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PCNT and YWHAH
Number of citations of the paper that reports this interaction (PubMedID
35914814
)
83
Data Source:
BioGRID
(two hybrid)
PCNT
YWHAH
Description
pericentrin
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Centrosome
Centriole
Microtubule Organizing Center
Cytosol
Cytoskeleton
Microtubule
Membrane
Centriolar Satellite
Cytoplasm
Mitochondrion
Cytosol
Plasma Membrane
Intercalated Disc
Synapse
Extracellular Exosome
Presynapse
Glutamatergic Synapse
Cerebellar Granule Cell To Purkinje Cell Synapse
Molecular Function
Protein Binding
Calmodulin Binding
Molecular Adaptor Activity
Actin Binding
Insulin-like Growth Factor Receptor Binding
Protein Binding
Sodium Channel Regulator Activity
Enzyme Binding
Protein Domain Specific Binding
Nuclear Glucocorticoid Receptor Binding
Identical Protein Binding
Transmembrane Transporter Binding
Protein Heterodimerization Activity
Biological Process
Microtubule Cytoskeleton Organization
Microtubule Nucleation
Mitotic Spindle Organization
Signal Transduction
Cilium Assembly
Positive Regulation Of Intracellular Protein Transport
Regulation Of Sodium Ion Transport
Glucocorticoid Catabolic Process
Intracellular Protein Transport
Signal Transduction
Intracellular Protein Localization
Substantia Nigra Development
Nuclear Receptor-mediated Glucocorticoid Signaling Pathway
Regulation Of Neuron Differentiation
Positive Regulation Of DNA-templated Transcription
Regulation Of Synaptic Plasticity
Negative Regulation Of Dendrite Morphogenesis
Membrane Depolarization During Action Potential
Presynaptic Modulation Of Chemical Synaptic Transmission
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Chaperone Mediated Autophagy
Late endosomal microautophagy
Aggrephagy
Aggrephagy
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs
Phenethyl Isothiocyanate
Diseases
Microcephalic osteodysplastic primordial dwarfism, type II (MOPD II)
Seckel syndrome
GWAS
Heel bone mineral density (
30598549
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
S100 calcium-binding protein levels (
33227023
)
Treatment resistant depression (
30468137
)
Post bronchodilator FEV1 (
26634245
)
Type 2 diabetes (
30297969
)
Interacting Genes
55 interacting genes:
AKAP6
AKAP9
ANKRD24
ARHGAP21
CALM1
CALM2
CCP110
CEP55
CEP85L
CYTH1
DISC1
DMXL2
DNM1
DNM2
DNM3
DST
EIF4G3
FEZ1
HMOX2
HUWE1
KALRN
KIF1A
KIF5C
MACF1
MADD
MAP1LC3A
MAP1LC3B
MRFAP1
MYT1L
NECAB1
NIPBL
ODF2L
PARVB
PCM1
PNISR
RPRD1A
RRBP1
RTRAF
SEPTIN7
SHTN1
SPTAN1
SPTBN1
SPTBN2
SRGAP2
ST18
SYNE1
TP53BP1
TRAF3IP1
TUBG1
TUBGCP2
TUBGCP3
UTRN
YWHAH
YWHAZ
YY1AP1
69 interacting genes:
ABL1
ARHGEF28
BAD
BCR
BRAF
CCDC125
CDC25B
CDC25C
CDC42
CDK16
CDKN1B
CHRNA4
CREBBP
EPB41L2
EPB41L3
ESR1
ESR2
EXO1
GREM1
HSPB1
ILF3
ING1
KANK1
KCNH2
KCNK15
KCNK3
KCNK9
KLC3
KRT18
MAP3K3
MAP3K5
MARK4
MDM4
MED1
MST1R
NCAM2
NCOA1
NCOA2
NCOA3
NEDD4L
NEK1
NHSL2
NR3C1
NRIP1
PARD3
PARD6A
PARD6B
PCNT
PDPK1
PRKCI
PRKN
PTH1R
RAF1
REM1
RIMS1
RIMS2
RPH3A
SAMSN1
SNCA
SRC
THRA
TLX2
TNFAIP3
TPH1
TSC1
TSC2
YWHAE
YWHAG
ZFP36
Entrez ID
5116
7533
HPRD ID
05804
00215
Ensembl ID
ENSG00000160299
ENSG00000128245
Uniprot IDs
O95613
Q04917
Q9H4N8
PDB IDs
2C63
2C74
7NMZ
Enriched GO Terms of Interacting Partners
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Cytoskeleton
Microtubule
Cell Projection
Organelle Organization
Cytoplasm
Centrosome
Microtubule Binding
Cell Projection Organization
Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane
Microtubule-based Process
Actin Binding
Centriole
Cytoskeleton Organization
Plasma Membrane Bounded Cell Projection Organization
Spectrin
Identical Protein Binding
Microtubule Nucleation
Gamma-tubulin Complex
Cell Projection Assembly
Cellular Component Assembly
Transmembrane Transporter Binding
Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Vesicle Scission
Microtubule Minus-end Binding
Ciliary Basal Body
Microtubule Organizing Center
Structural Constituent Of Cytoskeleton
Transport Along Microtubule
Microtubule Cytoskeleton
Cytosol
Plasma Membrane Bounded Cell Projection Assembly
Organelle Localization
Sarcomere
Establishment Of Organelle Localization
Cell Leading Edge
Pericentriolar Material
Cytoskeleton-dependent Intracellular Transport
Cytoplasmic Microtubule Organization
Actin Filament Binding
Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Negative Regulation Of Calcium Ion Export Across Plasma Membrane
Adenylate Cyclase Activator Activity
Calcium Channel Complex
Polar Microtubule
Actin Filament-based Process
Microtubule-based Transport
Cadherin Binding
Regulation Of Cellular Component Organization
Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Transporter Inhibitor Activity
Intracellular Signal Transduction
Nuclear Receptor-mediated Signaling Pathway
Cytosol
Regulation Of Cell Communication
Regulation Of Signaling
Regulation Of Programmed Cell Death
Regulation Of Signal Transduction
Intracellular Receptor Signaling Pathway
Regulation Of Developmental Process
Regulation Of Biological Quality
PAR Polarity Complex
Regulation Of Intracellular Signal Transduction
Regulation Of Transport
Signal Transduction
Positive Regulation Of Signal Transduction
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Protein Phosphorylation
Regulation Of Membrane Potential
Regulation Of Apoptotic Process
Regulation Of Vesicle-mediated Transport
Cell Junction Organization
Negative Regulation Of Apoptotic Process
Phosphorylation
Positive Regulation Of Metabolic Process
Enzyme Binding
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Multicellular Organismal Process
Response To Lipid
Cellular Response To Hormone Stimulus
Hormone-mediated Signaling Pathway
Positive Regulation Of Transport
Positive Regulation Of Developmental Process
Positive Regulation Of Protein Localization
Protein Kinase Binding
Regulation Of Anatomical Structure Morphogenesis
Developmental Process
Cytoskeleton Organization
Cellular Response To Lipid
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Secretion By Cell
Regulation Of Phosphorus Metabolic Process
Regulation Of Protein Localization
Positive Regulation Of Biosynthetic Process
Protein Serine/threonine Kinase Activity
Synaptic Vesicle Priming
Steroid Hormone Receptor Signaling Pathway
Nuclear Receptor-mediated Steroid Hormone Signaling Pathway
Protein Kinase Activity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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