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MCM10 and CCDC85B
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
HPRD
(two hybrid)
MCM10
CCDC85B
Gene Name
minichromosome maintenance complex component 10
coiled-coil domain containing 85B
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Nucleus
Cytoplasm
Centrosome
Molecular Function
DNA Binding
Protein Binding
Identical Protein Binding
Metal Ion Binding
Protein Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
DNA Replication
Cell Proliferation
Transcription, DNA-templated
Cell Differentiation
Negative Regulation Of Cell Growth
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Transcription, DNA-templated
Pathways
G2/M Checkpoints
Activation of the pre-replicative complex
DNA Replication Pre-Initiation
Regulation of DNA replication
M/G1 Transition
Activation of the pre-replicative complex
Cell Cycle, Mitotic
G1/S Transition
Activation of ATR in response to replication stress
Cell Cycle Checkpoints
Removal of licensing factors from origins
Mitotic G1-G1/S phases
Drugs
Diseases
GWAS
Protein-Protein Interactions
32 interactors:
APP
CALCOCO2
CCDC85B
CCND1
CCND3
CDC45
CDC5L
CDC6
CDC7
CDK6
CDKN1A
CDKN2A
CEP70
CEP72
DPPA2
GOLGA2
HAUS1
HOOK2
IKBKG
KRT15
MCM2
MCM3
MCM6
MCM7
NINL
ORC2
ORC3
ORC4
TRIM37
VPRBP
ZBTB43
ZBTB8A
133 interactors:
AGGF1
AKAP17A
AKIRIN2
ALS2CR11
APEX2
AQP1
BEX2
C10orf10
C19orf25
C1orf111
C20orf195
C21orf91
C7orf50
C8orf48
CARD9
CCDC112
CCDC116
CCDC120
CCDC185
CCDC33
CCDC67
CCNK
CDK18
CDKN1A
CEP70
CFAP53
CHCHD3
COPS4
CWC25
DOK5
DTNB
DUSP13
EIF3H
ENKD1
EPS8
EXOC7
EXOC8
EZH2
FAM107A
FAM124B
FAM13C
FAM208B
FAM214B
FAM27E3
FAM50B
FAM74A4
FASTKD5
FBF1
FCHSD2
FXR2
GCC1
GFI1B
GPANK1
HMG20B
HNRNPC
IKZF5
KANSL1
KIAA0408
KRT17
KRT18
KRT20
KRT6A
LDOC1
LMO3
LNX1
LZTS2
MBIP
MCM10
MCRS1
MEAF6
MOAP1
MOB1A
MOB4
NDUFA5
NEK6
NGFRAP1
NIF3L1
NRIP1
NUP54
PBXIP1
PIDD1
PKN1
PLEKHF2
PLOD3
POLR2L
PRC1
PRPF3
PSMA1
PSMC1
PSMC6
PSMF1
RALYL
RBM41
RBM7
RIBC2
RNF8
SCNM1
SETD5
SF3A3
SIX1
SLU7
SMARCD1
SYT17
SYTL4
TCEANC
TCHP
TEAD4
THAP7
TNNI1
TNNT1
TSPYL4
TTC14
TTC25
TUBGCP4
USP2
UTP14A
UTP6
VPS72
ZBTB16
ZBTB5
ZC2HC1C
ZFC3H1
ZFP36
ZNF165
ZNF205
ZNF250
ZNF337
ZNF417
ZNF426
ZNF564
ZNF638
ZNF764
ZNF821
Entrez ID
55388
11007
HPRD ID
11297
16101
Ensembl ID
ENSG00000065328
ENSG00000175602
Uniprot IDs
Q7L590
Q15834
PDB IDs
Enriched GO Terms of Interacting Partners
?
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Mitotic Cell Cycle Process
Cell Cycle
Cell Cycle Process
DNA Replication Initiation
DNA-dependent DNA Replication
DNA Replication
DNA Strand Elongation Involved In DNA Replication
DNA Strand Elongation
Regulation Of Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle
DNA Metabolic Process
Regulation Of Cell Cycle Process
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle Phase Transition
Macromolecule Biosynthetic Process
Positive Regulation Of Cell Cycle Process
Regulation Of Cell Cycle
DNA Duplex Unwinding
DNA Geometric Change
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
DNA Unwinding Involved In DNA Replication
Cellular Nitrogen Compound Metabolic Process
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Mitotic Cell Cycle
Regulation Of Cell Cycle G2/M Phase Transition
Regulation Of Mitotic Cell Cycle
Cell Division
Biosynthetic Process
DNA Conformation Change
Double-strand Break Repair Via Break-induced Replication
Nitrogen Compound Metabolic Process
Organelle Organization
Chromosome Organization
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Cellular Response To DNA Damage Stimulus
Cell Cycle Checkpoint
G2/M Transition Of Mitotic Cell Cycle
Negative Regulation Of Cell Cycle
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Phosphorylation
Gene Expression
RNA Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cell Cycle
RNA Biosynthetic Process
Transcription, DNA-templated
Mitotic Cell Cycle Process
Mitotic Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Signal Transduction Involved In DNA Damage Checkpoint
Regulation Of Cell Cycle Arrest
Regulation Of Gene Expression
Signal Transduction Involved In Cell Cycle Checkpoint
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Nitrogen Compound Metabolic Process
Mitotic G1 DNA Damage Checkpoint
Organelle Organization
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Cellular Metabolic Process
Positive Regulation Of Cell Cycle Arrest
Cell Cycle Process
DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Transcription, DNA-templated
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Apoptotic Process
Macromolecule Biosynthetic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Signal Transduction In Response To DNA Damage
Mitotic DNA Damage Checkpoint
Regulation Of RNA Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Process
Programmed Cell Death
DNA Damage Checkpoint
Regulation Of Mitotic Cell Cycle Phase Transition
RNA Processing
Mitotic DNA Integrity Checkpoint
Cellular Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Regulation Of Cell Cycle Phase Transition
Cell Death
Tagcloud
?
cerevisiae
deadpan
delay
discs
driver
drosophila
enhancer
eye
eyes
gal4
gmr
imaginal
interference
involvement
klingon
knockdown
lacz
maintenance
mini
monitor
morphology
ommatidia
phases
photoreceptor
r7
replication
rough
surprisingly
Tagcloud (Difference)
?
cerevisiae
deadpan
delay
discs
driver
drosophila
enhancer
eye
eyes
gal4
gmr
imaginal
interference
involvement
klingon
knockdown
lacz
maintenance
mini
monitor
morphology
ommatidia
phases
photoreceptor
r7
replication
rough
surprisingly
Tagcloud (Intersection)
?