SMN1 and EZH2

  • Number of citations of the paper that reports this interaction (PMID 21900206)
  • 27
  • Data Source:
  • BioGRID (two hybrid)

SMN1

EZH2

Gene Name survival of motor neuron 1, telomeric enhancer of zeste 2 polycomb repressive complex 2 subunit
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 136 interactors: A1BG A2M ACTB ACTL6B ADAMTS10 AGAP1 APLP1 ARFGAP1 ATP5B ATP6V1A BAG6 BCL2 C19orf60 CARHSP1 CCDC90B CENPB COIL COL4A2 COL4A5 COPS6 CPNE6 CRIP2 CSAD DDAH2 DDX20 DHX9 DMPK DOCK7 DUS2 DYNC1I1 EEF1A1 EIF3G EXT2 EZH2 FAM20C FBL FGB FLAD1 FUBP1 GAPDH GAR1 GDF9 GEMIN2 GEMIN5 GEMIN7 HADHB HIST3H3 HMGXB3 HNRNPR HNRNPU HNRNPUL1 IGHM ILF3 IMMT INPP5K JADE1 KDM1A KIF5A KLHL5 KMT2B KPNB1 LENG8 LRIF1 LSM1 LSM10 LSM11 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MAST2 MED31 MKI67 MPP1 MRPL37 MSH2 NGFR NKIRAS2 NMT2 OSTF1 PDE4DIP PKM PLXNA3 POLR2A POP7 PSME1 QARS RBBP4 RBBP6 RBFOX2 RBM48 RN7SL1 RNU1-1 RNU2-1 RPL13 RPS2 RXRA SDF4 SEMA5B SETDB1 SMC5 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNUPN SP110 STRAP STXBP2 STXBP3 SULT1A3 SUMO3 SYNCRIP TAF1C TIAL1 TLE1 TMSB4X TP53 TRMT2A TUBA1A TUBB3 UCHL1 UNC119 USP4 WDR18 WDR73 WDYHV1 WIZ ZBTB16 ZNF431 ZRANB2 ZXDC 64 interactors: AKT1 ATP1A1 ATP1B1 ATRX BRCA1 C7orf25 CCDC85B CDK1 CDK2 CDK6 CDKN2B-AS1 CEP63 DNAJB11 DNMT1 DNMT3A DNMT3B E2F6 EED EHMT1 EPC2 GADD45G GTF3C1 HDAC1 HIST1H1A HIST1H3A HIST3H3 HOTAIR JAK2 KDM1A KLHDC2 MAP3K7 MAPK8IP2 MAPKAPK3 MED1 NINL PFDN1 PHB2 PHF1 PIN4 PJA1 POLA2 PRMT5 PSMB6 RASA1 RBBP4 RBL2 RELA RELB RPN2 RPS6KA5 SMN1 SMS SMYD3 SUV39H1 SUZ12 TAF1D TK1 TNFSF11 USP7 VAV1 WDR61 WSB2 ZAK ZMYND11
Entrez ID 6606 2146
HPRD ID 02646 03342
Ensembl ID ENSG00000172062 ENSG00000106462
Uniprot IDs B4DP61 Q16637 Q15910 S4S3R8
PDB IDs 1G5V 1MHN 2LEH 3S6N 4A4E 4A4G 4GLI 2C6V 4MI0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
atrophy  centromeric  compensate  copies  copy  degeneration  deletions  detectable  display  donor  easily  exon  fails  fatal  harbor  hindering  homozygous  infant  intragenic  italian  modifier  muscular  null  predictable  sma  smn2  splice  unusually  weakness 
70z  bait  cdnas  coexpressed  coimmunoprecipitated  compositions  confirming  developmentally  drosophila  ectoderm  eed  esc  fragment  gal4  homolog  hybrid  hypomorphic  lethal  mammalian  polycomb  repeats  represses  repressor  silenced  t1031a  t1040c  wd40  yeast  zeste 
Tagcloud (Difference) ?
atrophy  centromeric  compensate  copies  copy  degeneration  deletions  detectable  display  donor  easily  exon  fails  fatal  harbor  hindering  homozygous  infant  intragenic  italian  modifier  muscular  null  predictable  sma  smn2  splice  unusually  weakness 
70z  bait  cdnas  coexpressed  coimmunoprecipitated  compositions  confirming  developmentally  drosophila  ectoderm  eed  esc  fragment  gal4  homolog  hybrid  hypomorphic  lethal  mammalian  polycomb  repeats  represses  repressor  silenced  t1031a  t1040c  wd40  yeast  zeste 
Tagcloud (Intersection) ?