SMN1 and A2M

  • Number of citations of the paper that reports this interaction (PMID 21900206)
  • 27
  • Data Source:
  • BioGRID (two hybrid)

SMN1

A2M

Gene Name survival of motor neuron 1, telomeric alpha-2-macroglobulin
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 136 interactors: A1BG A2M ACTB ACTL6B ADAMTS10 AGAP1 APLP1 ARFGAP1 ATP5B ATP6V1A BAG6 BCL2 C19orf60 CARHSP1 CCDC90B CENPB COIL COL4A2 COL4A5 COPS6 CPNE6 CRIP2 CSAD DDAH2 DDX20 DHX9 DMPK DOCK7 DUS2 DYNC1I1 EEF1A1 EIF3G EXT2 EZH2 FAM20C FBL FGB FLAD1 FUBP1 GAPDH GAR1 GDF9 GEMIN2 GEMIN5 GEMIN7 HADHB HIST3H3 HMGXB3 HNRNPR HNRNPU HNRNPUL1 IGHM ILF3 IMMT INPP5K JADE1 KDM1A KIF5A KLHL5 KMT2B KPNB1 LENG8 LRIF1 LSM1 LSM10 LSM11 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MAST2 MED31 MKI67 MPP1 MRPL37 MSH2 NGFR NKIRAS2 NMT2 OSTF1 PDE4DIP PKM PLXNA3 POLR2A POP7 PSME1 QARS RBBP4 RBBP6 RBFOX2 RBM48 RN7SL1 RNU1-1 RNU2-1 RPL13 RPS2 RXRA SDF4 SEMA5B SETDB1 SMC5 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNUPN SP110 STRAP STXBP2 STXBP3 SULT1A3 SUMO3 SYNCRIP TAF1C TIAL1 TLE1 TMSB4X TP53 TRMT2A TUBA1A TUBB3 UCHL1 UNC119 USP4 WDR18 WDR73 WDYHV1 WIZ ZBTB16 ZNF431 ZRANB2 ZXDC 93 interactors: ACTB ADAM19 ADAMTS1 AMBP ANXA6 ANXA7 AP1M2 APOE APP ATF7IP ATP1A1 B2M C11orf58 CDC37 CDC42 CDK2AP2 CDKN1A CELA1 CPB2 CTSB CTSE CYP2C18 CYP2C8 DNAJB1 ECSIT EGLN2 ELAVL3 ENO2 EVI5L EXOSC1 FARSA FBXL12 FBXW4 FIS1 GCDH GEM GRB2 H2AFX HMOX2 HSPA5 IFIT3 IFIT5 IGSF8 IL10 IL1B IL4 KLK13 KLK2 KLK3 LCAT LEP LONP1 LRP1 LYZ MAST1 MGEA5 MLST8 MMP2 MYOC NCDN NGF NOS3 NUDT21 PAEP PAXIP1 PDGFA PDGFB PRAM1 PRDX2 RAB3A RAD23A RAP1B RETN RHEB RNF32 RPP14 SEPT8 SHBG SMN1 STAMBPL1 SWSAP1 TGFBI TGIF1 TGM2 TK1 TNFRSF14 TRAPPC5 TSC22D1 TTR TUBA1B TYRO3 UFD1L UMPS
Entrez ID 6606 2
HPRD ID 02646 00072
Ensembl ID ENSG00000172062 ENSG00000175899
Uniprot IDs B4DP61 Q16637 P01023
PDB IDs 1G5V 1MHN 2LEH 3S6N 4A4E 4A4G 4GLI 1BV8 2P9R 4ACQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
atrophy  centromeric  compensate  copies  copy  degeneration  deletions  detectable  display  donor  easily  exon  fails  fatal  harbor  hindering  homozygous  infant  intragenic  italian  modifier  muscular  null  predictable  sma  smn2  splice  unusually  weakness 
a1at  aptt  clauss  coaliza  eclt  euglobulin  fbg  fibrinolysis  fibrinolytic  foetopathy  foetus  gdm  haemostasis  hemocoagulation  interleukins  kabi  les  leucocytic  macroglobulin  microturbidimetry  orm  orosomucoid  prea  prealbumin  proteinases  thrombocytes  thrombophilia  varicosities  wither 
Tagcloud (Difference) ?
atrophy  centromeric  compensate  copies  copy  degeneration  deletions  detectable  display  donor  easily  exon  fails  fatal  harbor  hindering  homozygous  infant  intragenic  italian  modifier  muscular  null  predictable  sma  smn2  splice  unusually  weakness 
a1at  aptt  clauss  coaliza  eclt  euglobulin  fbg  fibrinolysis  fibrinolytic  foetopathy  foetus  gdm  haemostasis  hemocoagulation  interleukins  kabi  les  leucocytic  macroglobulin  microturbidimetry  orm  orosomucoid  prea  prealbumin  proteinases  thrombocytes  thrombophilia  varicosities  wither 
Tagcloud (Intersection) ?