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ACTC1 and CFL1
Number of citations of the paper that reports this interaction (PubMedID
12207032
)
0
Data Source:
HPRD
(in vivo)
ACTC1
CFL1
Description
actin alpha cardiac muscle 1
cofilin 1
Image
GO Annotations
Cellular Component
Extracellular Space
Cytoplasm
Cytosol
Cytoskeleton
Actin Filament
Focal Adhesion
Actin Cytoskeleton
Membrane
Sarcomere
Lamellipodium
Filopodium
I Band
Cell Body
Synapse
Extracellular Exosome
Blood Microparticle
Glutamatergic Synapse
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Actin Cytoskeleton
Membrane
Nuclear Matrix
Lamellipodium
Filopodium
Axon
Growth Cone
Cortical Actin Cytoskeleton
Cell Leading Edge
Lamellipodium Membrane
Mitochondrial Membrane
Vesicle
Ruffle Membrane
Cell Projection
Neuronal Cell Body
Dendritic Spine
Extracellular Exosome
Cofilin-actin Rod
Synaptic Membrane
Glutamatergic Synapse
Postsynaptic Density, Intracellular Component
Molecular Function
Microfilament Motor Activity
Nucleotide Binding
Protein Binding
ATP Binding
Hydrolase Activity
Myosin Binding
Actin Binding
Signaling Receptor Binding
Protein Binding
Protein Phosphatase Binding
Actin Filament Binding
Phosphatidylinositol Bisphosphate Binding
Biological Process
Actin Filament Organization
Response To Xenobiotic Stimulus
Positive Regulation Of Gene Expression
Actin Filament-based Movement
Skeletal Muscle Thin Filament Assembly
Actomyosin Structure Organization
Actin-myosin Filament Sliding
Negative Regulation Of Apoptotic Process
Response To Ethanol
Cardiac Myofibril Assembly
Cardiac Muscle Tissue Morphogenesis
Heart Contraction
Cardiac Muscle Contraction
Cytoplasmic Actin-based Contraction Involved In Cell Motility
Mesenchyme Migration
Mitotic Cytokinesis
Neural Crest Cell Migration
Neural Fold Formation
Protein Import Into Nucleus
Cytoskeleton Organization
Actin Filament Organization
Negative Regulation Of Cell Adhesion
Rho Protein Signal Transduction
Actin Polymerization Or Depolymerization
Response To Virus
Positive Regulation Of Lamellipodium Assembly
Negative Regulation Of Lamellipodium Assembly
Response To Activity
Hippocampus Development
Regulation Of Cell Morphogenesis
Establishment Of Cell Polarity
Cell Projection Organization
Actin Cytoskeleton Organization
Actin Filament Depolymerization
Actin Filament Fragmentation
Positive Regulation Of Cell Growth
Negative Regulation Of Actin Filament Depolymerization
Positive Regulation Of Actin Filament Depolymerization
Positive Regulation Of Synaptic Plasticity
Negative Regulation Of Actin Filament Bundle Assembly
Positive Regulation Of Embryonic Development
Negative Regulation Of Apoptotic Process
Response To Amino Acid
Host-mediated Activation Of Viral Process
Negative Regulation Of Cell Size
Positive Regulation Of Proteolysis
Cell Motility
Modulation Of Chemical Synaptic Transmission
Actin Filament Severing
Establishment Of Spindle Localization
Negative Regulation Of Unidimensional Cell Growth
Positive Regulation Of Focal Adhesion Assembly
Positive Regulation Of Dendritic Spine Development
Regulation Of Dendritic Spine Morphogenesis
Cellular Response To Hydrogen Peroxide
Cellular Response To Interleukin-1
Cellular Response To Interleukin-6
Cellular Response To Tumor Necrosis Factor
Cellular Response To Ether
Cellular Response To Epidermal Growth Factor Stimulus
Modification Of Postsynaptic Actin Cytoskeleton
Negative Regulation Of Dendritic Spine Maintenance
Positive Regulation Of Protein Localization To Cell Leading Edge
Negative Regulation Of Postsynaptic Density Organization
Cellular Response To Insulin-like Growth Factor Stimulus
Negative Regulation Of Cell Motility
Positive Regulation Of Cell Motility
Positive Regulation Of Establishment Of Cell Polarity Regulating Cell Shape
Positive Regulation Of Barbed-end Actin Filament Capping
Pathways
Striated Muscle Contraction
RHOA GTPase cycle
RHOB GTPase cycle
Regulation of CDH1 Function
Formation of the dystrophin-glycoprotein complex (DGC)
Formation of the dystrophin-glycoprotein complex (DGC)
Platelet degranulation
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
Sema3A PAK dependent Axon repulsion
RHO GTPases Activate ROCKs
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Dodecyldimethylamine N-oxide
Copper
Artenimol
Diseases
Dilated cardiomyopathy (DCM)
Hypertrophic cardiomyopathy (HCM)
Atrial septal defect
GWAS
Axial length (
24144296
)
Refractive error (
20835239
32231278
)
Acne (severe) (
24927181
)
Basal cell carcinoma (
31174203
)
Breast cancer (
23535729
)
DNA methylation (variation) (
23725790
)
Keratinocyte cancer (MTAG) (
31174203
)
Neutrophil count (
32888494
)
Platelet count (
32888494
)
Psoriasis (
28537254
)
Waist circumference adjusted for body mass index (
34021172
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
White blood cell count (
32888494
)
Interacting Genes
43 interacting genes:
ABLIM3
ABRA
ACTB
ACTN4
ACTR2
AFAP1
ANG
ASH2L
BCL11A
C1QTNF9
CAPN1
CFL1
DMD
DMTN
DYNLL1
EZR
FBXO7
FSCN1
GAPDH
GC
HSPB1
HSPB2
KAT14
KLHL17
KLHL2
KPTN
LASP1
LINC00624
MIB2
MPC1
MYLK
OGT
PLEC
PRKCE
SCIN
SLC4A1
SYNE1
SYNE2
TNNI3K
TWF1
UBC
WAS
WIPF1
46 interacting genes:
ACTA1
ACTA2
ACTB
ACTC1
ACTG1
APP
ATP1A1
ATXN1
CLCN5
ERBB2
ERBB3
ERBB4
ESR1
FLNA
FNDC3B
HSPH1
LIMK1
LIMK2
MAPK6
MAPK8IP2
MYCBP
MYCBP2
NRK
POT1
PSEN1
PTEN
RAD21
RPS6KA1
SLC2A4
SNRPA
SRC
SSH1
SSH2
SSH3
TAB1
TERF1
TESK1
TESK2
TPI1
TRIM15
UBE2M
UCHL5
WDR1
YWHAG
YWHAQ
YWHAZ
Entrez ID
70
1072
HPRD ID
00015
03261
Ensembl ID
ENSG00000159251
ENSG00000172757
Uniprot IDs
B3KPP5
P68032
P23528
V9HWI5
PDB IDs
8GSU
8GSW
8GT1
8GT2
8GT3
8GT4
8GT5
8ZB7
8ZI9
8ZJ1
9B3Q
9B3R
1Q8G
1Q8X
3J0S
4BEX
5HVK
5L6W
6UBY
6UC0
6UC4
6VAO
Enriched GO Terms of Interacting Partners
?
Actin Binding
Actin Cytoskeleton
Actin Filament Binding
Cytoskeleton
Actin Filament-based Process
Actin Filament Organization
Cytoplasm
Focal Adhesion
Regulation Of Lamellipodium Assembly
Actin Filament
Supramolecular Fiber Organization
Regulation Of Lamellipodium Organization
Actin Polymerization Or Depolymerization
Actin Cytoskeleton Organization
Myofibril
Cell Projection Assembly
Lamellipodium
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Cytoskeleton Organization
Regulation Of Cell Projection Organization
Cortical Cytoskeleton
Z Disc
Postsynaptic Actin Cytoskeleton
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Regulation Of Cell Projection Assembly
Filopodium
Regulation Of Actin Cytoskeleton Organization
Stress Fiber
Plasma Membrane Bounded Cell Projection Assembly
Negative Regulation Of Actin Filament Depolymerization
Regulation Of Cellular Component Size
Regulation Of Actin Filament-based Process
Cell Projection
Regulation Of Actin Filament Depolymerization
Regulation Of Protein-containing Complex Assembly
Brush Border
Regulation Of Actin Filament Polymerization
Actin Filament-based Movement
Extracellular Exosome
Cytosol
Negative Regulation Of Protein-containing Complex Assembly
Positive Regulation Of Lamellipodium Assembly
Negative Regulation Of Protein-containing Complex Disassembly
Negative Regulation Of Cytoskeleton Organization
Negative Regulation Of Supramolecular Fiber Organization
Regulation Of Cytoskeleton Organization
Establishment Or Maintenance Of Cell Polarity
Regulation Of Actin Filament Organization
Cell Projection Organization
Actin Cytoskeleton Organization
Actin Filament-based Process
ATP Binding
Regulation Of Organelle Organization
Regulation Of Cellular Component Organization
Nucleotide Binding
Focal Adhesion
Protein Modification Process
Cytoplasm
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Protein Localization
Regulation Of Supramolecular Fiber Organization
Protein Kinase Activity
Regulation Of Multicellular Organismal Process
Actin Filament
Cytoskeleton
Positive Regulation Of Multicellular Organismal Process
Mesenchyme Migration
Regulation Of Protein Localization To Nucleus
Cytoskeleton Organization
Regulation Of Membrane Potential
Developmental Process
Protein Phosphorylation
Cell Junction Organization
ERBB2 Signaling Pathway
Positive Regulation Of Metabolic Process
Regulation Of Actin Filament Organization
Kinase Activity
Protein-containing Complex
Lamellipodium
Regulation Of Actin Filament-based Process
Anatomical Structure Morphogenesis
Phosphorylation
Organelle Organization
Positive Regulation Of Cell Activation
Protein Tyrosine Kinase Activity
Regulation Of Macromolecule Biosynthetic Process
Phosphatase Activity
Positive Regulation Of Signaling
Negative Regulation Of Apoptotic Process
Intracellular Signal Transduction
Negative Regulation Of Cellular Component Organization
Positive Regulation Of Signal Transduction
Protein Localization To Cell Junction
Positive Regulation Of MAPK Cascade
Negative Regulation Of Programmed Cell Death
Regulation Of Actin Cytoskeleton Organization
Protein Serine/threonine Phosphatase Activity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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