RABAC1 and RAB4B

Number of citations of the paper that reports this interaction (PubMedID 10329441)
0

Data Source:
HPRD (two hybrid)

		RABAC1	RAB4B
Description		Rab acceptor 1	RAB4B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Presynapse Glutamatergic Synapse	Endosome Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Secretory Granule Membrane Early Endosome Membrane Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Protein Binding Identical Protein Binding GTPase Binding Proline-rich Region Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding
	Biological Process		Protein Transport Vesicle-mediated Transport Regulation Of Endocytosis Rab Protein Signal Transduction Endosomal Vesicle Fusion Early Endosome To Golgi Transport D-glucose Import
Pathways			Neutrophil degranulation RAB geranylgeranylation MET receptor recycling
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287)	Carotid intima media thickness (mean) ( 31801372) Chronic obstructive pulmonary disease ( 22080838 28166215) Emphysema imaging phenotypes ( 26030696) Eosinophil percentage of white cells ( 32888494) Hematocrit ( 32888494) Hemoglobin ( 32888494) Kawasaki disease ( 22081228) Red blood cell count ( 32888494) Smoking behaviour (cigarettes smoked per day) ( 30617275)
Interacting Genes		98 interacting genes: ABHD4 AQP6 C6orf47 CMTM3 COQ8A CRB3 CREB3 CYB5R3 CYBRD1 DUSP12 EI24 EMP1 F11R FHIP1B FXR1 FXR2 GDI1 GPR152 HRAS HRG HSD17B13 LEMD3 LMNA LNX1 LTBR MAD2L1 MCF2L MIEF2 NAT14 NDRG2 NDRG4 NIF3L1 NR3C2 NTAQ1 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP2 REEP5 RETREG3 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RNF5 RPS20 RRAS2 S100B SGK1 SH3GL3 SH3GLB1 SLAMF6 SLC10A1 SLC18A1 SNCA SNX1 SNX10 SNX11 SNX15 SNX17 SNX8 SPG21 SSR3 STIM1 STOML2 SYT16 TMEM115 TMEM14B TMEM42 TMX2 TNIP1 TRIM32 TSHR TUBB2A TXN2 UBE2I VAMP2 VIM VTA1 WIPI2 ZFYVE21	9 interacting genes: BOLA2 BOLA2B CDC45 EXOC5 GARIN6 RAB7A RABAC1 RABEP1 VPS52
Entrez ID		10567	53916
HPRD ID		05375	11473
Ensembl ID		ENSG00000105404	ENSG00000167578
Uniprot IDs		Q9UI14	P61018
PDB IDs			2O52
Enriched GO Terms of Interacting Partners?		GTPase Activity GTP Binding GDP Binding Membrane Endosome G Protein Activity Establishment Of Localization In Cell Vesicle-mediated Transport Protein Transport Intracellular Protein Localization Establishment Of Protein Localization Cellular Localization Intracellular Protein Transport Protein Binding Endosomal Transport Regulation Of Neuronal Synaptic Plasticity Lipid Binding Secretory Granule Membrane Intracellular Transport Phosphatidylinositol Binding Endocytosis Vesicle Organization Regulation Of Long-term Neuronal Synaptic Plasticity Early Endosome Regulation Of Cellular Component Organization Endosome Organization Regulation Of Vesicle-mediated Transport Vesicle-mediated Transport In Synapse Synaptic Vesicle Exocytosis Localization Within Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Rab Protein Signal Transduction Import Into Cell Early Endosome To Golgi Transport Early Endosome Membrane Endomembrane System Cytoplasmic Vesicle Endoplasmic Reticulum Membrane Organelle Organization Synaptic Vesicle Membrane Identical Protein Binding Autophagosome Assembly Plasma Membrane To Endosome Transport Small GTPase-mediated Signal Transduction Regulation Of Synaptic Plasticity Establishment Of Organelle Localization Autophagosome Organization Endosome Membrane Endocytic Vesicle Organelle Localization	Vesicle-mediated Transport To The Plasma Membrane Post-Golgi Vesicle-mediated Transport Iron-sulfur Cluster Assembly Complex [2Fe-2S] Cluster Assembly Iron-sulfur Cluster Assembly 2 Iron, 2 Sulfur Cluster Binding Localization Within Membrane Protein Localization To Cell Periphery Cell Redox Homeostasis Golgi Vesicle Transport Embryonic Ectodermal Digestive Tract Development Synaptic Vesicle Recycling Via Endosome Protein Localization To Membrane Mitotic DNA Replication Preinitiation Complex Assembly Golgi To Plasma Membrane Transport Intracellular Iron Ion Homeostasis Iron-sulfur Cluster Binding Endocytic Recycling Negative Regulation Of Intralumenal Vesicle Formation Membrane Docking Epidermal Growth Factor Catabolic Process Intracellular Monoatomic Ion Homeostasis Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Intracellular Monoatomic Cation Homeostasis DNA Replication Preinitiation Complex Retrograde Transport, Endosome To Golgi Protein Transport Monoatomic Cation Homeostasis Lipophagy DNA Replication Preinitiation Complex Assembly Monoatomic Ion Homeostasis Lysosomal Transport Cytosolic Transport Vesicle-mediated Transport Negative Regulation Of Exosomal Secretion Intracellular Chemical Homeostasis Recycling Endosome GARP Complex EARP Complex Ectodermal Cell Differentiation Protein To Membrane Docking Glutamatergic Synapse Regulation Of Endosome Organization Membrane Fusion Establishment Of Protein Localization Alveolar Lamellar Body Vacuolar Transport Cellular Homeostasis Phagosome Acidification Membrane Organization
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