TOP1 TOP2B USP9X XRN2	3 interactors: ERG STOM VHL
Entrez ID		2078	10314
HPRD ID		01298	16040
Ensembl ID		ENSG00000157554	ENSG00000115365
Uniprot IDs		B4DN83 B4DVX5 P11308	B2R602 O43813 Q53TN2
PDB IDs		1SXE 4IRG 4IRH 4IRI	3E6U 3E73
Enriched GO Terms of Interacting Partners?		MRNA Processing RNA Processing MRNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Gene Expression Ribonucleoprotein Complex Biogenesis Metabolic Process Osteoblast Differentiation Positive Regulation Of Gene Expression Posttranscriptional Regulation Of Gene Expression Protein Refolding Positive Regulation Of Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Ribosome Biogenesis Chromosome Organization Ossification Cis Assembly Of Pre-catalytic Spliceosome DNA Metabolic Process Regulation Of MRNA Stability Cell Differentiation Rhythmic Process Developmental Process Regulation Of RNA Stability Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Cellular Process Negative Regulation Of Cellular Metabolic Process MRNA Stabilization Negative Regulation Of Transcription, DNA-templated Circadian Rhythm Ribonucleoprotein Complex Assembly	Negative Regulation Of Potassium Ion Export Regulation Of Acid-sensing Ion Channel Activity Regulation Of Heart Rate By Hormone Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Ion Transmembrane Transport Regulation Of Heart Rate By Chemical Signal Peptidyl-histidine Phosphorylation Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Potassium Ion Export Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Membrane Repolarization Negative Regulation Of Potassium Ion Transmembrane Transport Potassium Ion Homeostasis Phosphorelay Signal Transduction System Regulation Of Ion Transport Positive Regulation Of Potassium Ion Transmembrane Transport Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Potassium Ion Transport Regulation Of Membrane Repolarization Regulation Of Heart Rate By Cardiac Conduction Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cardiac Muscle Cell Action Potential Involved In Contraction Positive Regulation Of Potassium Ion Transport Regulation Of Sodium Ion Transmembrane Transporter Activity Membrane Depolarization During Action Potential Regulation Of Sodium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential Regulation Of Potassium Ion Transmembrane Transport Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Negative Regulation Of Ion Transmembrane Transport Cardiac Muscle Contraction Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Negative Regulation Of Transmembrane Transport Cellular Response To Drug Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Potassium Ion Transport Heart Contraction Regulation Of Sodium Ion Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Positive Regulation Of Ion Transmembrane Transport Regulation Of Cation Channel Activity Striated Muscle Contraction Regulation Of Striated Muscle Contraction Action Potential Protein Stabilization Negative Regulation Of Ion Transport Cellular Response To Hypoxia
Tagcloud ?		antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myod1 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed	address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward stx4 triggering utilized vamp3 view vps26a
Tagcloud (Difference) ?		antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myod1 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed	address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward stx4 triggering utilized vamp3 view vps26a
Tagcloud (Intersection) ?