Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
MCM10 and TRIM37
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
MCM10
TRIM37
Gene Name
minichromosome maintenance complex component 10
tripartite motif containing 37
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytoplasm
Peroxisome
Cytosol
Aggresome
ESC/E(Z) Complex
Perinuclear Region Of Cytoplasm
Molecular Function
DNA Binding
Protein Binding
Identical Protein Binding
Metal Ion Binding
Chromatin Binding
Ubiquitin-protein Transferase Activity
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Ligase Activity
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Ubiquitin Protein Ligase Activity
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
DNA Replication
Cell Proliferation
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of NF-kappaB Transcription Factor Activity
Histone H2A Monoubiquitination
Histone H2A-K119 Monoubiquitination
Negative Regulation Of Centriole Replication
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Autoubiquitination
Aggresome Assembly
Pathways
G2/M Checkpoints
Activation of the pre-replicative complex
DNA Replication Pre-Initiation
Regulation of DNA replication
M/G1 Transition
Activation of the pre-replicative complex
Cell Cycle, Mitotic
G1/S Transition
Activation of ATR in response to replication stress
Cell Cycle Checkpoints
Removal of licensing factors from origins
Mitotic G1-G1/S phases
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Testicular germ cell tumor (
23666239
)
Protein-Protein Interactions
32 interactors:
APP
CALCOCO2
CCDC85B
CCND1
CCND3
CDC45
CDC5L
CDC6
CDC7
CDK6
CDKN1A
CDKN2A
CEP70
CEP72
DPPA2
GOLGA2
HAUS1
HOOK2
IKBKG
KRT15
MCM2
MCM3
MCM6
MCM7
NINL
ORC2
ORC3
ORC4
TRIM37
VPRBP
ZBTB43
ZBTB8A
59 interactors:
ANKRD11
APEX2
APTX
ARNT2
BYSL
CCDC33
CDC20B
CDK5RAP2
COPB1
CWF19L2
DDX6
DLGAP5
EWSR1
FAM107A
FAM124B
FAM161A
FAM50B
FXR2
KAT5
KIAA0408
KIF9
LTBR
MAGEB18
MCM10
MCRS1
NGFR
NUDT18
PBK
PNKP
PRC1
RASD1
RHPN1
RIBC2
RPL9
SCNM1
SSX2IP
TANK
TCEB3B
TNFRSF1B
TRAF1
TRAF2
TRAF3
TRAF4
TRAF5
TRAF6
UBASH3A
UBB
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2U
ZMAT2
ZNF329
ZNF417
ZNF655
Entrez ID
55388
4591
HPRD ID
11297
05463
Ensembl ID
ENSG00000065328
ENSG00000108395
Uniprot IDs
Q7L590
A8K0V9
A8K8U4
F8WEE6
O94972
PDB IDs
3LRQ
Enriched GO Terms of Interacting Partners
?
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Mitotic Cell Cycle Process
Cell Cycle
Cell Cycle Process
DNA Replication Initiation
DNA-dependent DNA Replication
DNA Replication
DNA Strand Elongation Involved In DNA Replication
DNA Strand Elongation
Regulation Of Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle
DNA Metabolic Process
Regulation Of Cell Cycle Process
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle Phase Transition
Macromolecule Biosynthetic Process
Positive Regulation Of Cell Cycle Process
Regulation Of Cell Cycle
DNA Duplex Unwinding
DNA Geometric Change
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
DNA Unwinding Involved In DNA Replication
Cellular Nitrogen Compound Metabolic Process
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Mitotic Cell Cycle
Regulation Of Cell Cycle G2/M Phase Transition
Regulation Of Mitotic Cell Cycle
Cell Division
Biosynthetic Process
DNA Conformation Change
Double-strand Break Repair Via Break-induced Replication
Nitrogen Compound Metabolic Process
Organelle Organization
Chromosome Organization
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Cellular Response To DNA Damage Stimulus
Cell Cycle Checkpoint
G2/M Transition Of Mitotic Cell Cycle
Negative Regulation Of Cell Cycle
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Phosphorylation
Protein Polyubiquitination
TRIF-dependent Toll-like Receptor Signaling Pathway
Protein K48-linked Ubiquitination
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Positive Regulation Of Innate Immune Response
Cellular Macromolecule Catabolic Process
Regulation Of Innate Immune Response
Protein K11-linked Ubiquitination
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Protein K63-linked Ubiquitination
Cellular Response To Stress
Catabolic Process
Polynucleotide 3' Dephosphorylation
Apoptotic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Protein Catabolic Process
Immune Response-regulating Signaling Pathway
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of DNA-templated Transcription In Response To Stress
Programmed Cell Death
I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Mitotic Cell Cycle Phase Transition
Cellular Response To DNA Damage Stimulus
Regulation Of Cell Cycle Phase Transition
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteolysis
Cell Death
Death
Activation Of NF-kappaB-inducing Kinase Activity
Modification-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of NIK/NF-kappaB Signaling
Cellular Protein Catabolic Process
DNA Repair
Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Proteolysis
Regulation Of Stress-activated MAPK Cascade
NIK/NF-kappaB Signaling
Regulation Of NIK/NF-kappaB Signaling
Regulation Of Metabolic Process
Tagcloud
?
cerevisiae
deadpan
delay
discs
driver
drosophila
enhancer
eye
eyes
gal4
gmr
imaginal
interference
involvement
klingon
knockdown
lacz
maintenance
mini
monitor
morphology
ommatidia
phases
photoreceptor
r7
replication
rough
surprisingly
Tagcloud (Difference)
?
cerevisiae
deadpan
delay
discs
driver
drosophila
enhancer
eye
eyes
gal4
gmr
imaginal
interference
involvement
klingon
knockdown
lacz
maintenance
mini
monitor
morphology
ommatidia
phases
photoreceptor
r7
replication
rough
surprisingly
Tagcloud (Intersection)
?