PCNT and ODF2L

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		PCNT	ODF2L
Description		pericentrin	outer dense fiber of sperm tails 2 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Membrane Centriolar Satellite	Cytoplasm Centrosome Centriole Cytoskeleton Centriolar Satellite Ciliary Basal Body Cell Projection
	Molecular Function	Protein Binding Calmodulin Binding Molecular Adaptor Activity
	Biological Process	Microtubule Cytoskeleton Organization Microtubule Nucleation Mitotic Spindle Organization Signal Transduction Cilium Assembly Positive Regulation Of Intracellular Protein Transport	Cell Projection Organization Negative Regulation Of Cilium Assembly
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2 Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy
Drugs
Diseases		Microcephalic osteodysplastic primordial dwarfism, type II (MOPD II) Seckel syndrome
GWAS		Heel bone mineral density ( 30598549) Pre-treatment viral load in HIV-1 infection ( 31219150) S100 calcium-binding protein levels ( 33227023) Treatment resistant depression ( 30468137)	Hallux valgus ( 32131869) Intraocular pressure ( 29617998) Pulse pressure ( 30224653)
Interacting Genes		55 interacting genes: AKAP6 AKAP9 ANKRD24 ARHGAP21 CALM1 CALM2 CCP110 CEP55 CEP85L CYTH1 DISC1 DMXL2 DNM1 DNM2 DNM3 DST EIF4G3 FEZ1 HMOX2 HUWE1 KALRN KIF1A KIF5C MACF1 MADD MAP1LC3A MAP1LC3B MRFAP1 MYT1L NECAB1 NIPBL ODF2L PARVB PCM1 PNISR RPRD1A RRBP1 RTRAF SEPTIN7 SHTN1 SPTAN1 SPTBN1 SPTBN2 SRGAP2 ST18 SYNE1 TP53BP1 TRAF3IP1 TUBG1 TUBGCP2 TUBGCP3 UTRN YWHAH YWHAZ YY1AP1	9 interacting genes: APP CEP126 ERBB2 ERBB3 FBXO7 MEOX2 PCNT PIPOX PRSS23
Entrez ID		5116	57489
HPRD ID		05804	11134
Ensembl ID		ENSG00000160299	ENSG00000122417
Uniprot IDs		O95613	A0A8Q3WMC5 Q9ULJ1
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoskeleton Microtubule Cell Projection Organelle Organization Cytoplasm Centrosome Microtubule Binding Cell Projection Organization Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Microtubule-based Process Actin Binding Centriole Cytoskeleton Organization Plasma Membrane Bounded Cell Projection Organization Spectrin Identical Protein Binding Microtubule Nucleation Gamma-tubulin Complex Cell Projection Assembly Cellular Component Assembly Transmembrane Transporter Binding Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Vesicle Scission Microtubule Minus-end Binding Ciliary Basal Body Microtubule Organizing Center Structural Constituent Of Cytoskeleton Transport Along Microtubule Microtubule Cytoskeleton Cytosol Plasma Membrane Bounded Cell Projection Assembly Organelle Localization Sarcomere Establishment Of Organelle Localization Cell Leading Edge Pericentriolar Material Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Actin Filament Binding Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Calcium Channel Complex Polar Microtubule Actin Filament-based Process Microtubule-based Transport Cadherin Binding Regulation Of Cellular Component Organization Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Transporter Inhibitor Activity	ERBB3:ERBB2 Complex ErbB-3 Class Receptor Binding Glial Cell Development ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Protein Heterodimerization Activity Schwann Cell Development ERBB2 Signaling Pathway Peripheral Nervous System Development Receptor Complex Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Neuron Apoptotic Process Positive Regulation Of Establishment Of Protein Localization Regulation Of Response To Calcium Ion Positive Regulation Of Calcium-mediated Signaling Amylin Binding Positive Regulation Of Toll Signaling Pathway Growth Factor Binding Negative Regulation Of Lymphocyte Differentiation Basal Plasma Membrane Epidermal Growth Factor Receptor Signaling Pathway Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite L-pipecolate Oxidase Activity Sarcosine Oxidase Activity L-lysine Catabolic Process To Acetyl-CoA Via L-pipecolate Plasma Membrane Bounded Cell Projection Organization Wound Healing ERBB Signaling Pathway Acetylcholine Receptor Activator Activity Regulation Of Calcium-mediated Signaling Lipoprotein Particle Positive Regulation Of Protein Import Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Myelination Positive Regulation Of Cardiac Muscle Tissue Development Mitotic Spindle Organization Axon Ensheathment PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of MAPK Cascade Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Cell Projection Organization Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
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