MCM10 and HAUS1

Number of citations of the paper that reports this interaction (PMID 15232106)
88

Data Source:
HPRD (in vitro)

		MCM10	HAUS1
Gene Name		minichromosome maintenance complex component 10	HAUS augmin-like complex, subunit 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm	Spindle Pole Cytoplasm Centrosome Microtubule HAUS Complex
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding Metal Ion Binding	Molecular_function Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Replication Cell Proliferation	Mitotic Nuclear Division Spindle Assembly Centrosome Organization Cell Division
Pathways		G2/M Checkpoints Activation of the pre-replicative complex DNA Replication Pre-Initiation Regulation of DNA replication M/G1 Transition Activation of the pre-replicative complex Cell Cycle, Mitotic G1/S Transition Activation of ATR in response to replication stress Cell Cycle Checkpoints Removal of licensing factors from origins Mitotic G1-G1/S phases
Drugs
Diseases
GWAS
Protein-Protein Interactions		32 interactors: APP CALCOCO2 CCDC85B CCND1 CCND3 CDC45 CDC5L CDC6 CDC7 CDK6 CDKN1A CDKN2A CEP70 CEP72 DPPA2 GOLGA2 HAUS1 HOOK2 IKBKG KRT15 MCM2 MCM3 MCM6 MCM7 NINL ORC2 ORC3 ORC4 TRIM37 VPRBP ZBTB43 ZBTB8A	66 interactors: AK8 ARFIP2 BLOC1S6 C3orf62 CAGE1 CCDC114 CCDC136 CCDC53 CCDC57 CCHCR1 CDR2 CEP170P1 CEP44 CEP55 CEP57L1 CEP63 CEP70 DCTN2 DMD DTNBP1 FGFR1OP2 GOLGA2 IFIT3 IFT20 INCA1 KDM1A KIFC3 KRT15 KRT18 KRT19 KRT31 KRT38 KRT40 KXD1 LDOC1 LURAP1 MAD1L1 MAGEA6 MCM10 MCM3 MED4 MED7 MIPOL1 MTUS2 NDC80 NECAB2 NINL NUP54 NUP62 PDE4DIP SPAG5 SPERT STX11 SYCE1 SYCE3 TFIP11 TFPT TRAF1 TRIM23 TRIM27 TRIM54 TRIM69 TSG101 USHBP1 VPS52 ZNF471
Entrez ID		55388	115106
HPRD ID		11297	16385
Ensembl ID		ENSG00000065328	ENSG00000152240
Uniprot IDs		Q7L590	Q96CS2
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Mitotic Cell Cycle Process Cell Cycle Cell Cycle Process DNA Replication Initiation DNA-dependent DNA Replication DNA Replication DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Cycle DNA Metabolic Process Regulation Of Cell Cycle Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Macromolecule Biosynthetic Process Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle DNA Duplex Unwinding DNA Geometric Change Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity DNA Unwinding Involved In DNA Replication Cellular Nitrogen Compound Metabolic Process Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Mitotic Cell Cycle Cell Division Biosynthetic Process DNA Conformation Change Double-strand Break Repair Via Break-induced Replication Nitrogen Compound Metabolic Process Organelle Organization Chromosome Organization Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Cellular Response To DNA Damage Stimulus Cell Cycle Checkpoint G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Phosphorylation	Organelle Organization Cell Cycle Cell Cycle Process Mitotic Cell Cycle Mitotic Cell Cycle Process Cell Division Microtubule-based Process Cytoskeleton Organization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Organelle Localization Protein Localization G2/M Transition Of Mitotic Cell Cycle Spindle Organization Establishment Of Protein Localization Cellular Pigmentation Cellular Localization Mitotic Nuclear Division Establishment Of Organelle Localization Protein Transport Anterograde Synaptic Vesicle Transport Establishment Of Localization In Cell Establishment Of Vesicle Localization Post-Golgi Vesicle-mediated Transport Vesicle Organization Viral Process Melanosome Organization Vesicle Localization Pigment Granule Organization Intracellular Transport Synaptonemal Complex Assembly Synaptonemal Complex Organization Chromosome Segregation Anterograde Axon Cargo Transport Synaptic Vesicle Transport Cellular Component Assembly Pigmentation Membrane Organization Microtubule Cytoskeleton Organization Endomembrane System Organization Actin Filament-based Process Spliceosomal Complex Disassembly Regulation Of Primitive Erythrocyte Differentiation Regulation Of Metaphase Plate Congression Golgi To Plasma Membrane CFTR Protein Transport Opsin Transport Melanosome Transport Mitotic Nuclear Envelope Disassembly Regulation Of Organelle Organization Microtubule-based Transport
Tagcloud ?		cerevisiae deadpan delay discs driver drosophila enhancer eye eyes gal4 gmr imaginal interference involvement klingon knockdown lacz maintenance mini monitor morphology ommatidia phases photoreceptor r7 replication rough surprisingly
Tagcloud (Difference) ?		cerevisiae deadpan delay discs driver drosophila enhancer eye eyes gal4 gmr imaginal interference involvement klingon knockdown lacz maintenance mini monitor morphology ommatidia phases photoreceptor r7 replication rough surprisingly
Tagcloud (Intersection) ?