SMN1 and APLP1

  • Number of citations of the paper that reports this interaction (PMID 21900206)
  • 27
  • Data Source:
  • BioGRID (two hybrid)

SMN1

APLP1

Gene Name survival of motor neuron 1, telomeric amyloid beta (A4) precursor-like protein 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 136 interactors: A1BG A2M ACTB ACTL6B ADAMTS10 AGAP1 APLP1 ARFGAP1 ATP5B ATP6V1A BAG6 BCL2 C19orf60 CARHSP1 CCDC90B CENPB COIL COL4A2 COL4A5 COPS6 CPNE6 CRIP2 CSAD DDAH2 DDX20 DHX9 DMPK DOCK7 DUS2 DYNC1I1 EEF1A1 EIF3G EXT2 EZH2 FAM20C FBL FGB FLAD1 FUBP1 GAPDH GAR1 GDF9 GEMIN2 GEMIN5 GEMIN7 HADHB HIST3H3 HMGXB3 HNRNPR HNRNPU HNRNPUL1 IGHM ILF3 IMMT INPP5K JADE1 KDM1A KIF5A KLHL5 KMT2B KPNB1 LENG8 LRIF1 LSM1 LSM10 LSM11 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MAST2 MED31 MKI67 MPP1 MRPL37 MSH2 NGFR NKIRAS2 NMT2 OSTF1 PDE4DIP PKM PLXNA3 POLR2A POP7 PSME1 QARS RBBP4 RBBP6 RBFOX2 RBM48 RN7SL1 RNU1-1 RNU2-1 RPL13 RPS2 RXRA SDF4 SEMA5B SETDB1 SMC5 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNUPN SP110 STRAP STXBP2 STXBP3 SULT1A3 SUMO3 SYNCRIP TAF1C TIAL1 TLE1 TMSB4X TP53 TRMT2A TUBA1A TUBB3 UCHL1 UNC119 USP4 WDR18 WDR73 WDYHV1 WIZ ZBTB16 ZNF431 ZRANB2 ZXDC 43 interactors: ANXA7 APBB1 APBB3 CDK4 CDKN1A CDKN2C CRCT1 CSNK2B DAB1 DAB2 EEF1A1 EIF2S2 GDF9 GSTM4 HAP1 HLA-DQA1 HSPE1 ING5 KAT5 LRIF1 MPHOSPH6 NACA PCDHA4 PHF10 PIN1 PNP PRNP RAP1B RBM48 RCC1 SAT1 SETDB1 SMN1 SNCA STX5 TCF21 TK1 TMSB4X TOE1 TSC22D1 UTP14A VIM ZNF24
Entrez ID 6606 333
HPRD ID 02646 00102
Ensembl ID ENSG00000172062 ENSG00000105290
Uniprot IDs B4DP61 Q16637 F5GZ08 P51693
PDB IDs 1G5V 1MHN 2LEH 3S6N 4A4E 4A4G 4GLI 3PMR 3Q7G 3Q7L 3QMK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
atrophy  centromeric  compensate  copies  copy  degeneration  deletions  detectable  display  donor  easily  exon  fails  fatal  harbor  hindering  homozygous  infant  intragenic  italian  modifier  muscular  null  predictable  sma  smn2  splice  unusually  weakness 
abundance  allocated  analyzing  aplp2  app  apparatus  appsalpha  attached  compartments  corresponds  endosomal  golgi  homozygous  immunopurification  impacts  knockout  ko  organellar  pool  presynaptic  residing  sv2  sv2a  synaptic  synaptogamin  synaptophysin  synaptotagmin  vesicle  zone 
Tagcloud (Difference) ?
atrophy  centromeric  compensate  copies  copy  degeneration  deletions  detectable  display  donor  easily  exon  fails  fatal  harbor  hindering  infant  intragenic  italian  modifier  muscular  null  predictable  sma  smn2  splice  unusually  weakness 
abundance  allocated  analyzing  aplp2  app  apparatus  appsalpha  attached  compartments  corresponds  endosomal  golgi  immunopurification  impacts  knockout  ko  organellar  pool  presynaptic  residing  sv2  sv2a  synaptic  synaptogamin  synaptophysin  synaptotagmin  vesicle  zone 
Tagcloud (Intersection) ?
homozygous