PCNT

Gene Name		pericentrin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Pericentriolar Material Cytoplasm Centrosome Centriole Cytosol Microtubule Membrane Motile Cilium Centriolar Satellite Ciliary Basal Body Intercellular Bridge
	Molecular Function	Protein Binding Calmodulin Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Mitotic Cell Cycle In Utero Embryonic Development Neuron Migration Organelle Organization Spindle Organization Cerebellar Cortex Morphogenesis Olfactory Bulb Development Limb Morphogenesis Multicellular Organism Growth Cilium Assembly Negative Regulation Of Apoptotic Process Brain Morphogenesis Neural Precursor Cell Proliferation Positive Regulation Of Intracellular Protein Transport
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-protein Interactions		11 interactors: AKAP9 CALM1 CALM2 CCP110 CEP55 DISC1 PCM1 TP53BP1 TUBG1 TUBGCP2 TUBGCP3
Entrez ID		5116
HPRD ID		05804
Ensembl ID		ENSG00000160299
Uniprot IDs		O95613
PDB IDs
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Mitotic Cell Cycle Microtubule Cytoskeleton Organization Microtubule Nucleation Cell Cycle Process Microtubule Polymerization Microtubule-based Process Cell Cycle Organelle Organization Microtubule Polymerization Or Depolymerization Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Transporter Activity Regulation Of Cytokinesis Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cytoskeleton Organization Regulation Of Heart Rate Positive Regulation Of Ion Transmembrane Transport Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Protein Polymerization Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Heart Contraction Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process
Tagcloud ?		aberration arg585x assumed bones capabilities careful derive discreet disturbance dwarfism firm glu1774x heterozygous integrating intrauterine leu1361arg microcephaly mopd moyamoya proportionate provoke retardation segregate sga somatotropic specification suggestive syndromic underline