YWHAH and KANK1

Number of citations of the paper that reports this interaction (PubMedID 18458160)
61

Data Source:
BioGRID (affinity chromatography technology, pull down)

		YWHAH	KANK1
Description		tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta	KN motif and ankyrin repeat domains 1
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Plasma Membrane Intercalated Disc Synapse Extracellular Exosome Presynapse Glutamatergic Synapse Cerebellar Granule Cell To Purkinje Cell Synapse	Nucleus Cytoplasm Cytoskeleton Plasma Membrane Cell Cortex Membrane Ruffle Membrane Cell Projection
	Molecular Function	Actin Binding Insulin-like Growth Factor Receptor Binding Protein Binding Sodium Channel Regulator Activity Enzyme Binding Protein Domain Specific Binding Nuclear Glucocorticoid Receptor Binding Identical Protein Binding Transmembrane Transporter Binding Protein Heterodimerization Activity	Protein Binding Beta-catenin Binding Protein-macromolecule Adaptor Activity
	Biological Process	Regulation Of Sodium Ion Transport Glucocorticoid Catabolic Process Intracellular Protein Transport Signal Transduction Intracellular Protein Localization Substantia Nigra Development Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Regulation Of Neuron Differentiation Positive Regulation Of DNA-templated Transcription Regulation Of Synaptic Plasticity Negative Regulation Of Dendrite Morphogenesis Membrane Depolarization During Action Potential Presynaptic Modulation Of Chemical Synaptic Transmission	Cell Population Proliferation Negative Regulation Of Neuron Projection Development Actin Cytoskeleton Organization Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Migration Negative Regulation Of Actin Filament Polymerization Regulation Of Rho Protein Signal Transduction Negative Regulation Of Rho Protein Signal Transduction Cortical Microtubule Organization Negative Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Wound Healing Podocyte Cell Migration Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Ruffle Assembly Regulation Of Establishment Of Cell Polarity Negative Regulation Of Lamellipodium Morphogenesis
Pathways		Activation of BAD and translocation to mitochondria Translocation of SLC2A4 (GLUT4) to the plasma membrane RHO GTPases activate PKNs TP53 Regulates Metabolic Genes Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex SARS-CoV-1 targets host intracellular signalling and regulatory pathways SARS-CoV-2 targets host intracellular signalling and regulatory pathways Transcriptional and post-translational regulation of MITF-M expression and activity	Estrogen-dependent gene expression Signaling by membrane-tethered fusions of PDGFRA or PDGFRB
Drugs		Phenethyl Isothiocyanate
Diseases			Cerebral palsy
GWAS		Post bronchodilator FEV1 ( 26634245) Type 2 diabetes ( 30297969)	Bone mineral density (femoral neck) in inflammatory bowel disease ( 29603369) Eye morphology ( 29921221) Fasting blood glucose ( 33842983) Fasting plasma glucose ( 25187374) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Night sleep phenotypes ( 27126917) Post bronchodilator FEV1/FVC ratio ( 26634245) Proinsulin levels (early-phase conversion) ( 23263489) Serum bilirubin levels in metabolic syndrome ( 30621171) Systolic blood pressure ( 30224653) Uterine fibroids ( 30194396)
Interacting Genes		69 interacting genes: ABL1 ARHGEF28 BAD BCR BRAF CCDC125 CDC25B CDC25C CDC42 CDK16 CDKN1B CHRNA4 CREBBP EPB41L2 EPB41L3 ESR1 ESR2 EXO1 GREM1 HSPB1 ILF3 ING1 KANK1 KCNH2 KCNK15 KCNK3 KCNK9 KLC3 KRT18 MAP3K3 MAP3K5 MARK4 MDM4 MED1 MST1R NCAM2 NCOA1 NCOA2 NCOA3 NEDD4L NEK1 NHSL2 NR3C1 NRIP1 PARD3 PARD6A PARD6B PCNT PDPK1 PRKCI PRKN PTH1R RAF1 REM1 RIMS1 RIMS2 RPH3A SAMSN1 SNCA SRC THRA TLX2 TNFAIP3 TPH1 TSC1 TSC2 YWHAE YWHAG ZFP36	9 interacting genes: AKT1 BAIAP2 PPP1CA YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Entrez ID		7533	23189
HPRD ID		00215	09651
Ensembl ID		ENSG00000128245	ENSG00000107104
Uniprot IDs		Q04917 Q9H4N8	A0A8I5KRP2 A0A8I5KT40 A0A8I5KZ49 Q14678
PDB IDs		2C63 2C74 7NMZ	5YBJ 5YBU 8AS9 8IVZ 8IW0
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction Nuclear Receptor-mediated Signaling Pathway Cytosol Regulation Of Cell Communication Regulation Of Signaling Regulation Of Programmed Cell Death Regulation Of Signal Transduction Intracellular Receptor Signaling Pathway Regulation Of Developmental Process Regulation Of Biological Quality PAR Polarity Complex Regulation Of Intracellular Signal Transduction Regulation Of Transport Signal Transduction Positive Regulation Of Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Protein Phosphorylation Regulation Of Membrane Potential Regulation Of Apoptotic Process Regulation Of Vesicle-mediated Transport Cell Junction Organization Negative Regulation Of Apoptotic Process Phosphorylation Positive Regulation Of Metabolic Process Enzyme Binding Negative Regulation Of Programmed Cell Death Positive Regulation Of Macromolecule Metabolic Process Regulation Of Multicellular Organismal Process Response To Lipid Cellular Response To Hormone Stimulus Hormone-mediated Signaling Pathway Positive Regulation Of Transport Positive Regulation Of Developmental Process Positive Regulation Of Protein Localization Protein Kinase Binding Regulation Of Anatomical Structure Morphogenesis Developmental Process Cytoskeleton Organization Cellular Response To Lipid Positive Regulation Of Intracellular Signal Transduction Regulation Of Secretion By Cell Regulation Of Phosphorus Metabolic Process Regulation Of Protein Localization Positive Regulation Of Biosynthetic Process Protein Serine/threonine Kinase Activity Synaptic Vesicle Priming Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Protein Kinase Activity	Protein Domain Specific Binding Phosphoserine Residue Binding Protein Sequestering Activity Protein Targeting Intracellular Protein Localization Identical Protein Binding Extracellular Exosome Establishment Of Protein Localization Transmembrane Transporter Binding Focal Adhesion Substantia Nigra Development Glutamatergic Synapse TORC1 Signaling Presynapse Neural Nucleus Development Negative Regulation Of TORC1 Signaling Positive Regulation Of Toll-like Receptor Signaling Pathway TOR Signaling Negative Regulation Of TOR Signaling Regulation Of TORC1 Signaling Melanosome Regulation Of Translational Initiation Regulation Of Cell Communication Regulation Of Signaling Negative Regulation Of Transmembrane Transport Cytosol Insulin-like Growth Factor Receptor Binding Enzyme Binding Protein Localization To Endoplasmic Reticulum Positive Regulation Of Glycogen Biosynthetic Process Cadherin Binding Involved In Cell-cell Adhesion Regulation Of Monoatomic Ion Transport Regulation Of Protein Localization Negative Regulation Of Transport Regulation Of Membrane Potential Regulation Of Biological Quality Regulation Of TOR Signaling Negative Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Protein Localization To Nucleus Protein K6-linked Ubiquitination Intracellular Signal Transduction Vesicle Negative Regulation Of Immune System Process Regulation Of Glycogen Biosynthetic Process Cellular Response To Starvation Signal Transduction 14-3-3 Protein Binding Regulation Of Synaptic Plasticity Regulation Of Signal Transduction Negative Regulation Of Protein Localization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?