RABAC1 and TMX2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RABAC1	TMX2
Description		Rab acceptor 1	thioredoxin related transmembrane protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Presynapse Glutamatergic Synapse	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Mitochondrial Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site
	Molecular Function	Protein Binding Identical Protein Binding GTPase Binding Proline-rich Region Binding	Protein Binding Disulfide Oxidoreductase Activity Identical Protein Binding
	Biological Process		Brain Development
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287)	Autism spectrum disorder or schizophrenia ( 28540026) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 29255261) Problematic alcohol use ( 32451486) Reticulocyte count ( 32888494) Schizophrenia ( 25056061 29483656)
Interacting Genes		98 interacting genes: ABHD4 AQP6 C6orf47 CMTM3 COQ8A CRB3 CREB3 CYB5R3 CYBRD1 DUSP12 EI24 EMP1 F11R FHIP1B FXR1 FXR2 GDI1 GPR152 HRAS HRG HSD17B13 LEMD3 LMNA LNX1 LTBR MAD2L1 MCF2L MIEF2 NAT14 NDRG2 NDRG4 NIF3L1 NR3C2 NTAQ1 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP2 REEP5 RETREG3 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RNF5 RPS20 RRAS2 S100B SGK1 SH3GL3 SH3GLB1 SLAMF6 SLC10A1 SLC18A1 SNCA SNX1 SNX10 SNX11 SNX15 SNX17 SNX8 SPG21 SSR3 STIM1 STOML2 SYT16 TMEM115 TMEM14B TMEM42 TMX2 TNIP1 TRIM32 TSHR TUBB2A TXN2 UBE2I VAMP2 VIM VTA1 WIPI2 ZFYVE21	163 interacting genes: AGPAT3 AGPAT4 AGPAT5 AIG1 AQP6 ARV1 ASGR1 ASPH ATXN1 BDKRB1 BET1 BNIP1 BNIP2 BNIP3 BRICD5 BTN2A2 C2CD2L CCDC167 CCL2 CD81 CDIPT CDS2 CMTM7 COL8A2 COMMD8 COX20 CTSA CTXN3 CXCL16 CXorf66 CYBC1 CYP4F2 DERL1 DGAT2L6 EMD EMP3 F2RL1 FA2H FAM177A1 FAM241B FAM3C FAXDC2 FDFT1 FUNDC2 FXYD6-FXYD2 GIMAP1 GIMAP5 GJB2 HACD2 HHATL HMOX1 HMOX2 HSD17B11 HSD17B13 HTATIP2 IER3 IER3IP1 IGFBP5 INSIG2 ITGAM LEPROT LEPROTL1 LHFPL5 LRAT MALL MFF MGLL MGST3 MIP MLN MS4A1 MTNR1A NAT8 NDUFA3 NINJ2 NRM NSDHL NSG1 ORMDL2 OTULINL PAEP PEDS1-UBE2V1 PEX16 PKMYT1 PLP2 PNLIPRP1 PRAF2 PRB1 PTAFR PTPN9 RABAC1 REEP2 REEP4 RFT1 RNF24 RTP2 RUSF1 SACM1L SCAMP5 SCD SELENOK SERF1A SERF1B SERP2 SFT2D1 SFXN1 SFXN3 SLC22A2 SLC29A2 SLC35A1 SLC67A1 SLC71A2 SMAGP SMCO4 SMIM1 STATH STX12 STX3 STX7 THBD THSD7B TMBIM6 TMEM115 TMEM120A TMEM120B TMEM121 TMEM128 TMEM140 TMEM14B TMEM14C TMEM176A TMEM201 TMEM203 TMEM208 TMEM222 TMEM239 TMEM254 TMEM31 TMEM50B TMEM51 TMEM65 TMEM71 TMEM86B TMEM97 TPRG1 TRAM1L1 TREX1 TSNARE1 TSPAN2 TVP23B UBE2J1 UNC93A VAMP1 VAMP3 VAMP4 VAMP5 VAPA VAPB WFDC2 YIF1A YIPF1 YIPF2 YIPF6
Entrez ID		10567	51075
HPRD ID		05375	07159
Ensembl ID		ENSG00000105404	ENSG00000213593
Uniprot IDs		Q9UI14	Q9Y320
PDB IDs			2DJ0
Enriched GO Terms of Interacting Partners?		GTPase Activity GTP Binding GDP Binding Membrane Endosome G Protein Activity Establishment Of Localization In Cell Vesicle-mediated Transport Protein Transport Intracellular Protein Localization Establishment Of Protein Localization Cellular Localization Intracellular Protein Transport Protein Binding Endosomal Transport Regulation Of Neuronal Synaptic Plasticity Lipid Binding Secretory Granule Membrane Intracellular Transport Phosphatidylinositol Binding Endocytosis Vesicle Organization Regulation Of Long-term Neuronal Synaptic Plasticity Early Endosome Regulation Of Cellular Component Organization Endosome Organization Regulation Of Vesicle-mediated Transport Vesicle-mediated Transport In Synapse Synaptic Vesicle Exocytosis Localization Within Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Rab Protein Signal Transduction Import Into Cell Early Endosome To Golgi Transport Early Endosome Membrane Endomembrane System Cytoplasmic Vesicle Endoplasmic Reticulum Membrane Organelle Organization Synaptic Vesicle Membrane Identical Protein Binding Autophagosome Assembly Plasma Membrane To Endosome Transport Small GTPase-mediated Signal Transduction Regulation Of Synaptic Plasticity Establishment Of Organelle Localization Autophagosome Organization Endosome Membrane Endocytic Vesicle Organelle Localization	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNARE Complex SNAP Receptor Activity Cortical Endoplasmic Reticulum Protein Binding CDP-diacylglycerol Metabolic Process Vesicle-mediated Transport Lipid Biosynthetic Process Membrane Organization Nuclear Envelope Endomembrane System Membrane Docking CDP-diacylglycerol Biosynthetic Process Organelle Fusion Organelle Membrane Fusion Intracellular Transport Lipid Metabolic Process Organelle Localization By Membrane Tethering Golgi Membrane Membrane Fusion Endoplasmic Reticulum Organization Cellular Localization Establishment Of Localization In Cell Sterol Biosynthetic Process Vesicle Fusion Golgi Trans Cisterna Golgi Medial Cisterna Golgi Vesicle Transport Heme Oxidation Heme Oxygenase (decyclizing) Activity Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Nuclear Inner Membrane Response To Oxygen-glucose Deprivation Regulation Of Cellular Localization Amyloid Fibril Formation Mitochondrial Outer Membrane Steroid Biosynthetic Process Monoatomic Ion Transmembrane Transporter Activity SNARE Complex Assembly Glycerolipid Metabolic Process FFAT Motif Binding Steroid Dehydrogenase Activity Serine Import Into Mitochondrion Vesicle Docking Golgi Apparatus Heme Metabolic Process Spindle Pole Centrosome Cholesterol Biosynthetic Process
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