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SMN1 and ZXDC
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
SMN1
ZXDC
Gene Name
survival of motor neuron 1, telomeric
ZXD family zinc finger C
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Spliceosomal Complex
Cytoplasm
Cytosol
Cajal Body
Z Disc
SMN Complex
SMN-Sm Protein Complex
Gemini Of Coiled Bodies
Cellular_component
Nucleus
Molecular Function
RNA Binding
Protein Binding
Identical Protein Binding
Nucleic Acid Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
LRR Domain Binding
Metal Ion Binding
C2H2 Zinc Finger Domain Binding
Biological Process
Spliceosomal Complex Assembly
Spliceosomal SnRNP Assembly
Nervous System Development
Gene Expression
NcRNA Metabolic Process
Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Pathways
snRNP Assembly
Metabolism of non-coding RNA
Drugs
Diseases
GWAS
Protein-Protein Interactions
136 interactors:
A1BG
A2M
ACTB
ACTL6B
ADAMTS10
AGAP1
APLP1
ARFGAP1
ATP5B
ATP6V1A
BAG6
BCL2
C19orf60
CARHSP1
CCDC90B
CENPB
COIL
COL4A2
COL4A5
COPS6
CPNE6
CRIP2
CSAD
DDAH2
DDX20
DHX9
DMPK
DOCK7
DUS2
DYNC1I1
EEF1A1
EIF3G
EXT2
EZH2
FAM20C
FBL
FGB
FLAD1
FUBP1
GAPDH
GAR1
GDF9
GEMIN2
GEMIN5
GEMIN7
HADHB
HIST3H3
HMGXB3
HNRNPR
HNRNPU
HNRNPUL1
IGHM
ILF3
IMMT
INPP5K
JADE1
KDM1A
KIF5A
KLHL5
KMT2B
KPNB1
LENG8
LRIF1
LSM1
LSM10
LSM11
LSM2
LSM3
LSM4
LSM5
LSM6
LSM7
MAST2
MED31
MKI67
MPP1
MRPL37
MSH2
NGFR
NKIRAS2
NMT2
OSTF1
PDE4DIP
PKM
PLXNA3
POLR2A
POP7
PSME1
QARS
RBBP4
RBBP6
RBFOX2
RBM48
RN7SL1
RNU1-1
RNU2-1
RPL13
RPS2
RXRA
SDF4
SEMA5B
SETDB1
SMC5
SMN2
SNRPB
SNRPD1
SNRPD2
SNRPD3
SNRPE
SNUPN
SP110
STRAP
STXBP2
STXBP3
SULT1A3
SUMO3
SYNCRIP
TAF1C
TIAL1
TLE1
TMSB4X
TP53
TRMT2A
TUBA1A
TUBB3
UCHL1
UNC119
USP4
WDR18
WDR73
WDYHV1
WIZ
ZBTB16
ZNF431
ZRANB2
ZXDC
12 interactors:
APP
ATXN1
CIITA
JTB
NR1H2
NR1H3
POGZ
RORA
SH3GL2
SMN1
TK1
WDR5
Entrez ID
6606
79364
HPRD ID
02646
14420
Ensembl ID
ENSG00000172062
ENSG00000070476
Uniprot IDs
B4DP61
Q16637
Q2QGD7
PDB IDs
1G5V
1MHN
2LEH
3S6N
4A4E
4A4G
4GLI
Enriched GO Terms of Interacting Partners
?
MRNA Processing
RNA Splicing
MRNA Metabolic Process
RNA Processing
RNA Splicing, Via Transesterification Reactions
MRNA Splicing, Via Spliceosome
RNA Metabolic Process
Spliceosomal SnRNP Assembly
Nucleobase-containing Compound Metabolic Process
Gene Expression
Cellular Nitrogen Compound Metabolic Process
Cellular Aromatic Compound Metabolic Process
Heterocycle Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Ribonucleoprotein Complex Assembly
Ribonucleoprotein Complex Biogenesis
NcRNA Metabolic Process
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Cellular Macromolecular Complex Assembly
Histone MRNA Metabolic Process
Metabolic Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Cellular Process
Nuclear-transcribed MRNA Catabolic Process
Posttranscriptional Regulation Of Gene Expression
Cellular Component Assembly
MRNA Catabolic Process
RNA Catabolic Process
CRD-mediated MRNA Stabilization
Regulation Of Protein Metabolic Process
Termination Of RNA Polymerase II Transcription
Regulation Of Cellular Protein Metabolic Process
DNA-templated Transcription, Termination
RNA Biosynthetic Process
MRNA 3'-end Processing
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Transcription, DNA-templated
RNA 3'-end Processing
Regulation Of Mitotic Cell Cycle Phase Transition
Spliceosomal Complex Assembly
Negative Regulation Of Cellular Metabolic Process
Regulation Of Cell Cycle Phase Transition
Developmental Process
Regulation Of Metabolic Process
Cellular Macromolecule Catabolic Process
Cell Differentiation
Catabolic Process
Regulation Of Cholesterol Homeostasis
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Pinocytosis
Intracellular Receptor Signaling Pathway
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Negative Regulation Of Cholesterol Storage
Negative Regulation Of Interferon-gamma-mediated Signaling Pathway
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Steroid Hormone Mediated Signaling Pathway
Positive Regulation Of Cholesterol Efflux
Lipid Homeostasis
Positive Regulation Of Fatty Acid Biosynthetic Process
Positive Regulation Of Lipoprotein Lipase Activity
Positive Regulation Of Triglyceride Biosynthetic Process
Positive Regulation Of Cholesterol Transport
Negative Regulation Of Macrophage Derived Foam Cell Differentiation
RNA Metabolic Process
Hormone-mediated Signaling Pathway
Negative Regulation Of Lipid Storage
Regulation Of Cholesterol Efflux
Regulation Of Triglyceride Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Interferon-gamma-mediated Signaling Pathway
Gene Expression
Regulation Of Response To Interferon-gamma
Negative Regulation Of Lipid Transport
Response To Steroid Hormone
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Macrophage Activation
Transcription Initiation From RNA Polymerase II Promoter
Cellular Response To Steroid Hormone Stimulus
Regulation Of Cellular Ketone Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Endocytosis
Negative Regulation Of Signal Transduction
Positive Regulation Of Fatty Acid Metabolic Process
Regulation Of Fatty Acid Biosynthetic Process
Regulation Of Cholesterol Transport
Triglyceride Homeostasis
Acylglycerol Homeostasis
Regulation Of Triglyceride Metabolic Process
Negative Regulation Of Innate Immune Response
Negative Regulation Of Cytokine-mediated Signaling Pathway
Negative Regulation Of Signaling
Tagcloud
?
atrophy
centromeric
compensate
copies
copy
degeneration
deletions
detectable
display
donor
easily
exon
fails
fatal
harbor
hindering
homozygous
infant
intragenic
italian
modifier
muscular
null
predictable
sma
smn2
splice
unusually
weakness
Tagcloud (Difference)
?
atrophy
centromeric
compensate
copies
copy
degeneration
deletions
detectable
display
donor
easily
exon
fails
fatal
harbor
hindering
homozygous
infant
intragenic
italian
modifier
muscular
null
predictable
sma
smn2
splice
unusually
weakness
Tagcloud (Intersection)
?