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ACTC1 and GAPDH
Number of citations of the paper that reports this interaction (PubMedID
30890647
)
104
Data Source:
BioGRID
(affinity chromatography technology, two hybrid)
ACTC1
GAPDH
Description
actin alpha cardiac muscle 1
glyceraldehyde-3-phosphate dehydrogenase
Image
GO Annotations
Cellular Component
Extracellular Space
Cytoplasm
Cytosol
Cytoskeleton
Actin Filament
Focal Adhesion
Actin Cytoskeleton
Membrane
Sarcomere
Lamellipodium
Filopodium
I Band
Cell Body
Synapse
Extracellular Exosome
Blood Microparticle
Glutamatergic Synapse
Nucleus
Cytoplasm
Lipid Droplet
Cytosol
Cytoskeleton
Plasma Membrane
Microtubule Cytoskeleton
Membrane
Nuclear Membrane
Vesicle
Perinuclear Region Of Cytoplasm
Extracellular Exosome
GAIT Complex
Ribonucleoprotein Complex
Molecular Function
Microfilament Motor Activity
Nucleotide Binding
Protein Binding
ATP Binding
Hydrolase Activity
Myosin Binding
Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity
Protein Binding
Microtubule Binding
Oxidoreductase Activity
Oxidoreductase Activity, Acting On The Aldehyde Or Oxo Group Of Donors, NAD Or NADP As Acceptor
Transferase Activity
Aspartic-type Endopeptidase Inhibitor Activity
Peptidyl-cysteine S-nitrosylase Activity
Identical Protein Binding
NADP Binding
NAD Binding
Disordered Domain Specific Binding
Biological Process
Actin Filament Organization
Response To Xenobiotic Stimulus
Positive Regulation Of Gene Expression
Actin Filament-based Movement
Skeletal Muscle Thin Filament Assembly
Actomyosin Structure Organization
Actin-myosin Filament Sliding
Negative Regulation Of Apoptotic Process
Response To Ethanol
Cardiac Myofibril Assembly
Cardiac Muscle Tissue Morphogenesis
Heart Contraction
Cardiac Muscle Contraction
Cytoplasmic Actin-based Contraction Involved In Cell Motility
Mesenchyme Migration
Microtubule Cytoskeleton Organization
Positive Regulation Of Cytokine Production
Immune System Process
Glucose Metabolic Process
Glycolytic Process
Regulation Of Translation
Apoptotic Process
Negative Regulation Of Endopeptidase Activity
Regulation Of Macroautophagy
Negative Regulation Of Translation
Killing Of Cells Of Another Organism
Positive Regulation Of Type I Interferon Production
Peptidyl-cysteine S-trans-nitrosylation
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Innate Immune Response
Protein Stabilization
Defense Response To Fungus
Neuron Apoptotic Process
Killing By Host Of Symbiont Cells
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Cellular Response To Type II Interferon
Pathways
Striated Muscle Contraction
RHOA GTPase cycle
RHOB GTPase cycle
Regulation of CDH1 Function
Formation of the dystrophin-glycoprotein complex (DGC)
Formation of the dystrophin-glycoprotein complex (DGC)
Glycolysis
Gluconeogenesis
Drugs
NADH
Adenosine-5-Diphosphoribose
Thionicotinamide-Adenine-Dinucleotide
4-(2-Aminoethyl)Benzenesulfonyl Fluoride
Xanthinol
Copper
Artenimol
Diseases
Dilated cardiomyopathy (DCM)
Hypertrophic cardiomyopathy (HCM)
Atrial septal defect
GWAS
Axial length (
24144296
)
Refractive error (
20835239
32231278
)
Blood protein levels (
30072576
)
Interacting Genes
43 interacting genes:
ABLIM3
ABRA
ACTB
ACTN4
ACTR2
AFAP1
ANG
ASH2L
BCL11A
C1QTNF9
CAPN1
CFL1
DMD
DMTN
DYNLL1
EZR
FBXO7
FSCN1
GAPDH
GC
HSPB1
HSPB2
KAT14
KLHL17
KLHL2
KPTN
LASP1
LINC00624
MIB2
MPC1
MYLK
OGT
PLEC
PRKCE
SCIN
SLC4A1
SYNE1
SYNE2
TNNI3K
TWF1
UBC
WAS
WIPF1
92 interacting genes:
ACD
ACTB
ACTC1
ANXA1
ANXA7
APP
AR
ARL15
ATN1
ATXN1
BID
BPGM
BTBD2
CAMK1
CAMK2B
CAMK4
CDKN1A
CDKN2A
CEBPA
CHP1
DUX4
DYNLL1
EGFR
ERBB2
FBXO7
FKBP6
FOXP1
GADD45A
GAS7
GOT2
GRIA2
GRM1
HES1
HNF4G
HSPB2
HTT
ITGB5
KARS1
KAT5
KCNE3
LAMA4
LAMTOR5
LIG4
LINC01554
MAPK1
MTNR1A
MYOC
NFYC
NR1H4
NUFIP2
OGT
OSMR
OSTF1
PAFAH1B3
PCDHA4
PCNA
PDIA2
PGK1
PLD2
POT1
POU2F2
PPM1E
PRDX1
PRKCI
PRPF40A
PSEN1
PSMD11
PTPRF
RAB2A
RBM5
RPA2
RXFP4
S100A6
SERPINB9
SHANK3
SIAH1
SIRT1
SLC2A1
SLC2A4
SMARCA2
SMN1
SUMO4
TERF1
TINF2
TK1
TPPP
TSC2
TXNIP
USP25
WEE2-AS1
YWHAE
YWHAQ
Entrez ID
70
2597
HPRD ID
00015
00713
Ensembl ID
ENSG00000159251
ENSG00000111640
Uniprot IDs
B3KPP5
P68032
P04406
V9HVZ4
PDB IDs
8GSU
8GSW
8GT1
8GT2
8GT3
8GT4
8GT5
8ZB7
8ZI9
8ZJ1
9B3Q
9B3R
1U8F
1ZNQ
3GPD
4WNC
4WNI
6ADE
6IQ6
6M61
6YND
6YNE
6YNF
6YNH
8DNS
8G12
8G13
8G14
8G15
8G16
8G17
8P5F
Enriched GO Terms of Interacting Partners
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Actin Binding
Actin Cytoskeleton
Actin Filament Binding
Cytoskeleton
Actin Filament-based Process
Actin Filament Organization
Cytoplasm
Focal Adhesion
Regulation Of Lamellipodium Assembly
Actin Filament
Supramolecular Fiber Organization
Regulation Of Lamellipodium Organization
Actin Polymerization Or Depolymerization
Actin Cytoskeleton Organization
Myofibril
Cell Projection Assembly
Lamellipodium
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Cytoskeleton Organization
Regulation Of Cell Projection Organization
Cortical Cytoskeleton
Z Disc
Postsynaptic Actin Cytoskeleton
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Regulation Of Cell Projection Assembly
Filopodium
Regulation Of Actin Cytoskeleton Organization
Stress Fiber
Plasma Membrane Bounded Cell Projection Assembly
Negative Regulation Of Actin Filament Depolymerization
Regulation Of Cellular Component Size
Regulation Of Actin Filament-based Process
Cell Projection
Regulation Of Actin Filament Depolymerization
Regulation Of Protein-containing Complex Assembly
Brush Border
Regulation Of Actin Filament Polymerization
Actin Filament-based Movement
Extracellular Exosome
Cytosol
Negative Regulation Of Protein-containing Complex Assembly
Positive Regulation Of Lamellipodium Assembly
Negative Regulation Of Protein-containing Complex Disassembly
Negative Regulation Of Cytoskeleton Organization
Negative Regulation Of Supramolecular Fiber Organization
Regulation Of Cytoskeleton Organization
Establishment Or Maintenance Of Cell Polarity
Regulation Of Actin Filament Organization
Cell Projection Organization
Developmental Process
Cellular Developmental Process
Nucleus
Cell Differentiation
Regulation Of Programmed Cell Death
Regulation Of Phosphorus Metabolic Process
Shelterin Complex
Regulation Of Cellular Component Organization
Negative Regulation Of Metabolic Process
Intracellular Signal Transduction
Positive Regulation Of DNA Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Signal Transduction
Regulation Of Apoptotic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Identical Protein Binding
Nuclear Telomere Cap Complex
Protein-containing Complex
Regulation Of Cellular Localization
Cellular Response To Stress
Regulation Of Cellular Response To Stress
Regulation Of Multicellular Organismal Process
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Protein Localization
Regulation Of DNA Metabolic Process
Telomeric DNA Binding
Telomere Capping
Regulation Of Phosphorylation
Nucleoplasm
Regulation Of Developmental Process
Negative Regulation Of DNA Biosynthetic Process
DNA Biosynthetic Process
Telomere Assembly
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Cell Cycle
Regulation Of Chromosome Organization
Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Phosphate Metabolic Process
Regulation Of Cell Population Proliferation
Negative Regulation Of Biosynthetic Process
Cytosol
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Signaling
Positive Regulation Of Chromosome Organization
Positive Regulation Of Multicellular Organismal Process
Regulation Of Cell Development
Positive Regulation Of Cellular Component Organization
System Development
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Tagcloud (Difference)
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Tagcloud (Intersection)
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