RABAC1 and RIMS2

Number of citations of the paper that reports this interaction (PubMedID 10707984)
0

Data Source:
HPRD (in vitro, two hybrid)

		RABAC1	RIMS2
Description		Rab acceptor 1	regulating synaptic membrane exocytosis 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Presynapse Glutamatergic Synapse	Plasma Membrane Membrane Presynaptic Membrane Cell Projection Synapse Presynaptic Active Zone Extracellular Exosome Presynaptic Active Zone Cytoplasmic Component
	Molecular Function	Protein Binding Identical Protein Binding GTPase Binding Proline-rich Region Binding	Protein Binding Zinc Ion Binding Small GTPase Binding Transmembrane Transporter Binding Metal Ion Binding Structural Constituent Of Presynaptic Active Zone
	Biological Process		Intracellular Protein Transport Exocytosis Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Synaptic Vesicle Docking Synaptic Vesicle Priming Calcium-ion Regulated Exocytosis Regulation Of Exocytosis Insulin Secretion Cell Differentiation Regulation Of Membrane Potential Maintenance Of Presynaptic Active Zone Structure Calcium Ion-regulated Exocytosis Of Neurotransmitter Spontaneous Neurotransmitter Secretion Positive Regulation Of Inhibitory Postsynaptic Potential Positive Regulation Of Dendrite Extension Regulation Of Synaptic Vesicle Exocytosis Positive Regulation Of Excitatory Postsynaptic Potential
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287)	Cocaine dependence ( 23958962) Dietary fat liking ( 32516399) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) High density lipoprotein cholesterol levels ( 30498476) Monoclonal gammopathy of undetermined significance ( 30737484) Multiple system atrophy (pathologically confirmed) ( 27629089) Parkinson's disease progression (cognitive) ( 33958783)
Interacting Genes		98 interacting genes: ABHD4 AQP6 C6orf47 CMTM3 COQ8A CRB3 CREB3 CYB5R3 CYBRD1 DUSP12 EI24 EMP1 F11R FHIP1B FXR1 FXR2 GDI1 GPR152 HRAS HRG HSD17B13 LEMD3 LMNA LNX1 LTBR MAD2L1 MCF2L MIEF2 NAT14 NDRG2 NDRG4 NIF3L1 NR3C2 NTAQ1 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP2 REEP5 RETREG3 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RNF5 RPS20 RRAS2 S100B SGK1 SH3GL3 SH3GLB1 SLAMF6 SLC10A1 SLC18A1 SNCA SNX1 SNX10 SNX11 SNX15 SNX17 SNX8 SPG21 SSR3 STIM1 STOML2 SYT16 TMEM115 TMEM14B TMEM42 TMX2 TNIP1 TRIM32 TSHR TUBB2A TXN2 UBE2I VAMP2 VIM VTA1 WIPI2 ZFYVE21	13 interacting genes: ABCA1 CACNA1S EGFR RAB27A RAB3A RAB3B RAB3C RAB3D RAB8A RABAC1 RAPGEF4 RPH3AL YWHAH
Entrez ID		10567	9699
HPRD ID		05375	09436
Ensembl ID		ENSG00000105404	ENSG00000176406
Uniprot IDs		Q9UI14	A0A8Q3SIU4 A0A8Q3SJ53 A0A994J503 A0A994J5M6 A0A994J7W6 F8W6W8 Q9UQ26
PDB IDs			1V27 1WFG
Enriched GO Terms of Interacting Partners?		GTPase Activity GTP Binding GDP Binding Membrane Endosome G Protein Activity Establishment Of Localization In Cell Vesicle-mediated Transport Protein Transport Intracellular Protein Localization Establishment Of Protein Localization Cellular Localization Intracellular Protein Transport Protein Binding Endosomal Transport Regulation Of Neuronal Synaptic Plasticity Lipid Binding Secretory Granule Membrane Intracellular Transport Phosphatidylinositol Binding Endocytosis Vesicle Organization Regulation Of Long-term Neuronal Synaptic Plasticity Early Endosome Regulation Of Cellular Component Organization Endosome Organization Regulation Of Vesicle-mediated Transport Vesicle-mediated Transport In Synapse Synaptic Vesicle Exocytosis Localization Within Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Rab Protein Signal Transduction Import Into Cell Early Endosome To Golgi Transport Early Endosome Membrane Endomembrane System Cytoplasmic Vesicle Endoplasmic Reticulum Membrane Organelle Organization Synaptic Vesicle Membrane Identical Protein Binding Autophagosome Assembly Plasma Membrane To Endosome Transport Small GTPase-mediated Signal Transduction Regulation Of Synaptic Plasticity Establishment Of Organelle Localization Autophagosome Organization Endosome Membrane Endocytic Vesicle Organelle Localization	Myosin V Binding Exocytosis Secretion By Cell Secretion Regulation Of Exocytosis Establishment Of Protein Localization Synaptic Vesicle Protein Transport GTP-dependent Protein Binding Endosome Positive Regulation Of Regulated Secretory Pathway Regulation Of Transport Vesicle-mediated Transport GTPase Activity Regulation Of Vesicle-mediated Transport Regulation Of Secretion By Cell Intracellular Protein Localization GTP Binding Regulation Of Secretion Positive Regulation Of Exocytosis Positive Regulation Of Transport Nucleotide Binding Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Regulation Of Regulated Secretory Pathway Positive Regulation Of Secretion By Cell Positive Regulation Of Secretion Plasma Membrane Membrane Peptide Secretion GDP Binding Presynapse Golgi Apparatus Regulation Of Synaptic Vesicle Cycle Peptide Transport Antigen Processing And Presentation Small GTPase Binding Regulation Of Biological Quality Secretory Granule Regulated Exocytosis Vesicle Organization Intracellular Vesicle Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Perinuclear Region Of Cytoplasm Amide Transport Signal Release Calcium-ion Regulated Exocytosis Regulation Of Vesicle Fusion Synaptic Vesicle Transport
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